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Dofetilide and Heart Palpitations: What Users Say

Brand names: Tikosyn

Heart palpitations: mentioned by 6 users (7.8%)

Based on user experiences from 77 Dofetilide reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 11.7%
fatigue 9.1%
heart palpitations 7.8%
dizziness 6.5%
tiredness 6.5%
increased heart rate 5.2%
insomnia 5.2%
chills 3.9%
memory loss 3.9%
pain 3.9%

Reviews for Dofetilide

Commonly mentioned side effects
  • Anonymous
  • September 5, 2011

Dofetilide for Arrhythmia "I have been taking Tikosyn for 5 weeks. It did not kick in until they did a cardioversion on me. I am still having high blood pressure and high heart rate, as well as skipped beats. I have a rash and itching that is very bothersome. But other than that, I am doing well. I feel good, but I just wish my blood pressure and heart rate would go back to normal."

8 / 10
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68 Report
  • Mr...
  • March 17, 2016

Dofetilide for Arrhythmia "Experienced CHF in 2010 induced by hypothyroidism, which I had detected 30 years earlier, but doctors couldn't confirm because of outdated TSH standards; also had hypotension and hypoglycemia, which were again medically unconfirmed until 2010 CHF with EF of 13%. Defibrillator implanted in 2010. Put on dofetilide in 2014 by new doctors because other docs had ignored effects of amiodarone on thyroid medication plus amiodarone toxicity. In 2015 had tachycardia of 168; another new doc said dofetilide should have worked, recommended ablation, which was subsequently done. Experienced crippling fatigue; I phased out dofetilide a year later, no arrhythmias, energy returning plus clear thinking. Found ablation effective, dofetilide ineffective plus energy crippling."

5 / 10
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47 Report
  • Slo...
  • May 25, 2011

Dofetilide for Arrhythmia "I have been on Tikosyn for 6 months. The first 4 months were difficult as there were lots of skips and bumps in between episodes of 1-2 per week. Though the times in arrhythmia were getting much shorter. I still feel as though my condition is improving overall, as there are not as many symptoms as before I was taking it. Hope it just keeps getting better."

8 / 10
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64 Report
  • Non...
  • October 20, 2020

Dofetilide for Arrhythmia "I had 9 episodes of arrhythmia 2 hrs and 15 mins after taking. This took 1 hr and 22 mins. I flatlined 7 times, corrected once with CPR, the other six I was paddled. It was my first dose. They were watching, it was pretty bad! Now you know."

1 / 10
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28 Report
  • She...
  • August 13, 2022

Dofetilide for Arrhythmia "61-y old man with paroxysmal Afib previously controlled by Flecainide. Backfired and made Afib much worse during my 3-day hospital monitoring. Tikosyn (500 mcg bid) had a major diuretic effect on me and I went into bouts of Afib up to 11 h long with severe tachycardia 160 bpm."

1 / 10
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11 Report
  • Neg...
  • Taken for 1 to 6 months
  • February 28, 2017

For Arrhythmia "Side effects for me are pain and weakness in the right leg, knee, and ankle. Also, I have had some afib. My INR has been dropping. Also, I'm on Coumadin. I have been on dofetilide for 2 months."

6 / 10
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4 Report

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