Generic Name: amlodipine/olmesartan/hydrochlorothiazide (am-LOE-di-peen/OL-me-SAR-tan/HYE-droe-KLOR-oh-THYE-a-zide)
Brand Name: Tribenzor
Tribenzor may cause birth defects or fetal and newborn death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. If you are planning to become pregnant, talk with your doctor about other treatment options.
Tribenzor is used for:
Treating high blood pressure. It may also be used for other conditions as determined by your doctor.
Tribenzor is a calcium channel blocker, angiotensin II receptor blocker, and thiazide diuretic combination. It works by relaxing the blood vessels and helping the kidneys remove fluid from the body.
Do NOT use Tribenzor if:
- you are allergic to any ingredient in Tribenzor or to any other sulfonamide medicine (eg, sulfamethoxazole)
- you are pregnant
- you have severe kidney problems or are unable to urinate
- you are taking a medicine that contains aliskiren and you also have diabetes or kidney problems. Check with your doctor or pharmacist if you are not sure if a medicine you take contains aliskiren
- you are taking dofetilide or ketanserin
Contact your doctor or health care provider right away if any of these apply to you.
Before using Tribenzor:
Some medical conditions may interact with Tribenzor. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are able to become pregnant
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you are vomiting or have diarrhea
- if you are dehydrated, have low blood volume or fluid retention (swelling), are on a low-salt (sodium) diet, or have high or low blood electrolyte levels (eg, sodium, magnesium, potassium, calcium)
- if you have gallbladder, liver, or kidney problems; asthma; gout or high blood levels of uric acid; lupus; parathyroid gland problems; low blood pressure; blood vessel problems; heart problems (eg, heart failure, angina, narrowing of heart blood vessels); or high blood cholesterol or lipid levels
- if you have a history of a stroke or heart attack
- if you are on dialysis, have recently had surgery (eg, a certain type of nerve surgery called sympathectomy), or will be having surgery
- if you are taking another medicine for blood pressure or heart problems, or if you have never taken a blood pressure medicine before
Some MEDICINES MAY INTERACT with Tribenzor. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Digoxin, dofetilide, or ketanserin because the risk of irregular heartbeat may be increased
- Potassium-sparing diuretics (eg, triamterene) or potassium supplements because the risk of high blood potassium levels may be increased
- Aliskiren or angiotensin-converting enzyme (ACE) inhibitors (eg, ramipril) because the risk of certain side effects (eg, kidney problems, high blood potassium levels, low blood pressure) may be increased
- Adrenocorticotropic hormone (ACTH), azole antifungals (eg, itraconazole), barbiturates (eg, phenobarbital), conivaptan, corticosteroids (eg, prednisone), diuretics (eg, furosemide), macrolide antibiotics (eg, clarithromycin), narcotic pain relievers (eg, morphine), protease inhibitors (eg, ritonavir, telaprevir), sildenafil, or other medicines for high blood pressure because they may increase the risk of Tribenzor's side effects
- Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, celecoxib, ibuprofen) because they may decrease Tribenzor's effectiveness and the risk of serious kidney problems may be increased
- Diazoxide, lithium, simvastatin, or tacrolimus because the risk of their side effects and toxic effects may be increased by Tribenzor
- Insulin or other diabetes medicines (eg, glipizide, metformin) because their effectiveness may be decreased by Tribenzor
This may not be a complete list of all interactions that may occur. Ask your health care provider if Tribenzor may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Tribenzor:
Use Tribenzor as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Tribenzor. Talk to your pharmacist if you have questions about this information.
- Take Tribenzor by mouth with or without food.
- Tribenzor may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
- Take Tribenzor on a regular schedule to get the most benefit from it. Taking Tribenzor at the same time each day will help you remember to take it.
- If you take cholestyramine or colestipol, ask your doctor or pharmacist how to take it with Tribenzor.
- Continue to take Tribenzor even if you feel well. Do not miss any doses.
- If you miss a dose of Tribenzor, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Tribenzor.
Important safety information:
- Tribenzor may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Tribenzor with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Tribenzor may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Do not drink alcohol while you are taking Tribenzor.
- It may take up to 2 weeks for Tribenzor to reach its full effect. Do not exceed the recommended dose or stop taking Tribenzor without checking with your doctor.
- Your doctor may also prescribe a potassium supplement for you. If so, take the potassium supplement exactly as prescribed. Do not start taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor.
- Check with your doctor before you use a salt substitute or a product that has potassium in it.
- If vomiting, diarrhea, or excessive sweating occurs, you will need to take care not to become dehydrated. This could increase your risk of low blood pressure. Contact your doctor for instructions.
- Your risk of low blood pressure may be increased if you do not drink enough fluids while you are taking Tribenzor. Check with your doctor if you have questions about the proper amount of fluids you should be drinking.
- Tribenzor may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Tribenzor. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Tribenzor contains a sulfonamide called hydrochlorothiazide, which can cause certain eye problems (myopia, angle-closure glaucoma). Your risk may be increased if you are allergic to sulfonamide medicines (eg, sulfamethoxazole) or to penicillin antibiotics (eg, amoxicillin). Untreated angle-closure glaucoma can lead to permanent vision loss. If these eye problems occur, symptoms usually occur within hours to weeks of starting Tribenzor. Contact your doctor immediately if you experience symptoms such as vision changes (eg, decreased vision clearness) or eye pain.
- A certain bowel problem has happened in some patients taking Tribenzor. This has happened within months to years after Tribenzor was started. Contact your doctor right away if you experience severe or persistent diarrhea, or sudden or unexplained weight loss.
- Tribenzor may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
- Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Tell your doctor or dentist that you take Tribenzor before you receive any medical or dental care, emergency care, or surgery.
- Talk with your doctor or pharmacist about all of your blood pressure medicines and how to use them. Do not start, stop, or change the dose of any blood pressure medicine unless your doctor tells you to.
- Tribenzor may interfere with certain lab tests, including parathyroid function tests. Be sure your doctor and lab personnel know you are taking Tribenzor.
- Lab tests, including blood pressure, kidney function, and blood electrolyte levels, may be performed while you take Tribenzor. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Tribenzor with caution in the ELDERLY; they may be more sensitive to its effects.
- Tribenzor should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Tribenzor may cause birth defects or fetal or newborn death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. Tribenzor is found breast milk. Do not breast-feed while taking Tribenzor.
Possible side effects of Tribenzor:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Dizziness; headache; light-headedness; muscle spasms; nausea; sore throat; stuffy or runny nose; tiredness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); burning, numbness, or tingling sensation; burning or painful urination; change in the amount of urine produced; confusion; dark urine; eye pain; fainting; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; joint pain, swelling, warmth, or redness (especially of the big toe); loss of appetite; mental or mood changes; muscle pain, weakness, or cramps; new or worsening chest pain (eg, longer, more often, more severe); pale stools; red, swollen, blistered, or peeling skin; seizures; severe or persistent dizziness, drowsiness, or light-headedness; severe or persistent dry mouth; severe or persistent nausea, vomiting, or stomach pain; shortness of breath; stiff muscles, tremors, or muscle movements that are not normal; sudden, unexplained weight gain; swelling of the feet, ankles, or hands; symptoms of a heart attack (eg, chest, jaw, or left arm pain; numbness of an arm or leg; sudden headache or vomiting; sudden vision changes); tender, bleeding, or swollen gums; unusual bruising or bleeding; unusual restlessness or sluggishness; unusual thirst, tiredness, or weakness; vision changes (eg, blurred vision, decreased vision clearness, double vision); yellowing of the eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Tribenzor:
Store Tribenzor between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tribenzor out of the reach of children and away from pets.
- If you have any questions about Tribenzor, please talk with your doctor, pharmacist, or other health care provider.
- Tribenzor is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Tribenzor or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Tribenzor. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Tribenzor. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Tribenzor.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Tribenzor (amlodipine / hydrochlorothiazide / olmesartan)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 14 Reviews – Add your own review/rating
- Generic Availability