Generic Name: Alosetron (a LOE se tron)
Brand Name: Lotronex
Medically reviewed on May 2, 2018
- Very bad GI (gastrointestinal) side effects have rarely happened in people taking Lotronex (alosetron). Sometimes, these have led to a hospital stay and, rarely, blood transfusions, surgery, and death. Call your doctor right away if you get constipation, new or worse stomach pain, rectal bleeding, or blood in your stools.
- This medicine is only approved for some women who have tried other drugs and the drugs have not worked. Talk with your doctor.
Uses of Lotronex:
- It is used to treat irritable bowel syndrome.
What do I need to tell my doctor BEFORE I take Lotronex?
- If you have an allergy to alosetron or any other part of Lotronex (alosetron).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have hard stools (constipation).
- If you have ever had any of these health problems: Blood clots or blood-clotting problems, blood flow problems in the bowel, bowel block, Crohn's disease, diverticulitis, hole in the GI (gastrointestinal) tract, ischemic or ulcerative colitis, a large colon, liver problems, long-term or very hard stools (constipation), or narrowing or growths in the bowel.
- If you are taking fluvoxamine.
- If the patient is a child. Do not give Lotronex (alosetron) to a child.
This is not a list of all drugs or health problems that interact with Lotronex (alosetron).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Lotronex (alosetron) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Lotronex?
- Tell all of your health care providers that you take Lotronex (alosetron). This includes your doctors, nurses, pharmacists, and dentists.
- It may take 1 month to see the full effect.
- If you are 65 or older, use Lotronex (alosetron) with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Lotronex (alosetron) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Lotronex) best taken?
Use Lotronex (alosetron) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with or without food.
- Take Lotronex (alosetron) at the same time of day.
What do I do if I miss a dose?
- Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
What are some other side effects of Lotronex?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Lotronex?
- Store at room temperature.
- Protect from light.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Lotronex (alosetron) is refilled. If you have any questions about Lotronex (alosetron), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Lotronex (alosetron)
- Lotronex Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 21 Reviews – Add your own review/rating
- Generic Availability
- Drug class: serotoninergic neuroenteric modulators