Eptinezumab and Allergic Reaction: What Users Say

• dov...
• Taken for 1 to 2 years
• November 6, 2021

For Migraine Prevention "I have chronic migraines, some of which are hemiplegic, and I have tried so many drugs that didn't work - oral preventatives, Botox, Emgality, etc. Vyepti is the only drug that has helped me at all. Due to my migraine severity, I get the 300 mg dose once every three months. Vyepti brings my head pain from an 8 down to 5, 6, or 7, depending on my menstrual cycle timing. I have far less hemiplegic migraine aura, so I only have full-blown body weakness and trigeminal neuralgia-like face pain at the end of my three-month Vyepti cycle. Pros: less head pain, less face pain, less severe aura, lasts months, manageable short-lived side effects, less painful than self-injected CGRPs, doesn't upset the stomach. Cons: due to my migraine frequency, it takes 1-2 weeks to kick in after infusion, 2 weeks of allergy symptoms after infusion (runny nose, sneezing, itchy eyes, nose, throat, fatigue), nausea after 300 mg infusion (easily fixed with IV Zofran, does not occur with 100 mg dose)."

• Anonymous
• Taken for less than 1 month
• November 23, 2022

For Migraine Prevention "I just got my first dose of Vyepti 100 mg 3 weeks ago. It has helped me with my migraines, but it has caused me to have major pain in my joints to the point of keeping me up, crying all night. Trouble walking around far. I have been on every medication for migraines on the market. Nothing has helped until I tried this medication. The way I feel, I think I would rather have a migraine than deal with this pain. I have seizures, and I am allergic to almost every medication on the market. Plus, some medication can’t be taken with my seizure medication. This was my first, and I think my last!"

• Itc...
• Taken for less than 1 month
• June 16, 2022

For Migraine Prevention "Not so great, I had an allergic reaction and an ongoing migraine for days accompanying the allergic reaction. I am allergic to a lot of things, though. 100 mg dose."