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Imuran and Weakness: What Users Say

Weakness: mentioned by 7 users (10.9%)

Based on user experiences from 64 Imuran reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 12.5%
weakness 10.9%
vomiting 9.4%
fever 7.8%
headaches 7.8%
allergic reaction 6.3%
chills 6.3%
diarrhea 6.3%
fatigue 6.3%
pain 6.3%

Reviews for Imuran

Commonly mentioned side effects
  • TEP...
  • August 27, 2009

For Myasthenia Gravis "I have been on Imuran for 6 months and find it very helpful for my ocular symptoms and moderately helpful for my generalized myasthenia gravis symptoms (fatigue and weakness). So far, normal hemograms, hepatic function tests, and renal/chem-7 results."

8 / 10
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67 Report
  • MI ...
  • February 18, 2016

For Rheumatoid Arthritis "The first two to three weeks were fine. Then I started experiencing a bad headache, the next two days fever and chills. The next evening, severe chills, weakness, dizziness, raging fever (up to 104.3), and began throwing up. It was the worst I've ever felt in my life (and that includes a hospitalization in ICU when first diagnosed). I was on the verge of calling 911. However, it eventually passed (as the medicine worked its way out of my system) and the fever subsided. My rheumatologist ran a complete series of blood work and she said that I had an allergic reaction. Prior to starting Imuran, I had been tested for liver compatibility and the results showed that I would have no issues, so I proceeded. Proceed with extreme caution."

1 / 10
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45 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • May 2, 2013

For Ulcerative Colitis "Imuran seemed to help for a few months, but after prolonged use, it weakened my immune system too much. I started getting colds about every three weeks, which made me feel run down and tired more so than just having colitis alone, but it did at least calm my symptoms for a while."

5 / 10
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50 Report
  • No...
  • November 9, 2016

For Ulcerative Colitis "Have been on Imuran for 6 years, and it has helped some off and on. In the beginning, I went to the bathroom about 10 to 12 times a day, thus losing a lot of weight, which I didn't expect. Now I go about 3 to 4 times a day, and I do have a flare-up every now and then. Was finally weaned off of prednisone. Have gained some weight back. Overall, the medication has helped, though my immune system has been weakened."

7 / 10
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33 Report
  • But...
  • Taken for less than 1 month
  • April 20, 2017

For Lupus "At the 2-week mark on Imuran 50 mg TID, I developed a high temp, severe muscle aches, chilling, and started coughing up green mucus. I also had severe weakness. Went to MD and put on antibiotics. Called rheumy, and I was taken off the med. CBC and CMP lab was normal."

1 / 10
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29 Report

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  • Anonymous
  • November 23, 2009

For Crohn's Disease, Maintenance "My doctor has put me on Imuran for about three weeks now, and I am starting to feel some side effects, such as weakness, body aches, and breakouts all over my body. So far, not so good with the treatment. I will be calling my doctor for sure."

3 / 10
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26 Report
  • Nic...
  • Taken for 1 to 6 months
  • January 26, 2022

For Lupus "I took it for a month. The first week it made me nauseous, which I just took promethazine to help with, but it didn't take the feeling completely away. I wasn't really eating, and the diarrhea started at 2 weeks. By the 4th week, I felt horrible! Headache, weakness, stomach pain, vomiting, and diarrhea from Sunday to Friday. It was then I knew, although effective for some, and I'd really hoped it would help after seeing so many great reviews, but I requested something else."

1 / 10
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6 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.