Dexmethylphenidate / serdexmethylphenidate and Irritability: What Users Say

• Soc...
• Taken for 1 to 6 months
• October 13, 2021

For ADHD "My 8 y/o son takes Azstarys for ADHD. He takes his medicine at about 7:30 a.m. Previously, he was on Focalin ER, which was good for about 8 hours, then would completely drop off, so we had to give him a dose of the short-acting Focalin in the afternoon if he was going to need to do anything in the late afternoon requiring focus, like homework or sports. When that wore off, he'd be really grumpy. Now, on Azstarys, he's good all day. In the late afternoon, from about 4 p.m. to 7 p.m., there's a very slow, gradual decline that feels very natural and still allows for him to be adequately functional. Then, by bedtime, it has worn off. Plus, he's eating more! So, big thumbs up for Azstarys."

• JaA...
• Taken for less than 1 month
• May 20, 2022

For ADHD "I’m 35 and am new to ADHD medications. On the first day I took Azstarys, it took about 1-2 hours to feel anything. I remember being quite irritable but have it a couple of days. On day 3/4, I was feeling as irritated, but I remember like a sudden cloudy feeling. So I stopped taking it. Looking back last week when I was trying it for the first time, I can see how I possibly was more productive. I didn’t get everything done, but I accomplished more that week than usual. I have the lowest dosage, so I might give it one more go. I’m still in the process of discovering what works and what doesn’t. I will update when I try it again. Oh, I forgot to mention… on day 3, it only lasted for about 6-8 hours."

• pct...
• Taken for 6 months to 1 year
• June 3, 2024

For ADHD "Initially, the medication was great. I felt focused and could function normally for the first time ever. However, after a few months, I started experiencing a racing heart and hypersexuality, followed by anger and agitation. I would explode over the smallest things. The doctor tried different doses to minimize the afternoon crash. It helped at first, but I still couldn't get past the agitation and anger. In the morning, the medication is effective, but by the afternoon, it's horrible. It's like Jekyll and Hyde – It's wonderful in the morning and all is great, but by afternoon, I'm angry and short-tempered. I think it's time to try another approach and stop taking this drug."