Generic Name: Ondansetron Injection (on DAN se tron)
Brand Name: Zofran
Medically reviewed by Drugs.com. Last updated on Feb 11, 2019.
Uses of Ondansetron Injection:
- It is used to treat or prevent upset stomach and throwing up.
What do I need to tell my doctor BEFORE I take Ondansetron Injection?
- If you have an allergy to ondansetron or any other part of ondansetron injection.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have a long QT on ECG.
- If you are taking apomorphine.
This is not a list of all drugs or health problems that interact with ondansetron injection.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take ondansetron injection with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Ondansetron Injection?
- Tell all of your health care providers that you take ondansetron injection. This includes your doctors, nurses, pharmacists, and dentists.
- You may need to have an ECG checked before starting ondansetron injection and while taking it. Talk with your doctor.
- If you are 65 or older, use ondansetron injection with care. You could have more side effects.
- The prefilled syringes are not for use in children who weigh less than 88 lb (40 kg). Talk with the doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using ondansetron injection while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Ondansetron Injection) best taken?
Use ondansetron injection as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a vein.
- Your doctor may teach you how to give the shot.
- Follow how to use carefully.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- If you take ondansetron injection on a regular basis, take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Many times ondansetron injection is taken on an as needed basis. Do not take more often than told by the doctor.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Chest pain or pressure.
- Slow heartbeat.
- Numbness and tingling.
- Belly pain.
- Trouble passing urine.
- Trouble controlling body movements.
- Change in eyesight.
- Feeling very sleepy.
- Fever or chills.
- A type of abnormal heartbeat (prolonged QT interval) can happen with ondansetron injection. Call your doctor right away if you have a fast heartbeat, a heartbeat that does not feel normal, or if you pass out.
- A very bad and sometimes deadly health problem called serotonin syndrome may happen. The risk may be greater if you take ondansetron injection with drugs for depression, migraines, or certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; very bad diarrhea, upset stomach, or throwing up; or very bad headache.
What are some other side effects of Ondansetron Injection?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling tired or weak.
- Feeling sleepy.
- Irritation where the shot is given.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Ondansetron Injection?
- Most of the time, ondansetron injection will be given in a hospital or doctor's office. If stored at home, follow how to store as you were told by the doctor.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about ondansetron injection, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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