Generic Name: tranexamic acid (TRAN-ex-AM-ik AS-id)
Brand Name: Lysteda
Tranexamic acid is used for:
Treating heavy menstrual bleeding.
Tranexamic acid is an antifibrinolytic. It works by preventing blood clots from breaking down too quickly. This helps to reduce excessive bleeding.
Do NOT use tranexamic acid if:
- you are allergic to any ingredient in tranexamic acid
- you have blood clots (eg, in the leg, lung, eye, brain), a history of blood clots, or conditions that may increase your risk of blood clots (eg, certain heart valve problems, certain types of irregular heartbeat, certain blood clotting problems)
- you have bleeding in the brain, blood in the urine, or bleeding related to kidney problems
- you have a disturbance of color vision
- you have irregular menstrual bleeding of unknown cause
- you are using birth control that contains estrogen and a progestin (eg, birth control pill, patch, or vaginal ring)
- you are using medicine to help your blood clot (eg, factor IX complex concentrates or anti-inhibitor coagulant concentrates)
Contact your doctor or health care provider right away if any of these apply to you.
Before using tranexamic acid:
Some medical conditions may interact with tranexamic acid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of kidney problems, bleeding or blood clotting problems, a certain blood problem called disseminated intravascular coagulation (DIC), eye or vision problems, or bleeding in the brain
- if the time between the start of your periods is less than 21 days or more than 35 days
Some MEDICINES MAY INTERACT with tranexamic acid. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Hormonal birth control (eg, birth control pills), medicines to help your blood clot (eg, anti-inhibitor coagulant concentrates, factor IX complex concentrates), or tretinoin (all-trans retinoic acid) because the risk of blood clots may be increased
- Anticoagulants (eg, warfarin) because they may decrease tranexamic acid's effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if tranexamic acid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use tranexamic acid:
Use tranexamic acid as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with tranexamic acid. Talk to your pharmacist if you have questions about this information.
- Take tranexamic acid by mouth with or without food.
- Swallow tranexamic acid whole with plenty of liquids. Do not break, crush, or chew before swallowing.
- Only take tranexamic acid after your period has started. Do not take more than 3 doses (6 tablets) within 24 hours. Do not take tranexamic acid for more than 5 days within any menstrual cycle. Discuss any questions with your doctor.
- If you miss a dose of tranexamic acid, take it as soon as you remember, then take your next dose at least 6 hours later. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use tranexamic acid.
Important safety information:
- Tranexamic acid may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use tranexamic acid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- If your symptoms do not get better after 2 menstrual cycles, if they get worse, or if tranexamic acid seems to stop working, check with your doctor.
- If you notice an unusual change in your bleeding pattern, check with your doctor.
- The risk of a stroke, a heart attack, or other blood clots may be increased when tranexamic acid is used with hormonal birth control (eg, birth control pills). The risk may be greater if you are very overweight or if you smoke cigarettes, especially if you are older than 35 years old. Discuss any questions or concerns with your doctor.
- Tell your doctor or dentist that you take tranexamic acid before you receive any medical or dental care, emergency care, or surgery.
- Lab tests, including eye exams, may be performed while you use tranexamic acid. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Tranexamic acid should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
- Use tranexamic acid with caution in the ELDERLY; they may be more sensitive to its effects.
- Tranexamic acid is not indicated in women who have been through menopause or in children who have not had their first menstrual period. Discuss any questions or concerns with your doctor.
- PREGNANCY and BREAST-FEEDING: Tranexamic acid is not approved for use in pregnant women. If you become pregnant while taking tranexamic acid, contact your doctor. Tranexamic acid is found in breast milk. If you are or will be breast-feeding while you take tranexamic acid, check with your doctor or pharmacist. Discuss any possible risks to your baby.
Possible side effects of tranexamic acid:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Back pain; headache; joint pain; muscle pain, spasms, or cramps; nasal or sinus congestion; stomach pain; tiredness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest or throat; swelling of the mouth, face, lips, or tongue; flushing of the face); calf or leg pain, swelling, or tenderness; chest pain; confusion; coughing up blood; decreased urination or difficulty urinating; eye problems; fainting; numbness of an arm or leg; one-sided weakness; seizures; severe or persistent dizziness or light-headedness; shortness of breath; slurred speech; sudden, severe headache or vomiting; unusual tiredness or weakness; vision changes or problems (eg, disturbance of color vision, sharpness, or field of vision).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of tranexamic acid:
Store tranexamic acid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep tranexamic acid out of the reach of children and away from pets.
- If you have any questions about tranexamic acid, please talk with your doctor, pharmacist, or other health care provider.
- Tranexamic acid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take tranexamic acid or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about tranexamic acid. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to tranexamic acid. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using tranexamic acid.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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