Dihydroergotamine and Nausea: What Users Say

• Anonymous
• Taken for 1 to 2 years
• September 24, 2012

For Migraine "Taste in mouth, burning in throat, stuffy nose, and nausea, which all passed after an hour. Medication effective within 60-90 minutes. Very effective and less expensive than a trip to ER to receive DHE intravenously. TAKE A ZOFRAN!"

• ash...
• January 16, 2009

For Migraine "I have migraines usually 3 to 5 times a week, and my neurologist gave me this medicine. I am also taking propranolol and have not noted any side effects. I have found that, for me, it works best when taken at the first signs of a migraine. If I take it when I already have a migraine, it doesn't work. There is a little nausea afterward, but a little food helps. It's a very effective treatment and no rebound headaches."

• Lau...
• October 8, 2019

For Migraine "This is my first dose of Migranal. I just went to a new neurologist this morning, and he gave me a sample. I have a slightly funny taste in my mouth, but I think it's because my nose is stuffed from the Migranal. No signs of the horrible migraine monster yet, and the first signs of it have stopped. I get debilitatingly severe migraine headaches with panic/anxiety attacks. Triptans have not been reliable, and I cannot afford to pay for a trip to the ER that many times a week. So far, so good, nausea and stuffy, but that's a vacation from one of my headaches!"

• Aph...
• Taken for less than 1 month
• April 12, 2023

For Migraine "Used one time during a migraine episode (7 out of ten pain), the pain diminished in about 10 minutes to a 2-3 out of ten. The device/setup is a bit time-consuming but easy to use. However, side effects started immediately with dizziness, unwell physical and mental sensation, as well as severe burning in the nasal cavity/sinuses. I experienced nausea and abdominal pain (7 out of ten) for the next 2-3 hours. I took 25 mg of Phenergan, yet I still projectile vomited 2 hours after the nausea began. I also experienced tingling in my arms and hands with mild to moderate discomfort. My sinuses became congested within the first hour and lasted the remainder of the night. I was unable to breathe through my nose until the following day. The next morning, I awoke with mild nausea, diarrhea, fatigue, and a malaise feeling. Yes, the migraine dissipated and did not return the next day, but the side effects are too much for me to bear. I have had better experiences with other migraine medications, like Nurtec ODT."

• Aph...
• Taken for less than 1 month
• April 12, 2023

For Migraine "Used one time during a migraine episode (7 out of ten pain), the pain diminished in about 10 minutes to a 2-3 out of ten. The device/setup is a bit time-consuming but easy to use. However, side effects started immediately with dizziness, unwell physical and mental sensation, as well as severe burning in the nasal cavity/sinuses. I experienced nausea and abdominal pain (7 out of ten) for the next 2-3 hours. I took 25 mg of Phenergan, yet I still projectile vomited 2 hours after the nausea began. I also experienced tingling in my arms and hands with mild to moderate discomfort. My sinuses became congested within the first hour and lasted the remainder of the night. I was unable to breathe through my nose until the following day. The next morning, I awoke with mild nausea, diarrhea, fatigue, and a malaise feeling. Yes, the migraine dissipated and did not return the next day, but the side effects are too much for me to bear. I have had better experiences with other migraine medications, like Nurtec ODT."

• Mac...
• Taken for 1 to 6 months
• July 30, 2022

For Migraine "I have chronic migraine, and D.H.E. 45 IM has been one of the most effective rescue medications for me. It has helped stop a migraine attack within a half hour (post-injection) for me. I did not seem to experience any adverse effects from this medication but am aware others have noted nausea as a prominent potential side effect. Another plus for me is even one injection (of 1 ml) can often keep a migraine at bay for over a day. Medication overuse or rebound headaches are not as much of a concern with this either (vs. triptan rescue medications). Assembling everything necessary to inject this can be challenging during a migraine attack. It also comes packaged in glass vials; I have found that putting a (Bic-type) ballpoint pen cap over the top of the vial before “snapping” the glass lid off can be really helpful to accomplish this in a cleaner, safer, and easier way. Worth the extra work for me!"

• Nat...
• Taken for 2 to 5 years
• May 25, 2022

For Migraine "Side effects were nausea, vomiting, irritated skin site. Hospitalized for 3 days for 6 IV treatments. Pretreatment is Benadryl 50 mg and Zofran 8 mg. Positive side effects were fewer migraines and side effects of migraines for 10 months."

• Clu...
• Taken for less than 1 month
• August 10, 2014

For Cluster Headaches "Rough side effect profile (nausea, leg cramping, and the injections burn). Have used every day for a couple of weeks to shut down a bad cluster. Worked pretty well."