Generic Name: Pertuzumab (per TU zoo mab)
Brand Name: Perjeta
Medically reviewed by Drugs.com. Last updated on Oct 11, 2020.
- This medicine may cause heart failure. You will need to have your heart function checked while taking Perjeta (pertuzumab). Call your doctor right away if you have signs of heart problems like a cough or shortness of breath that is new or worse, swelling of the ankles or legs, a heartbeat that does not feel normal, weight gain of more than 5 pounds in 24 hours, dizziness, or passing out.
- This medicine with trastuzumab may cause harm to the unborn baby or loss of the unborn baby if used during pregnancy or within 7 months after the last dose.
- Use birth control that you can trust to prevent pregnancy while taking Perjeta (pertuzumab) and for at least 7 months after stopping Perjeta (pertuzumab).
- If you get pregnant while taking Perjeta (pertuzumab) or within 7 months after your last dose, call your doctor right away.
Uses of Perjeta:
- It is used to treat breast cancer.
What do I need to tell my doctor BEFORE I take Perjeta?
- If you are allergic to Perjeta (pertuzumab); any part of Perjeta (pertuzumab); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are breast-feeding. Do not breast-feed while you take Perjeta (pertuzumab). You will also need to avoid breast-feeding after you stop Perjeta (pertuzumab) until there is no more of Perjeta (pertuzumab) in your body. Talk with your doctor to see how long you need to avoid breast-feeding after you stop this drug.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Perjeta (pertuzumab) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Perjeta?
- Tell all of your health care providers that you take Perjeta (pertuzumab). This includes your doctors, nurses, pharmacists, and dentists.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- If you have upset stomach, throwing up, diarrhea, or are not hungry, talk with your doctor. There may be ways to lower these side effects.
- Very bad and sometimes deadly side effects have happened during the infusion. Tell your doctor if you have any bad effects during the infusion.
- Very bad and sometimes deadly allergic reactions have rarely happened. Talk with your doctor.
- You will need to have heart function tests while taking Perjeta (pertuzumab). Talk with the doctor.
- If you are 65 or older, use Perjeta (pertuzumab) with care. You could have more side effects.
- If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting Perjeta (pertuzumab). Talk with your doctor.
How is this medicine (Perjeta) best taken?
Use Perjeta (pertuzumab) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Chest pain or pressure or a fast heartbeat.
- Any unexplained bruising or bleeding.
- A burning, numbness, or tingling feeling that is not normal.
- This medicine may cause a bad and sometimes deadly health problem called tumor lysis syndrome (TLS). Call your doctor right away if you have a fast heartbeat or a heartbeat that does not feel normal; any passing out; trouble passing urine; muscle weakness or cramps; upset stomach, throwing up, loose stools or not able to eat; or feel sluggish.
- A very bad and sometimes deadly health problem called cytokine release syndrome (CRS) has happened in people getting Perjeta (pertuzumab). Call your doctor right away if you have chills, dizziness, feeling tired or weak, fever, headache, passing out, rash, swelling of the face, trouble breathing, upset stomach or throwing up, or wheezing.
What are some other side effects of Perjeta?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling dizzy, tired, or weak.
- Upset stomach or throwing up.
- Stomach pain or diarrhea.
- Mouth irritation or mouth sores.
- Not hungry.
- Change in taste.
- Dry skin.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Perjeta?
- If you need to store Perjeta (pertuzumab) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Perjeta (pertuzumab), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Frequently Asked Questions
- How long can you stay on Herceptin and Perjeta?
- How long do Perjeta infusions last?
- Is Perjeta a chemotherapy drug?
- How much does Perjeta cost?
- What common side effects occur with Perjeta?
More about Perjeta (pertuzumab)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: HER2 inhibitors
- FDA Approval History