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Efinaconazole topical and Itching: What Users Say

Brand names: Jublia

Itching: mentioned by 10 users (4.4%)

Based on user experiences from 229 Efinaconazole topical reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

blisters 5.7%
itching 4.4%
swelling 3.5%
pain 2.2%
redness 1.7%
burning 1.3%

Reviews for Efinaconazole topical

Commonly mentioned side effects
  • Nor...
  • Taken for 1 to 6 months
  • May 14, 2019

For Onychomycosis, Toenail "My doctor gave me the prescription for Jublia December 6, 2018, and I’ve used it faithfully every day since. The only toes affected were my big toes, and one of those had a minor infection. I literally removed the whole toenail on the bad toe and started using the product. It’s now mid-May 2019, and my toenails are both nice pink. I just purchased the second 8 ml bottle, and I believe it will last the full 48 weeks of treatment. $140 each, so hopefully that’s it. $280 is a small price to pay to clear up the awful itching. I think people may use the product improperly or quit too soon. I sure have found Jublia to be effective."

9 / 10
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  • DrJ...
  • Taken for 1 to 6 months
  • March 14, 2018

For Onychomycosis, Toenail "My left big toenail has a fungal infection that affects about 25% of the toenail and has been present for about 4 years. I took 3 months of oral Lamisil, and the new nail has been growing back perfectly clear. It has grown out about 50%. I started using Jublia after I stopped the oral Lamisil on the affected part of the nail that hadn't grown out yet. I didn't have any problems until after about 3 months of daily use. About a month ago, I started developing small, painful, itching, burning blisters around the skin of the big toenail. I stopped using Jublia, and it took about 3 weeks to clear up. I wasn't sure what caused this but decided to try Jublia again on the toenail because I'm paranoid the remaining fungus will spread to my new unaffected nail. Within 48 hours, the small itching blisters returned, so I'm sure it is the most likely cause since I haven't applied anything else to the toenail."

3 / 10
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12 Report
  • Jaj...
  • Taken for 6 months to 1 year
  • September 6, 2017

For Onychomycosis, Toenail "The medicine was effective, and I was beginning to see improvement in my nail after a few months, then started having painful redness, blisters, itching, and swelling. It is miserable. I've stopped using it until all these side effects go away. I'm very disappointed in having to stop using Jublia, as it was really beginning to get rid of the fungus. Before I knew what was causing these problems, I asked my dermatologist if it could be the medicine, and he said he'd never had a patient to have these side effects using it. I found out on my own that it was the Jublia."

7 / 10
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13 Report

Frequently asked questions

  • Cou...
  • February 8, 2021

For Onychomycosis, Toenail "Prescribed by doctor for nail fungus on fingernails. Nails lifted and got worse, cuticles swelled and oozed yellow, fingertips blistered, painful. Used for 1 month. Went through multiple prescriptions for skin infections. Went to a London Drugs pharmacy to talk to a pharmacist. He took one look and suggested a dermatologist for possible reactions and recommended stopping everything and just keeping nails dry and letting them heal. Went to the doctor, and he agreed. Stop using Jublia. 2 months later, when my hands were better but still dealing with nail fungus - and waiting for nail culture. Tried it once as per directions and went through 5 days of swelling, itching, burning, and blisters. Horrible product. Took Lamisil pills for a month, and nail fungus is stopped and my nails are healthy. Just a heads up for anyone else, using the product and possibly being told to be patient, keep using it - it’s simply the debridement from the nail growing out."

1 / 10
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8 Report
  • Lul...
  • Taken for 1 to 2 years
  • December 22, 2023

For Onychomycosis, Toenail "Slow working but effective in terms of about 18 months. I then took a few months' break, and upon restarting, I developed a severe chemical burn on the skin around both the toenails. The entire toes and adjacent toe were involved. I had redness, blisters, bleeding, and intense itching. One of the toenails detached completely. At first, I didn't think it was Jublia, but it's confirmed. The healing process was very slow, a few months for the skin to be back to almost normal. I'm still struggling."

3 / 10
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3 Report

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  • FMS...
  • Taken for 1 to 6 months
  • March 30, 2018

For Onychomycosis, Toenail "I have had fungal toenails on 4 toes for decades. I used one bottle of Jublia and could see improvements. Unfortunately, partway through the second bottle, I developed an allergic reaction - severe itching and blistering. It is too severe to continue. One application causes the severe blisters, redness, itching, and weeping. It is disappointing but not uncommon for me to develop skin allergies. I have also developed reactions to tea tree oil, Vick's Vapor Rub, benzoyl peroxide."

5 / 10
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10 Report
  • lol...
  • June 29, 2016

For Onychomycosis, Toenail "I have been using Jublia for 3 months now. I apply it every evening, keep the nail clipped, filed, clean, and dry. No improvement. Woke up this morning to find red, itchy, and blistered skin and clear pinkish fluid oozing from under my nail! It looks very painful, but I don't feel a thing, thank goodness! While I'm waiting to hear back from my Dr., I'll fill you in on the cost. First, I went to CVS to find out it was $628.00! Received a Walgreens coupon from my Dr., which my insurance allowed for $125.00."

1 / 10
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12 Report
  • Lar...
  • Taken for less than 1 month
  • March 24, 2018

For Onychomycosis, Toenail "I bought it without a prescription. It dissolved my thumbnail, which came off completely. The area above the nail blistered, itched, and was heat sensitive. The nail grew back but came off again. Now a deformed, lumpy nail-like thing is growing back. I recently briefly treated the itchy area with tea tree oil and Dimethyl sulfoxide (DMSO), and the itching stopped and the blister went away. It feels normal now but looks terrible."

1 / 10
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8 Report
  • Dee...
  • February 5, 2018

For Onychomycosis, Toenail "I had a fingernail infection called onycholysis, which is the separation of the fingernail and the nail bed, and chemical burns due to a nail salon using unsterile equipment. I went to my dermatologist, and she took a biopsy of my nails the same day she prescribed Jublia. She didn't even know I had a fungal infection! This medicine is for toenail fungal infections like onychomycosis ONLY!!! Not only did I have adverse reactions to this medicine, but I had to pay $3,200 for 3 bottles. I had burning, itching, swelling, blisters, and pain from using Jublia. It is NOT MEANT FOR FINGERS, and I contacted the manufacturer, who said it is NOT FDA APPROVED FOR FINGERS either. She is erroneously prescribing this topical solution to her patients and making their fingernail infections worse! I am going to file a complaint. I want my money back and compensation for my pain and suffering for this mistake that my doctor made!"

2 / 10
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8 Report
  • 1Be...
  • September 12, 2017

For Onychomycosis, Toenail "I have been fighting nail fungus for over 30 years; I've tried griseofulvin, Lamisil, and then Jublia in 2015. I did Jublia for 10 months and then got a severe skin reaction: intense itching, blisters, etc. The podiatrist had me soaking my feet, trying this cream, etc. I went off Jublia and let my skin get back to normal, which took a few months. I just restarted back on it after over a year off because it's the only thing that has worked. The itching returned immediately; I am trying to manage it."

8 / 10
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6 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.