Dextroamphetamine and Irritability: What Users Say

• Ham...
• Taken for 2 to 5 years
• October 6, 2016

Dextroamphetamine for ADHD "Have been taking Dexedrine spansules (10 mg) for over 2 years, three times per day. I never knew I had rank ADHD all my life - problems with school, the law. I am 47 and have noticed my ambition for life has increased, having more energy. I used to be tired a lot, complaining, generally overall agitated. At the same time, I have many comorbidities to deal with but fortunately don't have to take any anxiety meds. Dexedrine is all I know, and I am satisfied with the results."

• Rev...
• Taken for 10 years or more
• March 10, 2015

Dextroamphetamine for ADHD "I wouldn't use any other type of ADHD medication! Adderall & many of the newer ADHD medications cause agitation & symptoms that make my condition worse. If I didn't use Dexedrine, I wouldn't take medication to treat my ADHD! More people need to educate themselves on how to treat ADHD."

• Mrs...
• Taken for less than 1 month
• September 5, 2015

Dextroamphetamine for ADHD "I am 39 years old and have been suffering from ADD my whole life. It wasn't until recently that I finally figured out what it was. After trying Ritalin, which didn't agree with me, and Adderall XR, which made me irritable, anti-social, and too engaged, I read the reviews of this and decided to give it a whirl. I'm only on week 1, but compared to the others, I am MUCH more myself with no anxiety! Also, I am shocked at how low of a dose gets the job done. I am on 5 mg once daily around noon. You may think you need more, but start low and see how much changes right before your very eyes. You get plenty done and still wind down after 4 hours. I sleep great, and my appetite is only affected the first 3 hours. I didn't give it a 10 because of some memory issues."

• Axi...
• February 14, 2019

For ADHD "Dextroamphetamine IR (or Zenzedi) is hands down the best ADHD medication I have ever been prescribed. I've been on and off stimulants since middle school (25 years old now) and have tried every medication besides Focalin and Desoxyn. Zenzedi is wonderful because not only does it manage my symptoms much better than Adderall, for example, it also does so with absolute minimal side effects. It doesn't destroy my appetite, it's easier to get to sleep at night, it doesn't make me irritable or agitated, and I'm much less jittery and sweaty (as a result of more CNS stimulation and less PNS). I can also achieve the same effect with a lesser amount of medication (2 x 10mg IR vs. 1 x 30mg XR and 1 x 10mg IR). Zenzedi is also surprisingly affordable if you can find a local pharmacy that keeps it in stock. It only ran me $90 before my insurance would cover it vs. $200 for Adderall at Walgreens, which usually won't even have Zenzedi in stock. 100% recommended."

• Axi...
• February 14, 2019

For ADHD "Dextroamphetamine IR (or Zenzedi) is hands down the best ADHD medication I have ever been prescribed. I've been on and off stimulants since middle school (25 years old now) and have tried every medication besides Focalin and Desoxyn. Zenzedi is wonderful because not only does it manage my symptoms much better than Adderall, for example, it also does so with absolute minimal side effects. It doesn't destroy my appetite, it's easier to get to sleep at night, it doesn't make me irritable or agitated, and I'm much less jittery and sweaty (as a result of more CNS stimulation and less PNS). I can also achieve the same effect with a lesser amount of medication (2 x 10mg IR vs. 1 x 30mg XR and 1 x 10mg IR). Zenzedi is also surprisingly affordable if you can find a local pharmacy that keeps it in stock. It only ran me $90 before my insurance would cover it vs. $200 for Adderall at Walgreens, which usually won't even have Zenzedi in stock. 100% recommended."

• ret...
• Taken for 1 to 6 months
• November 20, 2021

For ADHD "I have ADHD with comorbid depression and anxiety, and this is the only drug I've tried that combats all three symptoms at once; SSRIs, SNRIs, TCAs, and other stimulants like Adderall, methylphenidate, and lisdexamfetamine were all ineffective. Methylphenidate gave me anxiety and irritability on the comedown, whereas lisdexamfetamine was barely noticeable because it's a prodrug that is slowly converted into dextroamphetamine in the body. I have zero side effects from this 'dangerous' drug compared to all the SSRIs I tried, which gave me concentration issues, sexual problems, and extreme tiredness. Dex, on the other hand, has given me my life back and is smooth as butter."

• Lco...
• Taken for 1 to 6 months
• March 25, 2016

Dextroamphetamine for ADHD "Dexedrine is okay! When I first took it, I was excited and hoped to feel something. I was instantly in a good mood, more focused, and patient. However, the come down off this drug is horrible. The depression and sadness start to come back, and it's just discouraging that only a medication can band-aid those emotions. I have felt overstimulated as well. I had a gastric bypass four years ago, so my doc said no XR, but he put me on four 10 mg a day, which I feel is too much. I become agitated, irritable, paranoid, panicky, crying, etc. I decreased it to two a day. I feel that this might be too strong of a stimulant for me. I want to try Adderall since it's cheaper on my insurance and it has less dex. We'll see what he says at my next visit."

• Lco...
• Taken for 1 to 6 months
• March 25, 2016

Dextroamphetamine for ADHD "Dexedrine is okay! When I first took it, I was excited and hoped to feel something. I was instantly in a good mood, more focused, and patient. However, the come down off this drug is horrible. The depression and sadness start to come back, and it's just discouraging that only a medication can band-aid those emotions. I have felt overstimulated as well. I had a gastric bypass four years ago, so my doc said no XR, but he put me on four 10 mg a day, which I feel is too much. I become agitated, irritable, paranoid, panicky, crying, etc. I decreased it to two a day. I feel that this might be too strong of a stimulant for me. I want to try Adderall since it's cheaper on my insurance and it has less dex. We'll see what he says at my next visit."