Bydureon and Nausea: What Users Say (Page 3)

• Fan...
• Taken for less than 1 month
• June 19, 2012

For Type 2 Diabetes "Just took my 2nd injection (the first without supervision) this morning. As others have said, the needle is larger than I'm used to, and the mixing is a little cumbersome, but I'm willing to stick with it. I had to stop both Byetta and Victoza due to horrendous side effects. I'm praying that Bydureon won't make me as nauseous."

• Fre...
• May 3, 2016

For Type 2 Diabetes "I took my second injection this morning. I have thus far no issue with injection. I do not have a lump like most people seem to have. Injection goes well and easy for me. My first side effects after the first injection came on day 2. I had terrible nausea for about 1 hour, then it went away. I had diarrhea off and on all week and occasional nausea that didn't last long. I'm hoping I'll adjust to the med and those side effects go away. I did notice a slight decrease in my appetite. I also noticed if I ate too much, I would get sick. No weight loss to report yet, but in the first week of injection, I noticed a big improvement in my blood sugars. Fasting blood sugar was normally 215, it is now in the 180s. I'm hoping for more improvement over time."

• pen...
• February 26, 2014

"I have taken Bydureon for four weeks. My initial injection was done at the doctor's office with a nurse standing by. I had a few moments of nausea, but they were rare and far between. My nausea would only get worse the day before I took the next dose. When I took my third dose, however, I got the worst burning rash that grew to the size of a dollar bill. It still hasn't completely gone away. My doctor suggested changing the site of the injection. Within an hour of the fourth injection (on my thigh), a burning rash appeared. The doctor is switching me to Victoza. Other than the rash, I lost 10 pounds in the first two weeks because of loss of appetite."

• taz...
• April 17, 2016

For Type 2 Diabetes "I started this 4 weeks ago, I am ready to quit, my nausea is so bad, it is hard to deal with. I was told it would go away, not! My sugars are running a lot lower, and I stopped the actos. I feel like it is a huge rock in my stomach, and looking, smelling, or trying to eat makes me want to gag. I am hanging on one more week. My daughter is a nurse and does my injections, you need to do stomach and pinch up the skin, making sure you don't see any veins. I have lost 10#. When I lay down to sleep, I get heartburn really bad. I can't even sleep, I toss and turn, sometimes the whole 8 hours, I am miserable!!!"

• Kar...
• Taken for 2 to 5 years
• December 30, 2019

For Type 2 Diabetes "Drug seems to work well. My A1C is under 7. I've been on it for several years in conjunction with Invokana. I have not had the nausea, vomiting, or other side effects that many have reported. My complaint is the delivery pen/needle itself. It's horrible. There is no way the patient can be getting the full dose. After you mix the powder and solution, several drops escape out of the needle. The directions say to leave the needle inserted in the skin for 10 seconds after injecting. When you pull the needle out, the medication leaks. And there are always droplets still coming out of the needle despite how much pressure I put on the plunger while injecting. Just a horribly designed delivery mechanism. But, on the bright side, the manufacturer covers my insurance co-pay, so this medication costs me nothing out of pocket."

• red...
• May 31, 2013

For Type 2 Diabetes "I've been taking Bydureon for 2 months and have knots at each injection site. The last one is red and itchy. Won't see the doctor for another three weeks, so hopefully the A1C is much better. I've lost 10 pounds, have slight nausea, and occasional low blood sugar. Because of my lifelong aversion to needles, my husband gives me my shot, bless him. I just cannot make myself do the injection. I experience a good bit of stinging when the medication is going in. I'd been taking Januvia for a couple of years and have developed nodules (benign, so far) on my thyroid. I'm concerned that my doctor prescribed Bydureon, given my recent thyroid history."

• Chr...
• Taken for less than 1 month
• November 17, 2019

For Type 2 Diabetes "My doctor discontinued my Bydureon. I was taking it for six weeks with only slight nausea and small bumps at the injection site. But when I took my sixth injection, I wound up in the hospital with vomiting and diarrhea. I couldn't keep anything down, and I spent the weekend in the hospital as they flushed my system. Some people tolerate it, some don't. Obviously, I was in the later category."

• Fre...
• Taken for 1 to 6 months
• June 12, 2016

For Type 2 Diabetes "UPDATE: So I've been on Bydureon for 6 weeks. I do now get the itchy lumps at the injection site. The nausea I had in the beginning is gone. Blood sugars are much better. No weight loss to report and what little appetite suppression I had in the beginning is also gone. I am 40 lbs overweight and just absolutely struggle to lose 1 pound. I was really hoping this would work for me in losing weight. So far, nothing."

• TLS...
• Taken for 1 to 6 months
• August 29, 2013

For Type 2 Diabetes "I've been on this medication since 3/28/13. In June, my A1C was down to 6.4. My next appointment is the end of September. 6-8 weeks into using Bydureon, I started experiencing nausea approximately 24-48 hours after injection, which lasted for 24-72 hours. In June, my doctor suggested I stop the Bydureon because he didn't like that I was feeling sick for half of my week. I had 1 month of medication left, so I agreed to stick with it one more month. Nausea went away, but I still had no appetite. Now I'm experiencing stomach pain with movement 24 hours after injection. I see the doctor at the end of September."

• Akm...
• Taken for less than 1 month
• April 15, 2015

For Type 2 Diabetes "I've been on Bydureon coming on three weeks, I just gave my third week shot today! The first week, about five days in, I got violently ill: abdominal cramps, vomiting, diarrhea. Contacted my doctor, but he really thought that it was the stomach virus, so he asked me to take it for one more week. Second week, I had some light nausea, but all went well. Just took my third shot this morning, and I don't know if I did anything wrong, but it burned going in, and now there's a lump on my thigh the size of a pea."

• cat...
• Taken for 1 to 6 months
• December 14, 2019

For Type 2 Diabetes "My second time on Bydureon Bcise. After 3 boxes, 12 weeks, although I had tolerable stomach problems before, these turned into full-blown nausea and diarrhea that has now lasted 4 days. It keeps blood sugar under control with no added medications, but I can't get more than 5 feet from the toilet. It's debilitating at this point. If I take Imodium AD, it does stop diarrhea, but promotes the nausea. Trying to keep from getting dehydrated as all I pass is water in the diarrhea. Trying to get this out of my system. I will not take another injection. Do not know what I will do. This med hits you unexpectedly. Don't know when it will make you sick. This is my second try with this med. Trulicity doesn't work nor anything else for that matter. This med works for blood sugar, but I'm horribly sick."

• Fee...
• Taken for less than 1 month
• August 14, 2017

For Type 2 Diabetes "I have been on Bydureon for just under a week. I have not been able to eat very much. I am nauseous every day and have very little energy. I've been considering going to see my doctor to see what's wrong with me, but I see from these messages that it's probably from the injection. Of course, I've lost a few pounds because I cannot eat anything. I HATE HOW I FEEL!"

• Dal...
• Taken for 1 to 2 years
• August 24, 2019

For Type 2 Diabetes "When I started taking Bydureon, it was great. I lost 4 kg over 3 months, it made a huge difference. After about 6 months, I started having stomach issues. I was nauseated most days, and I spoke to my diabetic educator about going back on insulin, but they suggested I stay on the Bydureon for another 6 months. Those 6 months were the absolute worst. I now have constant stomach issues, gastroparesis is my main issue. I never had this before I started Bydureon, but my GP or DE are unwilling to take me off it, so I have stopped myself. After 1 month, I feel so much better, nausea is way less. My experience with Bydureon has been overwhelmingly negative."

• Mat...
• Taken for 1 to 6 months
• March 28, 2019

For Type 2 Diabetes "I have been on Bydureon on 2 different occasions over the last year. The first time I took it for about 3 months. I quit because I was getting very lightheaded and nauseous, as well as my sugar would drop very low after an injection. After about 6 months, I thought I'd try again. I changed my injection time to after a meal and would skip my metformin at that meal. It seemed to take care of the sugar crash, but still feel awful most of the time. Nausea, loss of appetite, and lethargic. I think I'll just stop again. P.S. It did work. My A1C dropped from high 7's to low 6's. Just miserable with the side effects."

• Cam...
• April 25, 2018

For Type 2 Diabetes "My husband has been on Bydureon for 8 weeks. He was due for his 9th injection on Sunday last week but fell really ill about 24 hours after his 8th injection. It's now been 8 days since he fell ill with nausea, burping, heartburn, and constipation, with the occasional vomiting. How long until he will start to feel some normality? He has now had 6 days off work, and all he does is sleep. HELP."

• Nan...
• Taken for 1 to 6 months
• March 27, 2018

For Type 2 Diabetes "Added Bydureon to my usual metformin dose in June 2017. Had six months of persistent nausea, vomiting, diarrhea, and increasing sensation of liver fullness/discomfort. (It looks like I'm one of the group described by the package insert, who develop significant adverse effects.) At the injection sites, developed firm nodules that each took 2-3 months to resolve and became itchier the longer I was on the medication. I lost about 10 lb and had great readouts on A1c, but couldn't bear to take Bydureon beyond December 2017. In my view, not a success therapeutically."

• SBi...
• October 28, 2015

For Type 2 Diabetes "All was fine the first week, a little nausea. Second week was fine as well, but a little redness/itching around the injection site. Third week, the injection site immediately started to turn into a giant hive across my entire abdomen, and I broke out in hives in all other areas of my body. Went to the ER and was taken off medication, but it took over a week for the serious reaction to stop. Developed 1-inch knots at all injection sites, which lasted for a couple of months. I've been off the meds for several months and still break out in hives around my waist and on my bra line. Prior to the first hive outbreak, I had never had allergic reactions to anything."

• Geo...
• Taken for less than 1 month
• April 27, 2016

For Type 2 Diabetes "I am on my third injection of Bydureon. The needle is huge, and the med burns going in and bleeds after. No problems with the injection site till this week, I noticed a small pea-sized bump at the first injection site on my stomach. The first two weeks, my morning sugars went up significantly to 190-200. Other side effects are diarrhea (which has resolved this week), bloating, a very uncomfortable full feeling, and some random stomach pain. This week numbers are starting to come down to 145-155, but still higher than when on my previous med, Victoza, which made me very nauseous. Not losing weight. In fact, I am up 2 lbs. Hope this turns around in the next couple of weeks."

• Hot...
• Taken for 1 to 6 months
• September 15, 2017

For Type 2 Diabetes "I've been taking Bydureon for 4 weeks now and have lost 5 kg. The only side effects I have had are heartburn, nausea, and headaches, but they have stopped. I do recommend this drug to anyone. It does suppress the appetite really well. I take it with Metformin. I get it through prescription, which costs $5.60 a month."

• aa1...
• July 19, 2017

For Type 2 Diabetes "A few years ago, I started with Trulicity, then insurance made me switch to Tanzeum, and now I had to switch to Bydureon. A couple of issues: the corkscrew on my second box. When I twist the green, I hear the click, and the medicine window only has part of the liquid, the base has pushed out some of the medicine into the cap. I take off the needle cap, and there is liquid in the cap at $125 a pen. So, either I have a bad box of four, or there is a defect on these. It did not happen on box one, but on box two, the first two pens had this. The first and second-day side effects for me are horrendous: nausea and just feel awful. I never had these issues with prep or side effects with either Trulicity or Tanzeum. But it's all up to insurance companies in the end, they decide what is best for you."

• T27...
• August 26, 2017

For Type 2 Diabetes "I have been on it for 8-9 weeks. The only side effect I have had outside the last two days is loss of appetite, which is wonderful for a binge eater like myself. You not only get full sooner, you almost feel sick. I don't mind, it reminds me I need to keep myself in check. Until the last two days, I have not had the nausea and vomiting others seem to have. I don't know why it decided to start. I vomited two days in a row now. Hope it doesn't continue, I otherwise love it."

• Min...
• Taken for 2 to 5 years
• July 28, 2018

For Type 2 Diabetes "My husband has been taking Bydureon for two and a half years. His sugars are down, but he experienced nausea, headaches, and loss of appetite at the beginning. He has lost some weight also without doing any extra exercise. He still has a general feeling of not knowing what he wants to eat - he complains that food has no taste. He used to eat cereal for breakfast, but now sometimes only eats 1 meal a day and makes up for it with noodles, etc. Will his diet ever get back to normal?"

• Mrm...
• Taken for 6 months to 1 year
• March 3, 2021

For Type 2 Diabetes "On weekly Ozempic, I had extreme side effects such as nausea, headache, body ache, fatigue, and extreme brain fog, but it did work much better than metformin at lowering my blood sugar. Bydureon once a week worked just as well at lowering my sugar levels, and the side effects were less, although pretty much similar, just not quite as bad. My only other complaint is that the Bydureon delivery injector is a monstrous device that seems like it was designed by Rube Goldberg, and there is always one out of four doses that seemingly has no effect, like they slip a placebo dose in every month's supply for some reason! (P.S., I recommend B vitamins while taking diabetic drugs, they tend to keep you from absorbing certain essential nutrients for some reason, especially B vitamins.)"

• Min...
• Taken for 1 to 6 months
• August 9, 2018

For Type 2 Diabetes "To Brownie... I have taken Bydureon for 3 months and had some symptoms like yours. I also had a dull ache in my upper right abdomen under my ribs. Mine also is not gallbladder, liver, or pancreas. I felt sick, nauseated, had periodic vomiting, no energy, nodules at injection sites, itching, cellulitis, burping, bloating, and in general have to force myself to do things. I stopped taking Bydureon 2 weeks ago and am starting to feel better. I still have the nausea and bloating. When I started, I was told side effects decrease after 2 weeks, but I felt worse the longer I took it. It did decrease my readings, from the 300s to the 150s...still not that great but better. I read it can take up to 10 weeks to be completely out of your system."

• Daw...
• Taken for less than 1 month
• March 18, 2015

For Type 2 Diabetes "I have an A1C of 6.2. I am 265 pounds. I just started Bydureon yesterday, my Dr. office gave me the first one free, and I gave myself the first injection. I have had some mild nausea. I have not had the desire to eat very much and, in fact, went to bed without eating any dinner, had an overall odd full feeling. I am nervous because I have seen so many reviews of people that had a lot of nausea and vomiting. So far, so good, but it still worries me. I really want to lose weight and feel better."