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Zomig ZMT orally disintegrating tablets

Generic Name: zolmitriptan (ZOLE-mi-TRIP-tan)
Brand Name: Zomig ZMT

Zomig ZMT orally disintegrating tablets are used for:

Treating migraine headaches with or without aura (flashing lights, wavy lines, dark spots) in adults. It is not intended to prevent migraines.

Zomig ZMT orally disintegrating tablets are a serotonin 5-HT1 receptor agonist ("triptan"). It works by narrowing blood vessels in the brain, which helps to relieve migraines.

Do NOT use Zomig ZMT orally disintegrating tablets if:

  • you are allergic to any ingredient in Zomig ZMT orally disintegrating tablets
  • you have certain types of irregular heartbeat (eg, Wolff-Parkinson-White syndrome)
  • you have a history of ischemic heart disease (eg, angina, a heart attack), coronary artery disease (CAD), other moderate to severe heart problems, brain blood vessel disease (eg, a stroke, a transient ischemic attack), or other blood vessel disease (eg, Raynaud syndrome, ischemic bowel disease)
  • you have uncontrolled or severe high blood pressure or moderate to severe liver problems
  • you have certain types of migraines (eg, hemiplegic, basilar, ophthalmoplegic)
  • you have used an ergot derivative (eg, ergotamine, dihydroergotamine) or another "triptan" migraine medicine (eg, eletriptan, rizatriptan) in the last 24 hours
  • you are taking sibutramine
  • you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zomig ZMT orally disintegrating tablets:

Some medical conditions may interact with Zomig ZMT orally disintegrating tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of liver or kidney problems, seizures (eg, epilepsy), growths in the brain, heart problems (eg, irregular heartbeat), other types of headaches (eg, cluster headaches), or phenylketonuria (PKU)
  • if you have shortness of breath, chest pain, or a history of high blood pressure, high cholesterol, diabetes, or smoking
  • if you are a woman who is past menopause
  • if you are a male who is older than 40 years old
  • if you are very overweight
  • if a family member has had heart disease or a stroke

Some MEDICINES MAY INTERACT with Zomig ZMT orally disintegrating tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), serotonin-norepinephrine reuptake inhibitors (SNRIs) (eg, duloxetine), sibutramine, or tricyclic antidepressants (eg, amitriptyline) because the risk of a serious side effect called serotonin syndrome may be increased. Symptoms of serotonin syndrome may include mental or mood changes, hallucinations, fast heartbeat, fever, loss of coordination, muscle spasms, increased sweating, nausea, vomiting, or diarrhea
  • Cimetidine, MAOIs (eg, phenelzine), or quinolone antibiotics (eg, ciprofloxacin) because they may increase the risk of Zomig ZMT orally disintegrating tablets's side effects
  • Ergot derivatives (eg, ergotamine, dihydroergotamine ) or another "triptan" migraine medicine (eg, eletriptan, rizatriptan) because the risk of their side effects may be increased by Zomig ZMT orally disintegrating tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Zomig ZMT orally disintegrating tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zomig ZMT orally disintegrating tablets:

Use Zomig ZMT orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Zomig ZMT orally disintegrating tablets. Talk to your pharmacist if you have questions about this information.
  • Take Zomig ZMT orally disintegrating tablets by mouth with or without food.
  • It is best to use Zomig ZMT orally disintegrating tablets as soon as you notice the headache symptoms of a migraine attack.
  • Open tablet blister pack with dry hands and place the tablet on the tongue. Do not try to split or break the tablets.
  • Take the tablet immediately after removing it from its blister. Do not store the removed tablet for future use. Throw away any unused tablets or portions that have been removed from the blister pack.
  • The tablet will dissolve rapidly on the tongue and can be swallowed with saliva. It is not necessary to take Zomig ZMT orally disintegrating tablets with liquid.
  • If your migraine symptoms go away and then come back, you may take a second dose as directed by your doctor. Wait at least 2 hours between doses.
  • If your symptoms do not get better after the first dose, do not take a second dose for the same attack. Contact your doctor.
  • Do NOT take more than the amount prescribed by your doctor in a 24-hour period or treat more than 3 headaches within 30 days without checking with your doctor.
  • If your medicine has expired, throw it away.
  • If you miss a dose of Zomig ZMT orally disintegrating tablets and you still have a headache, follow your doctor's dosing instructions. Contact your doctor if you are unsure of what to do if you miss a dose. Do NOT use Zomig ZMT orally disintegrating tablets more often than prescribed. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Zomig ZMT orally disintegrating tablets.

Important safety information:

  • Zomig ZMT orally disintegrating tablets may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Zomig ZMT orally disintegrating tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Overuse of Zomig ZMT orally disintegrating tablets can cause your headache to become worse. Do NOT take more than the recommended dose or use more often than prescribed without checking with your doctor.
  • Rarely, serious heart problems (eg, heart attack, irregular heartbeat) have been reported within a few hours of using Zomig ZMT orally disintegrating tablets. Contact your doctor at once if fast or irregular heartbeat; chest, jaw, or neck pain or numbness; sudden, severe nausea or vomiting; sudden, unusual sweating or weakness; shortness of breath; fainting; or vision changes occur. Discuss any questions or concerns with your doctor.
  • Serotonin syndrome is a possibly fatal syndrome that can be caused by Zomig ZMT orally disintegrating tablets. Your risk may be greater if you take Zomig ZMT orally disintegrating tablets with certain other medicines (eg, SSRIs, SNRIs). Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms.
  • Zomig ZMT orally disintegrating tablets should not be used to prevent or reduce the number of migraine headaches you have. If you have a headache that is different than your usual migraine headaches, check with your doctor before using Zomig ZMT orally disintegrating tablets.
  • Zomig ZMT orally disintegrating tablets contains phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
  • Lab tests, including heart function and blood pressure, may be performed while you use Zomig ZMT orally disintegrating tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Zomig ZMT orally disintegrating tablets with caution in the ELDERLY; they may be more sensitive to its effects.
  • Zomig ZMT orally disintegrating tablets should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zomig ZMT orally disintegrating tablets while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking Zomig ZMT orally disintegrating tablets.

Possible side effects of Zomig ZMT orally disintegrating tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning, numbness, or tingling of the skin; dizziness; drowsiness; dry mouth; feeling of heaviness or pressure in areas of the body other than the jaw, neck, throat, or chest; nausea or stomach upset; warm or cold sensation; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); bloody diarrhea; confusion; fainting; fast or irregular heartbeat; mental or mood changes; one-sided weakness; pain, tightness, heaviness, or pressure in the jaw, neck, throat, or chest; severe or persistent headache or dizziness; shortness of breath; slurred speech; sudden, severe nausea or vomiting; sudden, unusual sweating or weakness; sudden or severe stomach pain; very cold or blue fingers or toes; vision loss or other vision changes; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include unusual drowsiness.

Proper storage of Zomig ZMT orally disintegrating tablets:

Store Zomig ZMT orally disintegrating tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Zomig ZMT orally disintegrating tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about Zomig ZMT orally disintegrating tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Zomig ZMT orally disintegrating tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Zomig ZMT orally disintegrating tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Zomig ZMT orally disintegrating tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Zomig ZMT orally disintegrating tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Zomig ZMT orally disintegrating tablets.

Review Date: August 8, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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