Skip to Content


Generic Name: Vismodegib (vis moe DEG ib)
Brand Name: Erivedge

Medically reviewed by Last updated on May 31, 2020.


  • This medicine may cause harm to the unborn baby or loss of the unborn baby if you take it while you are pregnant.
  • If you are a woman who can get pregnant, you will need to have a pregnancy test within 7 days before you start taking vismodegib. You will need to use birth control that you can trust to prevent pregnancy while taking vismodegib and for 24 months after your last dose. Talk with your doctor about what kind of birth control is best for you.
  • If you are a woman and you miss a period, have unprotected sex, or think that your birth control has not worked, call your doctor right away.
  • If you get pregnant while taking vismodegib or within 24 months after your last dose, call your doctor right away.
  • If you are a man and have sex with a pregnant female or a female who could get pregnant, you must use a condom during treatment and for 3 months after your last dose. Use a condom even if you have had a vasectomy. Talk with your doctor right away if your partner is pregnant or if she gets pregnant or thinks she is pregnant during this time.

Uses of Vismodegib:

  • It is used to treat skin cancer.

What do I need to tell my doctor BEFORE I take Vismodegib?

  • If you have an allergy to vismodegib or any other part of vismodegib.
  • If you are allergic to vismodegib; any part of vismodegib; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you are breast-feeding. Do not breast-feed while you take vismodegib or within 24 months after you stop taking it.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take vismodegib with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Vismodegib?

  • Tell all of your health care providers that you take vismodegib. This includes your doctors, nurses, pharmacists, and dentists.
  • Do not donate blood or blood products while taking vismodegib and for 24 months after your last dose.
  • This medicine is found in semen. Do not donate semen while you take vismodegib and for 3 months after your last dose.
  • This medicine may cause menstrual periods to stop in females who can get pregnant. This may affect being able to have children. It is not known if this will go back to normal. Talk with the doctor.
  • This medicine is not approved for use in children. Bone growth problems have happened in children who have taken vismodegib. These problems may keep going after vismodegib is stopped. Talk with the doctor.

How is this medicine (Vismodegib) best taken?

Use vismodegib as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food.
  • Swallow whole. Do not chew, open, or crush.

What do I do if I miss a dose?

  • Skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

What are some other side effects of Vismodegib?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Vismodegib?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep lid tightly closed.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time vismodegib is refilled. If you have any questions about vismodegib, please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.