Wellbutrin and Headaches: What Users Say (Page 2)

• qua...
• Taken for 1 to 2 years
• August 4, 2012

For Depression "When I first took it, I thought it was great, but after being on it awhile, I got terrible headaches, and if you ever got angry while on it, my blood pressure went real high."

• Anonymous
• August 11, 2011

For Anxiety "Have only been taking for three days. Have some headaches, nausea, no big deal. I don't like the feeling after my second dose at night. I have gotten panicky and felt like I was going to have a panic attack, but have not so far. I am mainly using this to quit smoking, and I see that it is triggering my anxiety somewhat, but I have already lost the urge to smoke and will quit on my quit date. I would rather deal with side effects for a couple of weeks than die of lung cancer and leave my children with no mother. Especially after losing my mother at a young age and my grandfather. I am hoping this will help my depression and anxiety after I am used to it. I can't wait to be smoke-free soon."

• Cma...
• December 3, 2016

For Major Depressive Disorder "I have been taking this medication for about 2 weeks now. I got prescribed it in the hospital after a fallout. I tried Prozac while in high school and had no luck with it. Then was prescribed Zoloft a few months ago and obviously didn't work, considering landing myself in the hospital. Now trying Wellbutrin. Even though I have just started it, I'd say that I do see some positive effects in it. I have more motivation and am trying to do better for myself. But I do have some side effects including really bad headaches, ringing in ears, insomnia, dizziness at times, with nausea. I also have noticed that taking Excedrin to suppress the headaches doesn't help but makes my anxiety increase. Don't take a dose late either as that just increases mood swings."

• jmm...
• April 15, 2015

For Depression "I was diagnosed with severe depression and anxiety, as well as a bit of OCD regarding my weight well over 10 years ago, but started taking medication for it only 2 years ago. I'm on Wellbutrin again, after a year or so off of it, for about 6 days now, and I haven't felt much of a positive change whatsoever, unfortunately. The one side effect I've been getting is extreme migraines. I suffer from chronic migraines anyway, but they're never usually this bad every day. I'm not sure if it's because I'm still coming off of the Zoloft while starting up the Wellbutrin. Zoloft gave me awful headaches and major weight gain along with some insomnia. I'm sticking it out and hoping that the migraines go away. I have been nauseous daily also."

• Bri...
• November 20, 2014

For Major Depressive Disorder "I'm male, 54 years old and weigh about 180 lbs. The first time I tried Wellbutrin, it was 150mg twice a day. It was too much for me. Side effects: Jitters, hyperactive, constant bouncing of knee when sitting, clenching teeth, weight loss, tinnitus, insomnia, dull headache in back of head. I decided to quit Wellbutrin but recently resumed using it. I only take 75mg in the morning (5 AM) then 75mg at 11 AM. They are the 'SR' type. I will continue using this dose until my body adjusts and then I may up the dose to 150 twice a day. For me, starting at 300mg a day was far too much. I believe starting lower, I will be able to remain on this."

• Anonymous
• January 19, 2011

For Depression "Just started taking this for depression/anxiety, so far, so good. The first few days, I could definitely feel the stimulant effect, but on day 5, I can barely feel anything. Obviously, it's too early to tell how it will help with anxiety/depression. I had just a hint of a headache, but nothing bad enough to even take anything for. No real trouble sleeping. I will be increasing the 150 mg to 300 mg (twice daily) Saturday, so I'm sure there will be another adjustment period then. I've heard it's important to take the second dose fairly early in the afternoon (around 3 or 4), so it doesn't keep you up. At first, I did not think this would work with my anxiety, but it's mostly gone due to my body adjusting."

• Anonymous
• October 23, 2010

For Sexual Dysfunction, SSRI Induced "I was put on 100 mg Wellbutrin for PMDD issues and stayed on it for about three years. I ended up having many side effects, such as added anxiety, horrible headaches, and constipation. I also lost some weight. However, the mood swings stopped, and I have to say sex was never better. It added to my sexual response for sure, and I really miss that part. If not for the constipation and heart flutters, I would have stayed with it."

• Fai...
• Taken for less than 1 month
• November 27, 2021

For Depression "I am on week 3 on Bupropion 150 SR, I went off Paroxetine cold turkey and started this. First week, I was tired all the time and had some weird nightmares that went away starting the 2nd week. Then the 2nd week, I felt awkward. I was not myself, I was very irritable, didn't want to be around people, had some headaches that week, and wasn't interested in doing many things. I was about to quit, but my doctor told me to please give it a try until week three when it is supposed to start working (from week 3 to 6). So I did with a lot of effort, and I am so HAPPY I DID HANG IN THERE!! I FEEL SO MUCH BETTER. Today is my day 22, and I at last feel peace, joy, and motivation again to do things I didn't want to do before. I am eating less, not so hungry, stopped smoking, and do not need caffeine to function as I did before. It doesn't have side effects on libido like Paroxetine. So far, it has been worth the wait of 3 weeks of not feeling so well. IT IS WORTH IT. PLEASE HANG IN THERE!! Pray for all to feel happy."

• Sun...
• Taken for 1 to 6 months
• August 8, 2021

For Depression "I have found Wellbutrin to be the best for me. I've tried Zoloft, Lexapro, Cymbalta, Adderall, Vyvanse, Prozac, and Strattera. These others made me too agitated or too zombie-like. No dry mouth, no jaw clenching, no yawning, no RLS, no anxiousness, no headaches with Wellbutrin/Bupropion. Feel uplifted, more my old self, laugh and love easier, and anxiety a bit better. Less achy too! My long-term memory has even improved. I don't mind the vivid dreams, kind of fun. I do have some side effects which make me wish and plead for a lower dosage to be available. I'm taking 150 XL here in the USA. I really wish they'd make a 75 XL for sensitive types like me. I often get into a hyperfocus mode with this dosage of Wellbutrin. I can get a ton of reading done, internet research, etc., but then procrastinate things of higher priority. Please, manufacturers, please offer 75 XL as well. I think you'd be helping a ton of people."

• Ddd...
• Taken for 1 to 6 months
• February 29, 2020

"Aside from the minor headaches and nausea, my experience has been better than most of the recent reviews. I started on Lexapro several years ago, but the sexual side effects were just too much for me compared to the minor effect it had on my well-being. I've had none of that with Wellbutrin, and I feel much better. I've lost approximately 35 lbs since starting, though I've also changed my diet and exercise patterns. My brain is no longer a swirl of indistinguishable thoughts, and I'm able to focus for more than a second at a time."

• Bip...
• Taken for 1 to 6 months
• March 12, 2019

For Depression "I have bipolar II, and after a series of failed drugs, I was prescribed quetiapine (that's a whole other message board) and bupropion. I was on Activas bupropion 150 XL for about six weeks. It stabilized me, but I was still depressed - but functioning. Side effects - waking up early, feeling like a zombie, loss of appetite - went away within that time period. I've now been on Par Pharmaceutical's bupropion 300 XL for about a month. Side effects are irritability and jitters, but I'm hoping those go away. I tried Activas 300 XL - oval pills - and it seemed to dump a large portion of the medication about two hours after taking it, giving me a zombie effect. It also gave me a headache. Those things may have gone away with time, but I switched back to Par. Overall, I'm content, and my depression is gone."

• Lad...
• Taken for less than 1 month
• February 5, 2018

For Depression "Started bupropion XR 150 for depression and ADD. Took it once in the morning at 8:00 a.m. for only two days. On the first day, got very sleepy two hours after taking it, I got a mild headache and very sleepy at night, slept okay, crazy dreams. Second day, no headache, felt no energy but just drive to do whatever needed to be done through the day, dishes, laundry, etc. Second night, I began to itch. My arms, back, top of head, and noticed my asthma started to flare up. So I decided to discontinue use in fear of allergic reaction. Did not want to have a major reaction or get the welts and worse rashes I’ve heard of. So far, took last dose on a Thursday and today is Monday, so four days off. No major withdrawals or signs, but I just feel really good as the days go on. Did the two days knock my brain out of depression? Hopefully, I can add more comments in a few days to see what happens within the next week and so forth."

• Rep...
• Taken for 2 to 5 years
• March 6, 2015

For Major Depressive Disorder "Coming from a very problematic childhood, I've been labeled everything from A to Z by psychiatrists and given a slew of meds. Wellbutrin, in my experience, has been beyond beneficial. At first, for the first week or two, I had slight tremors, irregular heartbeat, major insomnia, and headaches, but I dismissed them. I still have slight insomnia, which is why I take them when I wake up. But reading comprehension, multitasking, thought focus, and moods overall have dramatically improved! I'm one of those people that may have to take them for the rest of my life, but I'm not complaining =). One thing that does bother me, though, is dry mouth from Wellbutrin, but I take Biotene, which helps a bit. Enough to make it worth it anyways lol."

• Anonymous
• December 10, 2012

For Depression "I was first prescribed Pristiq and found it to seriously affect my interest in sex. I was then switched to Wellbutrin. I have been on this medication for 2 months now. At first, I had severe headaches and almost gave up. I'm glad I didn't because I am feeling much better. I do find it hard to sleep some nights, but hopefully that too will pass. I also feel nausea occasionally. My moods seem much better, negative thoughts creep up but quickly go away, and I feel more content. I am currently on 150 mg."

• Anonymous
• April 29, 2012

For Depression "I started off on the Wellbutrin 150 mg XL twice a day, and I was exhausted every day, not to mention the nausea was so bad I had to stop taking it. Just started on Wellbutrin immediate release at 100 mg once a day, and it is a complete difference. I have so much more energy and focus, so far I love it. I do get a little headache by the end of the day, but it's not a big deal."

• Rid...
• Taken for 1 to 2 years
• February 21, 2021

For Depression "Anxiety was a way of life, but now my Dr. prescribed 150 mg time-released. Flowers for Algernon and enhanced sex drive all in one. My work performance hasn't been this good in years-I'm near the end of my career, and I'm sharp and concise as ever. Hot Wife and I are having college-style sex, and it's been a long time since we have set foot on campus. Side effects are fatigue and occasional headache, but overall, the joy of life and the five senses we have are better than ever."

• Msq...
• Taken for 1 to 2 years
• February 2, 2020

For Depression "I've been on and off taking Wellbutrin from 200 mg to 150 mg for two years now. It's good for your depression. The only side effects I experience are dry mouth, mild headaches, and stomach pain. Other than that, I have no problem with Wellbutrin. It keeps me calm. I'm not overthinking about anything, I just feel relaxed and numb."

• TDS...
• Taken for less than 1 month
• November 12, 2019

For Major Depressive Disorder "I had been on Prozac for a year to battle some severe depression and crying daily. It worked well for the first couple of months, but then I noticed it made me feel just 'blah' and negative. I couldn't get emotional either way... angry or sad. I also didn't want to do anything and gained 25 pounds, plus horrible sexual side effects. I got sick of it finally and asked my doctor for something different. He started introducing 150 mg of Wellbutrin for 2 weeks while I reduced the Prozac. The Wellbutrin started working after about a week. My mood was a lot better and I had more emotions. I also feel more motivated to eat right, work out, and improve my appearance. I'm now on one 10 mg Prozac in the morning and 2 separate doses of Wellbutrin (300 mg total). In about a week, I'll drop Prozac and see how it goes. I've only had a slight headache sometimes and a little trouble sleeping, but overall, no side effects with Wellbutrin. Very happy so far."

• Mou...
• Taken for 2 to 5 years
• May 15, 2017

For Depression "I have been on Wellbutrin SR prescribed off-label for major depressive disorder for about 3 years now. Initially, I had the same kind of side effects that are common, such as headache, some anxiety, and difficulty sleeping. The side effects diminished and pretty much went away after about a month, and I take my second dose at midday so that it doesn't impact my sleep. Overall, this medication has made a huge difference in my quality of life and has stopped me from experiencing cripplingly low moods and huge rapid mood swings. It continues to work as well now as it did at the start of treatment. It has also helped me to focus and concentrate on a task in a way that I found hard before. My main concern has been the impact on short-term memory."

• Anonymous
• March 27, 2012

For Depression "I've been taking Wellbutrin for two years for depression. My general mood, concentration, and energy levels are much improved. I have a tendency towards anxiety, but most bad, depressed, or anxious moods last approximately half an hour and then go away. Before I took Wellbutrin, these moods could have lasted days. It slightly decreased my appetite and I've lost ten pounds. Negative side effects have included dry mouth, headaches, and occasional dizziness. Despite these, Wellbutrin has improved my life a lot and I believe that the medicine is more than worth trying."

• Anonymous
• February 20, 2011

For Depression "This is my second time on Wellbutrin XL. I took it once when I was 14-15, with no negative side effects, and I'm now 18. My doctor started me on 150 mg and then bumped me up to 300 mg, and it helped so much. This time when I started, I got headaches for the first 10 days, which were pretty bad sometimes, but it was worth sticking them out (I had headaches during depression anyway). And for a period of 1-2 weeks, I would wake up in the middle of the night for no reason, but I could usually always go back to sleep. I have more energy, and I don't dwell on things as much. Overall, very satisfied."

• Toy...
• January 20, 2010

For Bipolar Disorder "I have been annoyed all the time since I can remember. Always a pessimist. I figured if I expected the worst possible scenario, anything better was a win. It was as if I was at war with the world, everything was a battle. I've been on Wellbutrin for 6 weeks now, 300 mg a day in 2 doses to start. It gave me ridiculously bad headaches (I suffer from migraines already), but my mood, interest, and general sense of well-being were better. My doctor changed me from 2 doses to 3 doses a day (still 300 mg). No more headaches but slight insomnia so far: 3-4 hours a night now, usually getting 6-7 hours of sleep. And I have dry mouth as well. I will deal with the insomnia and cotton mouth. To me, this is worth it."

• Mol...
• Taken for less than 1 month
• December 2, 2022

For Depression "I'm finishing my fourth day on Wellbutrin. Never tried it before. I shared with my GP that I've been having feelings of impending doom-and my sales have decreased significantly with the current economy-worrying a lot. Since self-employment and impending doom are a bad combination, she suggested I try it. I'm 64, but my husband and I enjoy an amazing sex life, and I didn't want to mess that up. And I'm fit, so I didn't want to risk gaining weight. Since starting it (150 mg), I've had a few headaches and a few short periods of nausea. Sleeping is so much fun because the dreams are so vivid. So today, I've had amazing energy-no need for coffee-didn't even think about it. I've been really happy today. Has to be the drug. I can be very difficult and blow my top over little things sometimes, and I always feel so bad afterward. I'm praying this will help me keep things in perspective and not blow things out of proportion. My poor husband has suffered. So far, I would recommend it."

• Anonymous
• Taken for less than 1 month
• November 8, 2022

For Depression "Almost quit taking it at first because of the headaches, insomnia, fatigue, and anger, but kept on taking it, and 2 weeks later, I’m happier, have more energy, I’m actually sleeping better than before I took it, and no longer angry. Really thankful for this medication. (P.S. Was taking 150 XL mg but didn’t notice the drastic change until I got on 300 XL mg.)"

• F21...
• June 14, 2020

For Major Depressive Disorder "This drug Wellbutrin has been life-changing for me. After trying SSRIs and SNRIs that didn’t work, it did the trick. Yes, it sucks at first; the side effects are horrible, but you have to give it time. And on these meds at first, I got the head zaps, anxiety like I had never felt before, heart palpitations, lack of appetite and weight loss, headaches, nausea, severe insomnia - the whole nine yards. But after about 5 months on 300 mg, I turned a corner and feel better than ever. I can focus, I’m not tired but can sleep if I need to, my anxiety largely went away, I’m happy and can orgasm too. All the side effects pretty much subsided, save for the appetite one... I still don’t have to eat if I don’t want to, but I’m not repulsed by the idea of food anymore. So seriously, it isn’t a conventional drug and it’s bad initially, but PLEASE stick with it. Don’t expect it to work overnight... these things take time. I promise you will get results. You got this. Hang in there!"