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Doxycycline and Upset Stomach: What Users Say (Page 4)

Brand names: Vibramycin, Monodox, Adoxa, Doryx, Oracea, Doxy 100, Avidoxy, Acticlate, Doryx MPC, Doxy-Caps, Targadox, Morgidox, LymePak, Mondoxyne NL, Doxy-D, Oraxyl, Alodox, Adoxa Pak, Adoxa TT, Adoxa CK, Uracil Okebo Doxy 200 …show all brand names

Reviews for Doxycycline

Commonly mentioned side effects
  • Ray...
  • May 29, 2015

For Acne "Only got a 5 because it worked amazingly with my cystic acne, but after almost 3 months, the side effects have become unbearable. My chest and throat hurt like hell, swallowing water feels like I tried to eat a Brillo pad. I've been avoiding eating because it hurts so much. Doctor took me off it, but says my body has to heal on its own. If you start having stomach problems, beware. I told my doctor and she said to take it with food and I'll be fine. BULL! This throat and chest pain is almost as bad as when I got my tonsils out. My primary care recommended birth control as an alternative. We'll see how that works."

5 / 10
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  • cyn...
  • February 23, 2017

For Acne "Today I'm starting doxycycline. I was prescribed it because of my cystic acne that only developed because of my birth control I was on. I had the arm implant. The worst decision of my life. I will check back in in 2 weeks to let you know how it worked for me. Please take with food or else it will cause stomach aches."

5 / 10
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  • Mic...
  • Taken for less than 1 month
  • September 4, 2021

For Bacterial Infection "I'm on doxycycline for my 2nd time in just over 1 year, and I've not had any issues with this medication. My reasons for taking it are for a reoccurring infection called MRSA, and it seems that everyone has this, but certain things trigger it, like cigarette smoking and nerves, among other activities, consult your doctor. Doxycycline is pretty simple and straightforward. My doctor said the 1st day to take 2 at once, then follow the next and following days with 2 daily, but take one in the AM followed by dose 2 in PM, and if there are any stomach issues, try eating a small meal or a snack with the pill. Just make sure you're taking the pills close to the same time every time, that'll give you the best results and cause a small build-up to get rid of any infection that's listed. Any side effects or serious effects, see your doctor, other than that, I've never had an issue or side effects with this."

10 / 10
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Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • January 11, 2025

For Upper Respiratory Tract Infection "Completed 2-week 50 mg bid dosage; still occasionally cough up yellowish/green phlegm. Doctor said to take with food to avoid upset stomach, yet one reviewer says doctor told her to take 2 hours before or after food. Hers worked; mine seemingly didn't. Some stomach cramping and constipation."

5 / 10
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  • lex...
  • Taken for 1 to 6 months
  • February 15, 2025

For Rosacea "I was dealing with mild rosacea, mostly cheeks. I was prescribed doxy for 2 months at a 100 mg daily dose. It took about two weeks, and my skin started to improve. I also had to be strict on my diet: very low sugar, no dairy, low histamine foods. I am already a vegetarian. I am at a month of treatment, and my skin looks really good. DO NOT take this medicine on an empty stomach, and if you can add probiotics, do it so you won't have an upset stomach (this medication is really hard on it). I did the mistake of taking this pill with no food, and I immediately threw up. I also use SPF 50 every day. I do not know what will happen to my skin after I stop this medication, but I can honestly say it has helped me tremendously."

10 / 10
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  • jam...
  • Taken for less than 1 month
  • June 30, 2019

For Acne "My experience with doxycycline has been pretty positive so far. It’s been a week since I started, and my skin has already been looking better. There are most definitely side effects, been having really bad stomach issues, kind of makes you drowsy and nauseous. I take it at night so I can just fall asleep with it. In my case, there was a little bit of a purging, but not much. I know that doxycycline is not a long-term solution, but I am really grateful that I was able to be prescribed this medication because my acne was becoming worse and worse."

9 / 10
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  • Nic...
  • January 29, 2016

For Acne "So I am on day 2 of doxycycline. I have had acne for almost a year now, it went from moderate to severe. That's when I decided to go to a dermatologist. So I haven't had any side effects. Eating a big meal and drinking a lot of water with the pill helps from having nausea and stomach aches. Well, I will check in in a few weeks about my progress."

7 / 10
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3 Report

More FAQ

  • Boo...
  • July 3, 2011

For Bronchitis "Very powerful. Works well for the infections, but the side effects are cruel. For an hour and a half after I take it, I have severe nausea, belching with it coming up, and stomach cramps."

6 / 10
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  • Her...
  • October 4, 2009

For Bronchitis "Extreme stomach discomfort and nausea, as well as severe headaches and vaginal itch."

8 / 10
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  • Out...
  • November 20, 2017

For Bacterial Infection "I have been prescribed Doxy for the Lyme disease tick bite. Yeah, it messes with my stomach a bit, but I don't have Lyme disease. I have been bitten and red-circled seven times, NO LYME."

10 / 10
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  • Don...
  • Taken for less than 1 month
  • September 14, 2021

For Upper Respiratory Tract Infection "Severe stomach cramping, stomach pains, diarrhea. They should stick to using it for acne!"

2 / 10
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  • Anonymous
  • November 25, 2009

For Chlamydia Infection "Gave me really bad side effects, upset stomach, diarrhea, migraine headaches."

5 / 10
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  • Kca...
  • Taken for less than 1 month
  • September 19, 2020

For Chlamydia Infection "This drug doxycycline makes me feel nausea, headache, and upset stomach. I feel horrible taking this drug, but I know it has to be taken."

2 / 10
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  • bbb...
  • June 2, 2010

Doxycycline for Acne "It's been pretty good so far. My face has almost completely cleared in one month. I have had no stomach problems."

8 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.