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Penicillin G Procaine

Generic Name: Penicillin G Procaine (pen i SIL in jee PROE kane)

Medically reviewed on July 4, 2018

Uses of Penicillin G Procaine:

  • It is used to treat bacterial infections.

What do I need to tell my doctor BEFORE I take Penicillin G Procaine?

  • If you have an allergy to penicillin, procaine, or any other part of penicillin G procaine.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are taking tetracycline.

This is not a list of all drugs or health problems that interact with penicillin G procaine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take penicillin G procaine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Penicillin G Procaine?

  • Tell all of your health care providers that you take penicillin G procaine. This includes your doctors, nurses, pharmacists, and dentists.
  • Have your blood work checked if you are on penicillin G procaine for a long time. Talk with your doctor.
  • Very bad and sometimes deadly allergic side effects have rarely happened. Talk with your doctor.
  • Do not use longer than you have been told. A second infection may happen.
  • If you have asthma, talk with your doctor. You may be more sensitive to penicillin G procaine.
  • Use with care in newborns. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using penicillin G procaine while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Penicillin G Procaine) best taken?

Use penicillin G procaine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as a shot into a muscle.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Any unexplained bruising or bleeding.
  • Fever or chills.
  • Swelling.
  • Joint pain.
  • Very bad dizziness or passing out.
  • Anxiety.
  • Feeling confused.
  • Feeling agitated.
  • Low mood (depression).
  • Feeling very tired or weak.
  • Seizures.
  • Hallucinations (seeing or hearing things that are not there).
  • Change in how you act.
  • Nerve damage can happen if penicillin G procaine is given into or near a nerve. This could be long-lasting. Call your doctor right away if you have any numbness, tingling, or weakness.
  • It is common to have diarrhea when taking penicillin G procaine. Rarely, a very bad form of diarrhea called Clostridium difficile (C diff)–associated diarrhea (CDAD) may occur. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen while you are taking penicillin G procaine or within a few months after you stop taking it. Call your doctor right away if you have stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat loose stools without first checking with your doctor.

What are some other side effects of Penicillin G Procaine?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Loose stools (diarrhea).

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Penicillin G Procaine?

  • If you need to store penicillin G procaine at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about penicillin G procaine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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