Generic Name: doxycycline (DOX-i-SYE-kleen)
Brand Name: Oracea
Oracea is used for:
Treating inflammatory lesions caused by rosacea.
Oracea is a tetracycline. Tetracyclines are often used to treat infections; however, Oracea will not treat infection. It works by reducing skin inflammation caused by rosacea.
Do NOT use Oracea if:
- you are allergic to any ingredient in Oracea or to another tetracycline (eg, minocycline)
- you are taking acitretin, isotretinoin, methoxyflurane, or a penicillin antibiotic (eg, amoxicillin)
- you have recently received or will be receiving a live oral typhoid vaccine
Contact your doctor or health care provider right away if any of these apply to you.
Before using Oracea:
Some medical conditions may interact with Oracea. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have diarrhea, a history of kidney or liver problems, the blood disease porphyria, lupus, or recurring fungal infections in the mouth or vagina
- if you have a history of stomach surgery (eg, gastric bypass surgery for weight loss) or other conditions that may cause a low amount of acid in your stomach
- if you use tanning booths, sunlamps, or spend a lot of time in the sun
Some MEDICINES MAY INTERACT with Oracea. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Acitretin, isotretinoin, or methoxyflurane because the risk of increased pressure in the brain and fatal kidney toxicity may be increased
- Anticoagulants (eg, warfarin), digoxin, or methotrexate because their risk of side effects and toxic effects may be increased by Oracea
- Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), iron, proton pump inhibitors (eg, omeprazole), or urinary alkalinizers (eg, sodium bicarbonate) because they may decrease Oracea's effectiveness
- Live oral typhoid vaccine, hormonal birth control (eg, birth control pills), or penicillins (eg, amoxicillin) because their effectiveness may be decreased by Oracea
This may not be a complete list of all interactions that may occur. Ask your health care provider if Oracea may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Oracea:
Use Oracea as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Oracea. Talk to your pharmacist if you have questions about this information.
- Take Oracea by mouth on an empty stomach at least 1 hour before or 2 hours after eating.
- Swallow Oracea whole with a full glass of water (8 oz/240 mL) to help reduce the risk of throat or esophagus irritation. Do not break, crush, or chew Oracea before swallowing. Do not lie down for 30 minutes after taking Oracea.
- Do not take bismuth-containing products, iron, multivitamins with minerals or iron, urinary alkalinizers (eg, sodium bicarbonate), or an antacid that has aluminum, calcium, or magnesium in it within 2 hours before or 2 hours after you take Oracea.
- If you miss a dose of Oracea, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Oracea.
Important safety information:
- Oracea is only used to treat skin problems caused by rosacea. Do not use Oracea to treat or prevent infections.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Do not receive a live vaccine (eg, measles, mumps) while you are taking Oracea. Talk with your doctor before you receive any vaccine.
- Oracea may discolor the skin, scars, teeth, or gums. Check with your doctor if you have questions about these effects.
- Oracea may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Oracea. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Mild diarrhea is common with this type of medicine. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use Oracea or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
- Hormonal birth control (eg, birth control pills) may not work as well while you are using Oracea. To prevent pregnancy, use an extra form of birth control (eg, condoms).
- Oracea should not be used by men or women who are trying to conceive a child. If you are trying to conceive a child, check with your doctor about the risks and benefits of using Oracea.
- Tell your doctor or dentist that you take Oracea before you receive any medical or dental care, emergency care, or surgery.
- Oracea may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Oracea.
- Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use Oracea. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Oracea should not be used in CHILDREN younger than 8 years old; permanent yellow-gray-brown tooth discoloration may occur.
- PREGNANCY and BREAST-FEEDING: Oracea has been shown to cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Oracea while you are pregnant. Oracea is found in breast milk. Do not breast-feed while taking Oracea.
Possible side effects of Oracea:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; nose or throat irritation; sensitivity to sunlight.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; chest pain; dark urine; decreased urination; fever, chills, or sore throat; moderate to severe sunburn; red, swollen, blistered, or peeling skin; severe diarrhea; severe or persistent headache; stomach pain or cramps; throat irritation; trouble swallowing; unusual bruising or bleeding; unusual joint pain; unusual tiredness; vaginal irritation or discharge; vision changes; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Oracea:
Store Oracea at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Oracea out of the reach of children and away from pets.
- If you have any questions about Oracea, please talk with your doctor, pharmacist, or other health care provider.
- Oracea is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Oracea or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Oracea. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Oracea. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Oracea.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.