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Wellbutrin User Reviews & Ratings (Page 2)

Wellbutrin has an average rating of 6.8 out of 10 from a total of 757 reviews on Drugs.com. 58% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Wellbutrin

Commonly mentioned side effects
  • Anonymous
  • Taken for 1 to 2 years
  • October 26, 2021

For Depression "Made my anxiety way worse. I was argumentative and mean. Very emotional all of the time and made my PMS symptoms worse."

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  • E18...
  • Taken for less than 1 month
  • October 23, 2021

For Major Depressive Disorder "Although I hoped it would work (I had Wellbutrin XL), it resulted in sharp chest pain, tight chest, and blurred vision about 2 days after starting, and 5-6 hours after the dosage. The next few days I was on it, the effects became worse, including terrible mental effects (although I am an 18-year-old male, and I knew that as it had a black box warning, it had a possibility)."

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  • Sar...
  • Taken for less than 1 month
  • September 9, 2021

For Depression "I’ll start by saying that these types of drugs work differently for everyone, so keep that in mind!! I have severe OCD (intrusive thoughts) and anxiety, along with minor depression. I was prescribed Wellbutrin to give me a better “overall sense of well-being.” I knew going into this that it takes a while and there can be adverse side effects. Simply put, this drug sent me into a deep spiral. It made my response to intrusive thoughts worse, I had intense nightmares about my intrusive thoughts, and it made depression enhanced. I remember I would wake up every morning with a tight feeling in my chest because I was so anxious!! I had several panic episodes (one in public and another at home). Overall, I just had a sense of hopelessness that things wouldn’t get better. I also could not be alone as these side effects got worse when I was alone. I know this drug works well for some people, but it did not work for me."

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Frequently asked questions

  • Wel...
  • Taken for less than 1 month
  • September 2, 2021

"My husband went to our doctor for anxiety, and the doctor told us that my 35-year-old husband was bipolar and put him on Wellbutrin XL. After 6 days, he was being another person! Raging, paranoid, delusional, not the man I married and share a child with. We called the doctor and complained of the side effects, including the scary delusions he was having, and I reminded the doctor of my husband's family history of suicide. The doctor said that the Wellbutrin XL protocol was to double the dosage, and he would see us again in 12 days! The next day, my husband shot himself on our couch!!! My first cousin, raised as sisters, was committed against her will for suicidal thoughts while on Wellbutrin XL!! PLEASE BE SAFE!! IF YOU HAVE ANY ODD SYMPTOMS, STOP TAKING AND GO TO THE ER!"

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  • Ray...
  • Taken for less than 1 month
  • August 20, 2021

For Depression "When I first started taking 150 mg of Wellbutrin, the first 4 or 5 or so days I literally couldn't sit still after taking it. I had to do something, anything. I'd say I was borderline manic. Then, after that point, it just stopped working. Now I find myself sitting in the same spot for hours, not realizing how much time has passed and not having the will to do much of anything. Not to mention, it feels like I've stopped thinking, like there is a fog in my head. Other meds I've taken/am taking (like Zoloft) do not have this effect. Would not recommend."

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  • Kat...
  • August 20, 2021

For Depression "150 mg XR. I have low dopamine, so I thought this would be awesome for my ADHD. Wrong! The first week was AWESOME. I felt more awake, motivated, and less hungry. Cool, right? Week 2, I started getting a little irritable... maybe because I couldn’t freaking sleep! I've never had sleep issues EVER until this. By week 3, I was extremely manic. Horribly paranoid. I had racing thoughts that wouldn’t stop. I am going through a divorce, so you can imagine all I wanted to do was GO INSANE because of my hatred for this man. It was not manageable on this medication. I was so thirsty, my head felt like a balloon, extremely confused and forgetful, most awake I've ever felt, couldn’t breathe right, constipated. Went to the ER... they didn’t do ANYTHING. The medical field is an absolute joke. Also, I was BREASTFEEDING… I was told it would not affect my baby. Ha!!! As soon as I stopped the meds, she stopped crying, started sleeping again, and regular poops again."

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  • Boo...
  • April 2, 2021

For Depression "Before taking Wellbutrin, I was on Zoloft, which made me really tired, and I had no motivation, so my doctor put me on Wellbutrin 150 mg. The first couple of weeks taking it, I was sick from coming off Zoloft and didn’t feel any better depression-wise, I was much worse! After a few weeks, I felt better, but felt it didn’t help my moods and anger like Zoloft did. After being on it for 2 months, I have started feeling sick, my head feels like there’s so much pressure, my heart pounds a lot, I start to feel weak. I went into the ER because I had bad stomach pain and diarrhea, I was sweating and shaky. I am calling my doctor to see what my options are. At this point, I don’t want to take any medication because I feel like rubbish."

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More FAQ

  • Ben...
  • Taken for 1 to 2 years
  • March 18, 2021

For Depression "I have been taking Wellbutrin for a year, and my depression is still there, as bad as ever."

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  • Ean...
  • January 31, 2021

For Depression "I took generic Bupropion 150 XL from Dr. Reddy Pharmaceutical for 10 days. My doctor said there were no serious side effects. I might have dry mouth, she said, but it'll help with your loss of energy. The first two days, I certainly had dry mouth (and increased urination), maybe a little more energy, but on day 3, I started experiencing flu-like symptoms, awful body aches, diarrhea, vomiting, profuse sweating. I felt terrible! To make matters worse, my normally low heart rate (around 50 beats per minute) skyrocketed to 130-140. I felt delirious, and I immediately went off of it. I almost went to the ER, but I decided to stay home and monitor my own symptoms as I'm in healthcare myself. Currently, day two off of it, but I am still experiencing flu-like symptoms and now eye pain with dizziness. Thankfully, my heart rate is slowly going down. My biggest concern is with people who have high blood pressure. Do not go on this medication. Try a different one. These side effects are not worth it."

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  • D S...
  • Taken for less than 1 month
  • January 29, 2021

For Depression "Since when it comes to this type of medication, it works like a dream for one and a disaster for another, I rarely read these reviews. I have never left one either. But my experience with this one was not good. Hopefully, for those who experienced sickness, hard depression, whacked anxiety, dizziness, sick headaches, sleeplessness, zero appetite, head pressure, and pure insomnia, maybe this review will give you hope as you are not alone. I was going to try to get through it, but no way. Garbage. After 1 week, I bailed out. Purely awful for me."

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  • Gra...
  • Taken for 1 to 6 months
  • January 17, 2021

"I personally had a horrific experience with this drug, which was prescribed for anxiety and OCD. I had migraines, itchiness all over my body to the point I scratched myself bloody, insane stomach cramping, I couldn’t even think about food or I would literally gag. I couldn’t eat without feeling like I was going to full-blown puke after. I was super shaky, had really bad outbursts of anger and sadness, and my depression has never been worse. The suicidal ideation was powerful and never made me feel so depressed in my life. I wasn’t getting out of bed unless I had to use the bathroom. This medicine personally debilitated me, and if you have issues with being a person that always gets every side effect (like me), I would highly recommend steering clear!"

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  • JDa...
  • Taken for 6 months to 1 year
  • January 8, 2021

For Major Depressive Disorder "I am an (older) teenage girl who has struggled with mental illness my whole life, and I’ve been on many medications, and my least favorite is Wellbutrin. It caused my anxiety to worsen, made me constantly dizzy and shaky. I would lose control of my eyes, and they would roll into my head several times every hour, and it actually made my eyesight worse (sounds unlikely, but it’s true). I wouldn’t recommend this drug to anyone."

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  • Tga...
  • Taken for less than 1 month
  • January 4, 2021

For Major Depressive Disorder "Made me extremely suicidal."

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  • Raq...
  • September 24, 2020

For Depression "This medicine, Wellbutrin, just made me sleepy and irritable/depressed. Didn’t have any side effects like dry mouth or excessive energy. It kinda made my depression worse. Keep looking for the right med. It works for some, but unfortunately didn’t work for me."

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  • Joy...
  • Taken for 1 to 6 months
  • September 2, 2020

For Major Depressive Disorder "I’m a 39-year-old female who was prescribed Wellbutrin/Bupropion without a psych evaluation, and as soon as I started taking it, I began having dreams and sexual desires. I continued thinking things would change, but they got worse. Weeks later, I began to hallucinate and even forgot where I parked my car after going shopping one day and ended up calling the police and reporting it stolen when it wasn’t. I also started seeing things that weren’t there and having really dark thoughts. This drug took over my life and caused me to make irrational decisions, like up and moving 1,200 miles across the country for no apparent reason whatsoever. A situation I regret! I got a second opinion and was taken off of Wellbutrin immediately and given a psych evaluation. I was given Prozac and Trazodone but no longer take them. I just got a puppy, I changed my diet and lifestyle, and learned coping mechanisms. I will never take another pill if I can help it."

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  • JSa...
  • Taken for 1 to 6 months
  • August 13, 2020

"I was prescribed Wellbutrin 300 mg while receiving treatment in a psychiatric hospital. At the time, I was on 3 other psychotropic medications. I didn’t notice any changes for about 8 days. From there, I developed treatment-resistant insomnia unrelated to bipolar. I was prescribed around 10 different medications for sleep, none of which were effective. Because of the length of time after being prescribed Wellbutrin and having used it in the past without issue, we weren’t able to identify the cause of my insomnia. Before seeing a neurologist, I decided to taper off as a last effort, as that was the only change within the past several months. It worked, and after 1 1/2 months, I can sleep for more than 2 hrs a night! I would say Wellbutrin is effective for many, but not only did it cause insomnia, but also weight gain, unlike a lot of other reviews I’ve read."

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  • Jan...
  • March 7, 2020

For Depression "DO NOT TAKE THIS IF YOUR PRIMARY ISSUE IS ANXIETY. I got on this medication because I was having trouble with anxiety and insomnia. My NP wanted to start me on Wellbutrin 150mg XL and I kept reiterating to her that I have no depression whatsoever, I’m just anxious, but she said it would help. Within 2 weeks, I was so nauseated, in a complete brain fog, my anxiety got so much worse, my heart would race, I was having panic attacks daily, couldn’t sleep, my mind was racing non-stop, and although I’ve never felt as if I had issues with depression, I was so depressed on this medication! I went from being very high-functioning with mild to moderate anxiety to completely useless on this medication. I called into work multiple times (which I had never done before - I’m a nurse). I couldn’t focus, was so disoriented, and felt like I was just floating. I stopped and feel much better after a few days and I got on a PRN benzo for anxiety."

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  • ctr...
  • Taken for 1 to 6 months
  • February 4, 2020

For Major Depressive Disorder "After 1 week of taking Wellbutrin, I developed severe intrusive tinnitus. I have been off the drug for almost a year, and it has not faded at all. While obviously this side effect doesn't happen to everyone who takes Wellbutrin, it is frighteningly common. All of the doctors I've seen since then (psychs, ENTs, etc.) weren't surprised at all when I told them my tinnitus was from Wellbutrin. It has absolutely destroyed what was left of my life. I already had depression, anxiety, and insomnia, now all of these are 100x worse, plus suicidal thoughts. Again, I don't want to say 'don't take this drug' because all drugs have side effects, and I was one of the unlucky ones. But I would highly suggest something else as I would not wish this on my worst enemy."

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  • Anonymous
  • February 3, 2020

For Depression "I totally agree with the dad who took this horrible medication. It was a complete and scary nightmare as it gave me insomnia, “sudden fear,” that I NEVER HAVE! These pharmaceutical companies and the psychiatrist out there are so unclear of the severity of what they prescribe to people! Thank goodness I can be my own advocate. The dad who also shared here can be his own advocate, we survived the damage these drugs can do to one’s mind. Everything stated here is my personal experience and opinion. They don’t do enough research before allowing these drugs on the market."

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  • flu...
  • Taken for less than 1 month
  • January 24, 2020

For Depression "I was put on Wellbutrin for depression and had violent, psychotic episodes out of nowhere. Was delusional, convinced that people in my life were out to get me, were spies, that my pet kitten was evil. When people tried to calm me, I saw them as menacing and would physically lash out. I went to my doctor and was told that I was lying about this... I'd never had psychosis before or after the medication. Only on it."

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  • Use...
  • Taken for 6 months to 1 year
  • January 23, 2020

For Major Depressive Disorder "Does nothing for depression. Dried me out to the point of needing steroid eye drops and regular eye drops every 4 hours. I would also wake up every night with a dry mouth. Don't take if you have insomnia. More of my life wasted trying potions."

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  • Wan...
  • Taken for 1 to 6 months
  • December 27, 2019

"Was on Wellbutrin for 4 months for visceral hypersensitivity. Made me cry every day. Made my heart race. Felt lightheaded and confused. Could not form words. Exhausted but revved up. So much better since I stopped."

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  • Jod...
  • Taken for 1 to 6 months
  • November 6, 2019

For Depression "Wellbutrin made my depression extremely worse. Cried every day since starting it. Also made my anxiety worse. Definitely not a good drug for me."

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  • Kac...
  • Taken for less than 1 month
  • October 29, 2019

For Depression "Gave me horrible headaches, flu-like symptoms, horrible rash, and severe depression. I literally felt toxic on it. I’ve heard this drug can be very dangerous, and I see why! Got off immediately, or it would have destroyed all my relationships and myself. Also caused anxiety attacks. Be very careful with this drug!"

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  • Mar...
  • Taken for less than 1 month
  • October 17, 2019

For Depression "I have been on antidepressants for decades. My P.A. put me on Zoloft, and I took it for months with no effect. I asked to try Wellbutrin, as it helped me back in my 30s. Been on it three weeks. I CANNOT explain how bad the anxiety is. I cannot sleep. I cannot speak well, nor can I remember words or their spellings. Let us not mention that sudden feeling of rage and anger. Decided to do some research and find other people's experiences, and here they are. Many with the same issues. Perhaps all of this would dissipate over time, but I can't live like this. I will discontinue using it, and I hope that this helps someone. Please keep fighting, NEVER give up. I'm going to keep searching for the right cure for me."

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.