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User Reviews for Endep to treat Pain

Endep has an average rating of 6.9 out of 10 from a total of 12 ratings for the treatment of Pain. 67% of those users who reviewed Endep reported a positive effect, while 17% reported a negative effect.

Endep Rating Summary

6.9/10 average rating

12 ratings from 10 user reviews.

Compare all 1432 medications used in the treatment of Pain.


Reviews for Endep

Night Owl · Taken for less than 1 month October 1, 2020

“Endep worked for pain 100% but put me in a mental ward Destroyed my life Get tested to see if you are, allergic to amitripyline first It was very dangerous for me I only had 13 tablets”

1 / 10
Skip · Taken for less than 1 month August 18, 2020

“Endep gave me the worst side effects I've ever had from a medication. I was like a zombie and I was only taking 5mg. Would never take it again. It also made my pain worse”

1 / 10
Afranklin · Taken for less than 1 month December 29, 2019

“I was prescribed Endep for severe Endometriosis. I was very hesitant with it being used as an anti-depressant in some cases, however I must say it works wonderfully. I have been able to go back to work and get on with my life, I do still have outbursts occasionally but it sure beats living on endone in agony! It is a little harder for me to get out of bed in the mornings although I am fine once up. I sleep better and seem happier, of course with the reduced pain. I haven't lost weight drastically or had any fevers or chills as others prescribed. So far very happy. I am 4 weeks in.”

10 / 10

Frequently asked questions

Hayley October 5, 2019

“I am 37 years old I started getting headaches at 13 from what I can remember I went on day to day year after year when I was 26 I was put in hospital with all the drugs Well I was getting headaches monthly bad ones I couldn’t even handle light As the years went on I got them once every 6 months putting me in hospital Then they started coming on every couple of months then once a month all the way down to 3 a week By this stage my face was numb I couldn’t talk or walk could not have any light, losing memory about 3 months ago I went to a brilliant doctor and I couldn’t see so I needed help going there and walking to him He said to me have you heard of ENDEP I have taken my endep every night since for over 3 months now And only had two very very small headaches I’ve been given a second chance at life I’m very grateful I thank my doctor so very much”

10 / 10
Foges · Taken for less than 1 month March 19, 2013

“10mg used to provide a pain free nights sleep. I have a pinched sciatic nerve. After cortizone injection under general anesthetic I experienced cramps that disturbed my sleep. This medicine is now giving me a good nights sleep and I wake refreshed in the morning.”

9 / 10
Zubie · Taken for less than 1 month July 10, 2015

“My dr prescribed this as my pain from arthritis was constantly waking me up every night from day 1 it has enabled me to get a full nights sleep I will keep taking it as nothing else has worked it does not in any way interfere with daily work, a god send”

9 / 10
barsha55 · Taken for 5 to 10 years August 8, 2013

“I am taking Endep 100mgs at night for nerve pain in my lower left leg & the outer side of my right leg. The nerve pain was intolerable and I seriously was suicidal. I have been on Endep as well as Baclofen and Epilim, for 7 years & can now enjoy my life so much more. The down side is loss of libido and dry mouth, but without Endep I could not enjoy my life at all.”

9 / 10

More FAQ

susieoq October 18, 2013

“I have fibromyalgia and take Tramadol 150mg daily. Recently had a flare of trigeminal neuralgia and widespread neuropathic pain and Tramadol was not working for this. Doctor put me back onto Endep, which I had given up previously as the side effects were very strong. Am now on only 5mg at 7pm and find sleep and pain relief much better. Still feel hungover in the morning.”

5 / 10
Hkfygcjb August 10, 2016

“I've been taking 10mg Endep for 2 weeks for bladder pain. I may have a mild case of interstitial cystitis but I haven't been officially diagnosed yet. I have found it has worked really well with the pain. I went from being in pain all the time to only a couple of times and it's been manageable. I have dry mouth and an increased appetite from Endep but the worst side effect is constant drowsiness and a general feeling of being drugged up.”

8 / 10
trishK August 30, 2007

“I have been taking Endep for about 20 yrs. for pain and to help me sleep. I have seen many specialists and gp's over the years and none of them warned me about chronic peridontal disease because of dry mouth. I was on 50mg per day. I had to have three teeth removed. I am now on 25mg. I have many health problems, apparently due to a sero-negative autoimmune disease. I am also having symptoms of headaches, vertigo, dizziness, balance problems, etc. ”

Raysa · Taken for 1 to 2 years April 7, 2018

“I got shingles in December 2016 and have been on and off endep since then. It helped my shingles pain but I get very little sleep. I have to make a choice of not sleeping due to pain, taking endep and have no pain and still not sleep. If there was a natural alternative I'd use that but I've been told that there isn't any. I take Axit for my PTSD and OCD, plus norflex for my grinding teeth at night. I've had insomnia since I was a kid and refuse to take sleeping pills again.”

4 / 10
Chewy 1 July 12, 2013

“Was prescribed Endep 10 for the pain associated with an attack of Shingles. The effect was very good as I had very little pain from the rash or the nerves affected by shingles.”

9 / 10
Megatron14 July 29, 2013

“Started taking 10mg then up to 25 for severe long term migraines/ headaches. Meds work well, am considering lowering dosages and getting off medicines all together to start family now though.”

8 / 10

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.