Efinaconazole topical and Blisters: What Users Say

• Mar...
• Taken for 1 to 6 months
• July 28, 2016

For Onychomycosis, Toenail "My podiatrist prescribed JUBLIA for a minor fungus in 2 toenails in March 2016. When I found out the outrageous price, I asked for other options, and she mentioned laser, but my insurance would not cover the $100 per nail, and according to her, I would have to treat the 10 toenails for it to work. My copayment was $60 a month, and I did 5 months. My nails were getting worse with blisters, bleeding, and finally, it was making holes in the skin of my toes. I went today, and she informed me that I had a reaction to the medicine and to stop applying it and prescribed a steroid cream. A topical prescription that cost $630 should have alerted me that whoever is prescribing it is getting a big kickback. Social media will be alert."

• jim...
• Taken for 1 to 6 months
• February 18, 2022

For Onychomycosis, Toenail "I applied Jublia nightly to my right bud toe. At about day 32, it began to get sore. After two more days, the toe was becoming reddened, inflamed, a bit swollen, and small blisters appeared on the skin near the nail. Most of that nail or the area beneath the nail appears white. I discontinued the med at that point. At 39 days, the inflammation persists. There is some weeping serous fluid coming from under the nail. Still quite swollen. Don't think it's infected, but I'll keep an eye on it, of course. Would NOT recommend."

• Jaj...
• Taken for 6 months to 1 year
• September 6, 2017

For Onychomycosis, Toenail "The medicine was effective, and I was beginning to see improvement in my nail after a few months, then started having painful redness, blisters, itching, and swelling. It is miserable. I've stopped using it until all these side effects go away. I'm very disappointed in having to stop using Jublia, as it was really beginning to get rid of the fungus. Before I knew what was causing these problems, I asked my dermatologist if it could be the medicine, and he said he'd never had a patient to have these side effects using it. I found out on my own that it was the Jublia."

• Cou...
• February 8, 2021

For Onychomycosis, Toenail "Prescribed by doctor for nail fungus on fingernails. Nails lifted and got worse, cuticles swelled and oozed yellow, fingertips blistered, painful. Used for 1 month. Went through multiple prescriptions for skin infections. Went to a London Drugs pharmacy to talk to a pharmacist. He took one look and suggested a dermatologist for possible reactions and recommended stopping everything and just keeping nails dry and letting them heal. Went to the doctor, and he agreed. Stop using Jublia. 2 months later, when my hands were better but still dealing with nail fungus - and waiting for nail culture. Tried it once as per directions and went through 5 days of swelling, itching, burning, and blisters. Horrible product. Took Lamisil pills for a month, and nail fungus is stopped and my nails are healthy. Just a heads up for anyone else, using the product and possibly being told to be patient, keep using it - it’s simply the debridement from the nail growing out."

• FMS...
• Taken for 1 to 6 months
• March 30, 2018

For Onychomycosis, Toenail "I have had fungal toenails on 4 toes for decades. I used one bottle of Jublia and could see improvements. Unfortunately, partway through the second bottle, I developed an allergic reaction - severe itching and blistering. It is too severe to continue. One application causes the severe blisters, redness, itching, and weeping. It is disappointing but not uncommon for me to develop skin allergies. I have also developed reactions to tea tree oil, Vick's Vapor Rub, benzoyl peroxide."

• FMS...
• Taken for 1 to 6 months
• March 30, 2018

For Onychomycosis, Toenail "I have had fungal toenails on 4 toes for decades. I used one bottle of Jublia and could see improvements. Unfortunately, partway through the second bottle, I developed an allergic reaction - severe itching and blistering. It is too severe to continue. One application causes the severe blisters, redness, itching, and weeping. It is disappointing but not uncommon for me to develop skin allergies. I have also developed reactions to tea tree oil, Vick's Vapor Rub, benzoyl peroxide."

• Lul...
• Taken for 1 to 2 years
• December 22, 2023

For Onychomycosis, Toenail "Slow working but effective in terms of about 18 months. I then took a few months' break, and upon restarting, I developed a severe chemical burn on the skin around both the toenails. The entire toes and adjacent toe were involved. I had redness, blisters, bleeding, and intense itching. One of the toenails detached completely. At first, I didn't think it was Jublia, but it's confirmed. The healing process was very slow, a few months for the skin to be back to almost normal. I'm still struggling."

• Dev...
• Taken for less than 1 month
• April 30, 2017

For Onychomycosis, Toenail "Beware! Make sure your podiatrist tests your nails for fungus! I saw three podiatrists that did not test and wanted me to take Lamisil. I refused to possibly trade my liver for pretty nails. So, when podiatrist #2 suggested removing the nail and using topical Jublia when it started growing back in, I jumped on it, thinking topical is safer. Within two weeks of using Jublia, all my toes became affected and red and blistered. I thought I had athlete's foot, so I continued while using foot powders and sprays too! Two dermatologists later, I never had fungus; it was psoriasis! Jublia was a 'traumatic' event to my toenails and made the underlying psoriasis go nuts. Now, over a year and a half later, I have psoriatic arthritis in my feet and hands."

• Lar...
• Taken for less than 1 month
• March 24, 2018

For Onychomycosis, Toenail "I bought it without a prescription. It dissolved my thumbnail, which came off completely. The area above the nail blistered, itched, and was heat sensitive. The nail grew back but came off again. Now a deformed, lumpy nail-like thing is growing back. I recently briefly treated the itchy area with tea tree oil and Dimethyl sulfoxide (DMSO), and the itching stopped and the blister went away. It feels normal now but looks terrible."

• Dee...
• February 5, 2018

For Onychomycosis, Toenail "I had a fingernail infection called onycholysis, which is the separation of the fingernail and the nail bed, and chemical burns due to a nail salon using unsterile equipment. I went to my dermatologist, and she took a biopsy of my nails the same day she prescribed Jublia. She didn't even know I had a fungal infection! This medicine is for toenail fungal infections like onychomycosis ONLY!!! Not only did I have adverse reactions to this medicine, but I had to pay $3,200 for 3 bottles. I had burning, itching, swelling, blisters, and pain from using Jublia. It is NOT MEANT FOR FINGERS, and I contacted the manufacturer, who said it is NOT FDA APPROVED FOR FINGERS either. She is erroneously prescribing this topical solution to her patients and making their fingernail infections worse! I am going to file a complaint. I want my money back and compensation for my pain and suffering for this mistake that my doctor made!"

• Inf...
• May 28, 2023

For Onychomycosis, Toenail "I’ve had a very mild toenail fungal infection for decades. Can’t really remember not having it. It neither progressed beyond a quarter-inch strip at the end of both big toenails, but given the attention it’s received in media, especially the risk of spreading to others, I decided to “cure” it. There was no spreading to my other toes, though. Saw my family doctor and was prescribed Jublia, and soon after the refill of my first bottle, I developed a SEVERE reaction - blistering, swelling, rash, and redness. I didn’t link the problem to Jublia but did discontinue use. It took months for the skin on my toes to heal and constant attention to avoid infection. No change to my fungal infection, so a few days ago, I decided to apply the tiniest bit just to the very tip of the nail, and BOOM, a severe reaction within 2 - 3 hours."

• 1Be...
• September 12, 2017

For Onychomycosis, Toenail "I have been fighting nail fungus for over 30 years; I've tried griseofulvin, Lamisil, and then Jublia in 2015. I did Jublia for 10 months and then got a severe skin reaction: intense itching, blisters, etc. The podiatrist had me soaking my feet, trying this cream, etc. I went off Jublia and let my skin get back to normal, which took a few months. I just restarted back on it after over a year off because it's the only thing that has worked. The itching returned immediately; I am trying to manage it."

• Dar...
• Taken for 6 months to 1 year
• August 27, 2020

For Onychomycosis, Toenail "Have used Jublia twice and both times lost almost all the skin on both feet, even absorbed into my hands, which also shed the palms! Had blisters, redness, weeping nails, and dryness, worse than the initial problem and look at the cost. This is awful!!!"