Generic Name: Enzalutamide (en za LOO ta mide)
Brand Name: Xtandi
Uses of Xtandi:
- It is used to treat prostate cancer.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Xtandi?
- If you have an allergy to enzalutamide or any other part of Xtandi (enzalutamide).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are taking any of these drugs: Alfentanil, cyclosporine, dihydroergotamine, ergotamine, fentanyl, phenytoin, pimozide, quinidine, sirolimus, or tacrolimus.
- If you are a woman. This medicine is not approved for use in women. If you are a woman using this medicine, talk with your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding.
This is not a list of all drugs or health problems that interact with Xtandi.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Xtandi?
- Tell all of your health care providers that you take Xtandi. This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Some people have had seizures while taking this medicine. The chance of seizures may be raised if you have certain brain blood vessel problems, take other drugs that may raise the chance of seizures, or if you have ever had seizures, brain injury, stroke, or brain cancer. Avoid tasks or actions where passing out may cause harm to you or others. Talk with your doctor.
- The chance of falling is raised with Xtandi. Falls may lead to very bad problems like head injury and broken bones. The chance of falling is higher in older people. Talk with the doctor.
- High blood pressure has happened with drugs like this one. Have your blood pressure checked as you have been told by your doctor.
- This medicine interacts with many other drugs. The chance of this medicine's side effects may be raised or how well Xtandi works may be lowered. Check with your doctor and pharmacist to make sure that it is safe for you to take this medicine with all of your other drugs (prescription or OTC, natural products, vitamins).
- If you are taking warfarin, talk with your doctor. You may need to have your blood work checked more closely while you are taking it with Xtandi.
- This medicine may affect being able to father a child. Talk with the doctor.
- This medicine may cause harm to an unborn baby. If you have sex, protect your partner from pregnancy. Use a condom and another form of birth control that you can trust while taking this medicine and for 3 months after your last dose.
- If you are a man and your sex partner gets pregnant while you take Xtandi or within 3 months after your last dose, call your doctor right away.
- If you are having sex and your partner is pregnant, use a condom while taking this medicine and for 3 months after your last dose.
How is this medicine (Xtandi) best taken?
Use Xtandi (enzalutamide) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take this medicine at the same time of day.
- Take with or without food.
- Swallow whole. Do not chew, break, open, or melt.
- To gain the most benefit, do not miss doses.
- Keep taking Xtandi as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If you do not think about the missed dose until the next day, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Shortness of breath.
- A burning, numbness, or tingling feeling that is not normal.
- Blood in the urine.
- Swelling in the arms or legs.
- Bone pain.
- Memory problems or loss.
- A very bad and sometimes deadly brain problem called posterior reversible encephalopathy syndrome (PRES) has happened with this medicine. Call your doctor right away if you have signs like feeling confused, lowered alertness, change in eyesight, loss of eyesight, seizures, or very bad headache.
- This medicine may raise the chance of infections. Call your doctor right away if you have signs of infection like fever, chills, sore throat, redness or swelling of the skin.
What are some other side effects of Xtandi?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling tired or weak.
- Back pain.
- Not hungry.
- Hard stools (constipation).
- Muscle pain or weakness.
- Joint pain.
- Loose stools (diarrhea).
- Hot flashes.
- Signs of a common cold.
- Weight loss.
- Not able to sleep.
- Change in taste.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Xtandi?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Xtandi, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Xtandi. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using Xtandi.
Review Date: December 6, 2017
More about Xtandi (enzalutamide)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 4 Reviews – Add your own review/rating
- Drug class: antiandrogens