Denosumab User Reviews & Ratings (Page 5)

• MaryAnn
• Taken for 1 to 6 months
• May 26, 2016

Prolia (denosumab) for Osteoporosis "From the start I began to experience side effects. The most bothersome are the extreme sweating episodes followed by chills at least 12 times a day or more. In addition other side effects are more pain in my lower back and hips as well as a rash with associated itch on my upper back. I will never get another Prolia shot!!! Wish I knew there would be so much discomfort!"

• Tilly...
• May 30, 2017

Prolia (denosumab) for Osteoporosis "Three days after receiving my first Prolia injection I developed a cough, which turned into bronchitis & was treated with antibiotics - bad luck, a coincident I thought. A month later my life change with severe bone pain in my right jaw, I had lock jaw 5 times. Pain in my right shoulder, ribs, my neck was so stiff, but worse was my lack of immobility, my morning walk to the bathroom was just like watching Frankenstein walk, I couldn't move any faster because of the pain. Getting on the toilet one off the toilet was a major event. Turning in bed was excruciating and sometimes impossible, this lasted the whole of the summer 2015, which eventually tampered off to where I am today. Worst experience of my life. No more Prolia for me."

• Jjano
• Taken for less than 1 month
• September 12, 2018

Prolia (denosumab) for Osteoporosis "DO NOT TAKE THIS! My grandmother took this needle on a Tuesday, her behaviour changed almost immediately. She became very weak, could not stay awake, her breathing changed and as the week progressed, she got worse. Sunday of the same week her heart rate was jumping between 70 and 120 bpm and her oxygen went down to 90. She was rushed to the hospital and has rashes, water in the lungs, she can't talk because she is so congested and has to be on a special mask for oxygen. She is definitely not the same in a matter of 5 days. I've also noticed she has developed a lot of involuntary movements, all over her body-arms, legs, hands and even eyes. We actually thought she was going to pass away on the Monday after being admitted in the hospital. We were called to have an emergency meeting with the doctor. She only has had one shot and WILL NOT have anymore. Please do your research before taking this needle. Biggest mistake."

• Backp...
• Taken for less than 1 month
• July 12, 2019

Prolia (denosumab) for Osteoporosis "I found that after having one injection of Prolia that the side effects were worse then the possibly of maybe breaking a bone. I had muscle and joint pain, back pain, vertigo, hip pain and just felt flu-ish for more then one month after the injection. I now have diarrhea. I will not be taking it again."

• Helen
• Taken for 6 months to 1 year
• May 13, 2023

Prolia (denosumab) for Osteoporosis "Prolia should be outlawed. Initially, I had severe headaches that woke me during the night. Then fatigue and breathlessness began and increased. My vision became somewhat blurred and I had to visit an ophthalmologist. Then severe, I mean severe, diarrhea began and has lasted now for 4 weeks. My neuromuscular coordination was affected especially my piano playing. I feel unsteady, not dizzy, but unconfident of balance when I walk. This was my first and last shot of Prolia. It really dragged me down. Horrible experience."

• Jas
• Taken for 6 months to 1 year
• June 12, 2019

Prolia (denosumab) for Osteoporosis "I was on Boniva for 10 years with no improvement in my bones. My Doctor switched me to Prolia shots. Took my first shot of Prolia in January 2018 and developed severe mouth ulcers , sloughing of my gums. I could not handle spice or salt and my nutrition fell. At that time I did not associate it with Prolia. I took my second shot in August and my mouth ulcers flared up. Severe ulcers in the gums, upper palate, back of the throat and nasopharynx area. Mouth had grey, purple and white patches. I was unable to eat. I also developed severe jaw pain, bone pain and muscle weakness. For three days my low back , hips and legs froze and I was in excruciating pain and could not walk and was in bed with ice packs and anti inflammatories. I was frightened. I have stopped Prolia. It has been more than a year and my mouth ulcers have not healed. I am now being treated at a University hospital. This is not a safe medicine and should not be prescribed."

• jdlevin
• Taken for 5 to 10 years
• October 13, 2018

Prolia (denosumab) for Osteoporosis "I had been fighting osteoporosis for years when Prolia was suggested. I as on it for about six years. Then a change in doctors at medical center caused a short delay. In a few weeks after that shot was due I had three terrifically painful vertebral compression fractures. Now, eight months later, I'm a semi-invalid in the sense that I cannot be upright (sitting or standing) for more than an hour or two before the pain becomes more than I can bear. I was formerly very active; now my life is extremely confined. The more I learn about this drug the worse I see that it is. My doctor and I have reported this to the FDA. Amgen has no advice as to how to get off safely. "Ask your doctor" they tell me. So far the docs have been unable to show me a safe way to get off this horrible drug."

• Krysa
• Taken for 2 to 5 years
• September 23, 2014

Prolia (denosumab) for Osteoporosis "I have been on Prolia for 2 years. I am so happy. Before Prolia, for a couple of the years I had been on Forteo, and I was tired to shot myself into the stomach every day. Again comparing to Forteo, I have much better results with Prolia. What is the most important for me :) Yes, I have some bones pain (legs, back) especially for the first 2 months but, when I see my last Bone Density results, I can bear the pain :)) Thanks Prolia! God is great!!"

• Kathy
• August 10, 2019

Prolia (denosumab) for Osteoporosis "I decided to take Prolia after being being nagged for several years by my PCP, then my Rheumatomogist strongly recommended and by Neurosurgeon. I did NOT want to take this drug, but I got this shot June 2019. Did not seem to have an adverse side effect until this past week. I could not understand WHY my face and arms felt itchy. Then, 2 days ago, I look at my gums which are feeling tingly. THEY ARE SWOLLEN AND PURPLE RED! I thought it was popcorn I ate a week and a half ago. Called the Dentist who got me in right away and did an ultrasonic cleaning, they saw nothing. Last several nights I have chills with no fever. My eyes are very irritated and extra dry. get bladder instillations 2 times a week because if IC/BPS diagnosed Sept. 2018. Been on IC diet. Everything seems to be under control. No UTIs. Then this past Monday, the nurse found blood in my urine. This is NEW. Lately, I seem to have a more rapid heartbeat- more noticeable."

• Freida
• Taken for 1 to 6 months
• June 15, 2019

Prolia (denosumab) for Osteoporosis "I am 61 years old in general excellent health. After menopause I had issues with insomnia, headaches, lethargy and bad mood. As time went on these symptoms abated. I also began Synthroid for low thyroid function and was feeling better than I had in years. Since taking Prolia one month ago my headaches have returned, I feel fatigued, have constipation and generally in a poor frame of mind. I am sure this medication is good for bone density, but these quality of life issues are not acceptable for me. Will not be taking it again."

• A...
• Taken for less than 1 month
• April 15, 2023

Prolia (denosumab) for Osteoporosis "I was recently diagnosed with osteoporosis in my lumbar spine. I am a healthy, very active, 55-year-old, postmenopausal woman who loves drinking milk. I am on hormone replacement therapy (HRT) and prescription vitamin D. I have been taking thyroid replacement for over 30 years, which could be a contributing factor. The rheumatologist's initial recommendation was Prolia, as she believed it to be highly effective. I received the shot three weeks ago, but I have been experiencing persistent achiness in my bones and muscles that seem to have settled in and worsened over the past two weeks. I have also noticed a significant decrease in lifting and muscle strength, as well as reduced physical endurance. Despite my efforts, I am unable to lift objects that I should be able to and fatigue easily. It is evident that Prolia is not the right medication for me, and I will not be getting another injection. I am too young to allow this disease to progress without taking any action, and I will be exploring other medication options in addition to implementing lifestyle changes and vitamin support."

• Cupcake
• June 12, 2019

Prolia (denosumab) for Osteoporosis "Today is 35-day after 2nd Prolia injection-Side effects began within 48-hours Legs collapse constipation back & muscle pain diarrhea-uncontrollable with accidents fever-sweating at midnight while sitting in front of AC chills-sitting in 90° sun shivering violently severe stomach pain cough-feel like I will suffocate while coughing violently feels like I am drowning at times purple spots on arms and legs severe nausea (I am taking ondansetron 4mg every 8-hours but am sick at 4-hours) feels like I’ve had the flu for 5-weeks Now my left hip and thigh became extremely painful to the point I could not walk or even sit in the car. I am barely able to get around the house, let alone go for a walk. Similar side effects after 1st injection but the first were not as strong and ended in 3-weeks. I did not want to get the 2nd injection but my internist & orthopedic surgeon both assured me the side effects were unusual and I probably would not suffer them a 2nd time."

• Nomore
• Taken for 1 to 6 months
• September 7, 2019

Prolia (denosumab) for Osteoporosis "After one treatment severe jaw and hip pain, rashes & my hair has started falling out. I wasn't told by my Dr I couldn't stop this medication without risking spinal fractures. This drug shouldn't be on the market. I only gave it a one because 0 wasn't an option"

• LStone
• Taken for 2 to 5 years
• April 4, 2017

Prolia (denosumab) for Osteoporosis "I was diagnosed with Osteo in 2010 and was put on Fosamax, along with a daily dose of calcium-VitD. tablet. In 2014 the Dr. changed my prescription to Prolia due to its stronger potency, along with the continued Cal-VitD tablet. Though my bone density increased 10% since taking Prolia, I feel the side effects may out weigh any positive bone density increases. With constant jaw pain, I also have unusual problems with my teeth; constant infections, pain in one tooth or another, and Root Canal Treatments needed. I suffer insomnia, something I never had pre Prolia. With no warning or trigger I have constant blood blisters in my mouth, some as big as 5cent pieces. My cholesterol has increased. I feel unusually tired & have regular leg cramps."

• Cathy
• Taken for 2 to 5 years
• April 29, 2019

Prolia (denosumab) for Osteoporosis "I have had 6 Prolia injections. With the first 5 injections I had muscle pain for a few weeks. This was relieved with Ibuprofen. I had my 6th injection in February 2019. One week after the injection I started experiencing severe hip pain. As the days went on the pain appeared in my shoulders, hands, feet, ankles, knees, and elbows. The pain is so severe I am having trouble walking. It takes me a minimum of 30 minutes to get out of bed. I have been back to my doctor twice and she says there is nothing she can do but prescribe pain medication. She said it will take 6 months for the medication to wear off. I have read comments from some saying even after 6 months the pain does not go away. I have read comments from others saying they have not experienced side effects. You are not safe. Stop taking this drug now. Before this drug I was a healthy active woman."

• lynn
• April 6, 2019

Prolia (denosumab) for Osteoporosis "I had an injection of prolia on Feb. 13, 2019. My health at that time was perfect and I was only taking vitamins for overall health. On the 20th day my blood pressure was high while at a yearly visit to the doctor. On the 22nd day after the injection I went to the ER for visual disturbances, high blood pressure and was told that I was having an occular maigraine. My eye doctor later confirmed that. Before prolia I had not had a headache in over 10 years. On the 26th day my heart began to race and would not stop. This lasted all night. On the 32nd and 33th day after the injection my heart raced for two days and two nights. I went to the doctor and was started on medicine for panic attacks. I had never had a panic attack before the shot. I feel terrible and I don't even feel like myself. I will never take another injection of prolia. I had excellent health prior to the shot and now my energy level is so low I don't feel like doing anything."

• Trish
• Taken for 6 months to 1 year
• September 23, 2019

Prolia (denosumab) for Osteoporosis "I had my 2nd Prolia injection two months ago, the second stage of a two-year research study. Five days ago I woke up with the worst pain of my life, starting in my hip and extending down my leg. Until now, I have been a very active 66-year old, with absolutely no health problems. Oh, how I wish I had never signed on to the study. The osteoporosis that made me eligible to participate was minimal; this pain is atrocious. I trusted the doctor heading the research to, first of all, do no harm. She apparently did not deserve that trust. She did not warn me that I could suffer serious debilitation as a result of Prolia, even after I spoke of a new, nagging hip pain that started after the first injection."

• Joey
• September 27, 2018

Prolia (denosumab) for Osteoporosis "My last shot was May 23, 2015. I am still suffering with muscle and joint pain. Never had vertigo before taking seven shots, I have now fallen 4 times! I cannot say 100% that these were caused by Prolia, but I am 99% sure they were caused by the injections I took. My pains and side effects, sorry to say, have not gone away. I post this hopefully to help others about Prolia. I wish I had known in 2012 before ever taking this horrible drug!"

• G109
• July 20, 2016

Prolia (denosumab) for Osteoporosis "1 shot, due another in August and wondering. Constipation very severe, fatigue, hip pain, upper arm pain and shooting pains in head. I do not know if there are other options available and scared to take second shot in case things get worse."

• Suffer
• Taken for 1 to 6 months
• September 25, 2019

Prolia (denosumab) for Osteoporosis "I was the the same situations with you Kaydee. I lost the trust on DRs. Their concern is only $$$$$$ and your insurance coverage. I cancelled all the appointments. I do my own research on the foods I eat. Try to eat more organic calcium rich balance foods/avoid salty, heavy sugary foods/cut all the preserved foods and snacks. Do gentle exercise as Tai Chi/Breathing Exercises/yoga which helping me great."

• Dagi
• Taken for 6 months to 1 year
• June 6, 2019

Prolia (denosumab) for Osteoporosis "In May 2018 I had my 1st Prolia for mild bone loss. After that I just had an occasional hip pain. Two weeks after my 2nd injection in November 2018 my doctor sent me for physical therapy because of severe lower back pain. The pain moved from the lower back to my thighs. I received a steroid shot into my lower spine without help. 2 months ago I had arthroscopic spine surgery to clean up discs and remove a bone spur. My back healed but the back and leg pains remained. Walking, especially stairs has become an effort, where I used to walk 3 miles daily I can barely walk around the block. My left leg has become weak. Back to physical therapy. Per my surgeon, I should be able to do routine housework, yard work, walking and other low level activities without pain. I truly hope that with time, Advil and a positive outlook the severity of the pain will lessen and I can enjoy life again. One thing I know for sure, I will not get another injection of Prolia."

• Ape
• Taken for 1 to 6 months
• December 20, 2019

Prolia (denosumab) for Osteoporosis "I've been taking prolia for a month and the side effects are horrible. Extremely dry and cracking tongue. Sore throat, acid reflux, prickling sensation in mouth, bitter taste in mouth, back pain, vomiting. I sure do hope it improves my bone density. I won't take it again as these symptoms are quite unpleasant and allow me little sleep."

• NanaKay
• Taken for 2 to 5 years
• May 30, 2019

Prolia (denosumab) for Osteoporosis "I would NEVER try Prolia again. I was not warned at all about possible side-effects. I needed both of my hips replaced and the doctor would not schedule me for surgery until they had improved my osteoporosis. I had undiagnosed hyperparathyroidism. Neither my primary care physician nor the orthopedic surgeon bothered to even read my existing lab work that had been done. I had been on other medication for a year for my severe osteoporosis at 60 years old. My orthopedic surgeon had me get the Prolia shot. Oh my gosh. I have never been so sick with stomach pains. It was like being in the late stages of labor. I finally went to the emergency room and spent 24 hours in the hospital on IV for bacterial colitis. I spent the next two weeks on two different anti-biotics. It was absolutely horrible. Now, I am treating my osteoporosis through nutrition and supplements, no medication at all."

• Annie...
• Taken for 1 to 2 years
• October 1, 2016

Prolia (denosumab) for Osteoporosis "This drug is a life saver. I tried Actonel and Fosamax with poor results. I experienced bone pain and flu like symptoms for weeks on end. After seeing an endocrinologist it was decided I try Prolia. NO side effects at all. Not even soreness at the injection site. I just received my 3rd injection and 2nd bone density test. Density is up 7-8% in spine and hip. I am thrilled."

• musta...
• Taken for 5 to 10 years
• October 5, 2019

Prolia (denosumab) for Osteoporosis "I was diagnosed with fibro (epstein barr) 20 + years ago, so a lot of the side effects from prolia I blamed on that. I have been getting more severe pain (shoulder, arm, wrist, fingers, femur, knees feet, etc, you get the picture) I was in so much pain before the last injection, but was warned about the consequences by the PCP and Endro docs, waited an extra month and felt great so went ahead and had another inject of prolia. I am 4 months in on that and in so much pain I can hardly function. The docs all act like it is worth taking. Boy, they must be getting a bundle from big Pharma!! #NOMOREPROLIA"