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Clenpiq and Vomiting: What Users Say (Page 2)

Reviews for Clenpiq

Commonly mentioned side effects
  • Ber...
  • Taken for less than 1 month
  • January 26, 2021

For Bowel Preparation "I am 54 years old and in excellent health. I followed my doctor's orders leading up to taking this drug and only had clear liquids on the day before my colonoscopy. I took the first dose at noon and drank water as instructed. After 45 minutes, the cleansing started, but so did horrible side effects. I had a severe headache, extreme nausea, vomiting, and weakness. I was in agony for the next 4 hours when it was time for the second dose. I merely took two sips and vomited. I was very sick until midnight (12 hours) only after ingesting the first dose and had to cancel my procedure. It is 5 am the next morning, and I still don't feel well. I don't recommend this to anyone. Not worth the risk."

1 / 10
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  • Mam...
  • July 2, 2019

For Bowel Preparation "This tasted horrible! I could hardly get the second dose down, I was gagging so badly! I followed the directions to the letter and still was not clean, so I have to have a repeat scope in a year. I will be asking for a different prep. I will take Mag Citrate over this any day. The only good thing was the bottles were small, but they might as well have been a gallon since I could hardly get them down. Do not recommend this prep!"

3 / 10
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  • bjp...
  • Taken for less than 1 month
  • November 12, 2021

For Bowel Preparation "Used Clenpiq for bowel prep for my 2nd colonoscopy (1st time use as thought I might tolerate better than other prep). Managed to get the first bottle down holding my nose. The 2nd started vomiting halfway into it. I’m 107 lbs and the same prep is given to someone 300 lbs. It’s cranberry alright with a taste of vomit and Kaopectate and cough syrup. Whenever the pharmaceutical industry finds that TRUE “pleasant” tasting prep, you’ll be richer. Until then, you sell it erroneously. We should be paid to take it. But... it does clean you out."

1 / 10
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Frequently asked questions

  • Lau...
  • Taken for less than 1 month
  • August 14, 2024

For Bowel Preparation "Highly recommended! I had my 10-year routine colonoscopy screening this morning and did the Clenpiq prep last night. The prep I took for my first colonoscopy (GoLightly?) made me so sick — chills, nausea, vomiting — but Clenpiq (like its predecessor Prepopik) made it a relatively painless process — no cramping or nausea at all, and the volume of prep is small and tastes fine, much better than the other stuff. And it did the job, doc said my colon was super clean. Prepopik lets you choose your own liquid as the “chaser” (I find that coconut water goes down the easiest), which is much more palatable than the giant vats of prep you have to drink with most of the other options."

10 / 10
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  • Dad...
  • Taken for less than 1 month
  • February 19, 2019

For Bowel Preparation "I rate this a 1 because of my reaction to the product. I started vomiting within 10 minutes of taking the liquid. I was nauseous and vomiting for the entire night. I then got severe migraines to the point of almost going to the ER. The symptoms lasted well into the following day and even the day after."

1 / 10
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  • Br1...
  • December 14, 2018

For Bowel Preparation "Took the first bottle as prescribed at 4 p.m. and followed with the required 5/8 oz cups of water afterward. Immediately became nauseous. Kept going, but developed a terrible headache, and by the time midnight came around, was vomiting forcefully. Colonoscopy was not successful. Have to repeat next year. The taste is horrendous, and anybody picking up a prescription for this should be picking up one for Zofran (for the nausea and vomiting) in tandem."

2 / 10
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  • Lad...
  • June 16, 2021

For Bowel Preparation "I had my 8th colonoscopy today, and I must admit this was the best prep I've ever used. I went on the all-liquid diet yesterday morning and took my first dose at 5 p.m. last night. No nausea, gagging, or cramping. I had a slight headache. The prep took about an hour to kick in. I went to the bathroom off and on until midnight or so. I took the second dose this morning at 7:45 a.m. No problems handling this either. By the time I was ready to head to the surgicenter at noon, the remainder of my output was clear! My colonoscopy was negative, and the pictures of my colon were bright and shiny! I told my GI doctor about my experience with this prep. He was happy to hear that I had no problems. As noted by the others here, the prep is expensive. I had a coupon from my doctor and, with insurance, ended up paying $75."

10 / 10
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  • SCa...
  • Taken for less than 1 month
  • November 9, 2018

For Bowel Preparation "Used the day-before protocol for my first colonoscopy scheduled for this morning. Took the first dose using a straw yesterday at 5 pm. The taste was a little nauseating, so I sucked on a lemon to help get it down. Felt a bit queasy on and off at first, but figured it would pass. Within an hour or so, the diarrhea started. But then, by the second hour, I was so nauseous and began vomiting. Couldn't even stomach a sip of water, so I was unable to follow the protocol of drinking 5 glasses before the next dose scheduled for 10 pm. Felt very weak. Couldn't take the second dose and couldn't even drink an ounce of liquid until after 1:30 am. Needless to say, I had to cancel the procedure. Horrible experience."

3 / 10
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  • Mar...
  • Taken for less than 1 month
  • May 8, 2022

For Bowel Preparation "Horrendous experience. 2nd dose of Clenpiq gave me a bad headache, nausea, and projectile vomiting. My colon was not cleaned, and now I have to have a repeat colonoscopy. Now experiencing persistent cramping and diarrhea."

1 / 10
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  • Old...
  • May 21, 2022

For Bowel Preparation "Clenpiq worked too well. The bowel movements were explosive and uncontrollable. I couldn’t make it to the bathroom. I vomited up the second dose at 4:00 am but was still prepped well enough for the procedure. While it was easy to drink, I wonder if it is too potent for an older woman."

6 / 10
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  • Anonymous
  • January 27, 2022

For Bowel Preparation "Felt like I should contribute here since I came here before my prep to hear about other experiences with Clenpiq. Bottom line - very easy and smooth. I was very apprehensive and anxious about how I’d tolerate it and was very pleased. I ate a pretty simple diet 2 days before the prep, which may have helped? I also hydrated a lot during the day of the prep. First bottle at 6 pm (started at 5:50). Held my nose, sipped with a straw, chased it with lemon Gatorade, and then sucked on a lemon and barely tasted it. I used the full hour to take down the bottle and drink the 5 eight-ounce cups of water. Had first bathroom run at around 8 and then around 9. Second bottle at 11 pm. Went down just as easy, same method. Bathroom twice after that. Slept about 4 hours. Got up at 6 am to shower. Went again and got to appointment at 7 am. It really was easy. No gagging or nausea. Just felt a bit raw after so much time in the bathroom!"

9 / 10
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  • Cor...
  • April 5, 2021

For Bowel Preparation "I just drank my first bottle about 15 minutes ago. I had to chase with Gatorade, though it didn’t make much difference. Left a horrible taste in my mouth, and I had to run to the bathroom right after because I thought I was going to vomit. I’m prepping for my 4th colonoscopy. I would’ve rather taken Miralax! Don’t take this stuff if you don’t have to, it tastes bad and was very expensive. ($30 for 2 bottles - 160 mL) Not sure how it’ll work, but vomiting isn’t in my plans today!"

4 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 16, 2022

For Bowel Preparation "I found the product to be easy to use. It wasn't as nasty as the other prep solutions, and at least I could get it down without vomiting. My biggest difficulty was opening the bottle. I have RA and live alone and had to have a neighbor open the bottles. I strongly suggest that the packaging be modified."

9 / 10
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  • Lor...
  • Taken for less than 1 month
  • April 9, 2022

For Bowel Preparation "I was absolutely terrified and a wreck with worry for 2 weeks before the colonoscopy. It was all for nothing. Clenpiq is amazing. I didn't think the taste was bad at all. I followed the directions to the letter and had NO nausea, cramps, or vomiting. It was gentle and barely fazed me. Several trips to the bathroom, not super urgent, flushed me out completely. The first bottle took 90 minutes to 'kick in,' and the second bottle took about an hour. Colonoscopy itself went great, hospital staff was super nice, I have no recollection of it -- came out of anesthesia feeling good. The worst part of the entire thing was the liquid diet the day before -- I was starving and weak but got through it. I know everyone's different, but for me, Clenpiq was truly a miracle drug, and I will definitely use it without hesitation if I have to do this again. Insurance partially paid, and my cost was $50. So worth it!"

10 / 10
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  • Mar...
  • Taken for less than 1 month
  • July 30, 2021

For Bowel Preparation "It’s 3:45 AM, and I am gagging on my second bottle of this! The company has got to come up with a better taste because there’s no way this tastes like cranberry. The first bottle was hard enough. I have tried using a straw, and it doesn’t help. I have tried squeezing lemon juice in my mouth after each sip to no avail. I wish they hadn’t discontinued Prepopik. That was the best prep."

6 / 10
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  • Sic...
  • Taken for less than 1 month
  • April 28, 2021

For Bowel Preparation "Within an hour of drinking that nasty stuff (worst taste of any prep I've ever drank), I puked my guts out. Was sick all night. Had to start the second bottle at 4 a.m. I took the first drink and puked again, then every drink after. I had to reschedule my colonoscopy because I never went poop due to puking it all up! Would never use this product again!!!"

1 / 10
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  • Ash...
  • November 5, 2020

For Bowel Preparation "I chose a prescription for Clenpiq vs. Miralax/Gatorade, and I wish I had not. I did not mind the sweet/salty taste much for the first bottle. Started at 6 pm, drank about 48 fl oz of water within a few hours, and had one bowel motion (BM) at about 10:30 pm. Then it got bad! I woke up at 4 am to take the second bottle, and my whole body was extremely fatigued, and my joints seemed achy and head foggy. I had nausea, stalled on the second bottle, and suddenly vomited at about 4:30-5 am, which severely burned my throat. I could not go back to sleep and tried getting the second bottle down at 6:30 am but threw it up within 5-10 minutes. I wish I had gone with the non-RX Miralax/Gatorade prep!"

2 / 10
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  • BcO...
  • Taken for less than 1 month
  • June 16, 2022

For Bowel Preparation "1st colonoscopy and was terrified of the prep, but it was pleasant. I'll break down my review by taste, dose 1, and dose 2. Taste: Loved it. I don't understand the bad reviews about taste or why people need a straw or to sip on a lemon. I did not need those. The cranberry taste was great! My suggestion for your 1st time: Test it out by first taking a sip without the straw or lemon. Also, some people refrigerate it to make it taste better. It cannot be refrigerated. It tastes fine warm, a little salty taste, but 90% sweet. Dose 1: This was harder for me of the 2 doses. I finished the bottle within 30 mins, started pooping 15 min later, and then pooped for 4 hours. I got nauseous, threw up, had a headache, and had bad sweats, but that's not Clenpiq's fault. Those are normal side effects of any prep. Don't blame Clenpiq. Dose 2: Started at 6 AM. Bottle done by 6:30. Clear liquids done by 8:30 AM. No side effects! Really pleasant. Result: My diarrhea was yellow as expected. The colonoscopy went well."

10 / 10
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  • Whi...
  • Taken for less than 1 month
  • February 6, 2025

For Bowel Preparation "Four days before my colonoscopy, I ate only non-fibrous foods. The day before, I switched to a clear liquid diet. At 9 PM, I took my first dose of Clenpiq. Two to three hours later, I experienced a violent, explosive evacuation, barely making it to the toilet. The pain was excruciating, and I felt delirious, nauseous, and on the verge of calling emergency services—though I couldn’t reach my phone. Eventually, the pain and symptoms subsided. At 3 AM, I hesitantly took the second dose, fearing another traumatic reaction. I drank the 2nd dose followed by 32 oz clear liquids, including broth, water, and green tea. Surprisingly, there was no severe reaction—just a steady flushing of water. No vomiting, no delirium, no extreme discomfort. I felt fine afterwards, but not sure if this was the best way to clean the GI for the colonoscopy."

8 / 10
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  • Lau...
  • Taken for less than 1 month
  • August 12, 2021

For Bowel Preparation "I was nervous about taking this prep for the taste since I’ve done this multiple times. What I wasn’t prepared for were the side effects! I’m 5’4 and wondering if even the one bottle was too much for me. Within twenty minutes of taking, I was throwing up violently and lost consciousness. Luckily, my boyfriend was home because he had to hold me up while I puked, and my vision was completely black! Horrific experience. Definitely did what it was supposed to, but I have never been so scared in my life. I thought I was having a seizure at one point!"

1 / 10
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  • Juj...
  • Taken for less than 1 month
  • March 13, 2023

For Bowel Preparation "Drank liquids before and after the Clenpiq as directed. Within 15 minutes, I had projectile vomiting and an extreme migraine. Could not continue with prep. Need to find something else."

1 / 10
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  • Anonymous
  • August 5, 2022

For Bowel Preparation "This is by far the worst liquid a human can ingest. I vomited from the nausea it caused. I don’t even know if I can make it through half of the 2nd bottle (bariatric patient - 5 years out)."

4 / 10
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  • Aja...
  • Taken for less than 1 month
  • August 16, 2021

For Bowel Preparation "It was simply awful. It’s sickeningly sweet. I had violent vomiting following the second bottle, even though I drank a lot of water. I vomited all the way up to my procedure. Never again!"

2 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.