Generic Name: Linaclotide (lin AK loe tide)
Brand Name: Linzess
Medically reviewed by Drugs.com. Last updated on Sep 25, 2020.
- Do not give to a child younger than 18 years of age. This medicine may cause harm if given to a child. Talk with the doctor.
Uses of Linaclotide:
What do I need to tell my doctor BEFORE I take Linaclotide?
- If you have an allergy to linaclotide or any other part of linaclotide.
- If you are allergic to linaclotide; any part of linaclotide; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have a bowel block.
This is not a list of all drugs or health problems that interact with linaclotide.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take linaclotide with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Linaclotide?
- Tell all of your health care providers that you take linaclotide. This includes your doctors, nurses, pharmacists, and dentists.
- If you get diarrhea, you will need to make sure to avoid getting dehydrated. Drink plenty of fluids and watch for weight loss. Talk with your doctor.
- Keep linaclotide away from children. Children who take linaclotide by accident may have very bad side effects, like very bad diarrhea and dehydration. If a child takes linaclotide by accident, get medical help right away.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
How is this medicine (Linaclotide) best taken?
Use linaclotide as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take on an empty stomach.
- Take 30 minutes before the first meal of the day.
- Swallow capsule whole. Do not chew, break, or crush.
- If you have trouble swallowing, you may mix linaclotide with applesauce or water. Follow how to mix as you have been told or read the package insert. If you are not sure how to mix linaclotide, call your doctor or pharmacist.
- If mixed, swallow the mixed drug right away. Do not store for use at a later time.
- Do not chew the mixture.
- Those who have feeding tubes may use linaclotide. Use as you have been told. Flush the feeding tube after linaclotide is given.
What do I do if I miss a dose?
- Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Black, tarry, or bloody stools.
- Swelling of belly.
- Sometimes, very bad diarrhea has led to the need to go to the hospital. Call your doctor right away if you have very bad diarrhea or diarrhea that will not go away. Call your doctor right away if you have signs of dehydration like very bad dizziness or passing out, not able to pass urine or change in how much urine is passed, or feeling very tired.
What are some other side effects of Linaclotide?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Stomach pain or diarrhea.
- Signs of a common cold.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Linaclotide?
- Store at room temperature.
- Store in the original container. Do not take out the antimoisture cube or packet.
- Keep lid tightly closed.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time linaclotide is refilled. If you have any questions about linaclotide, please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about linaclotide
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- En Español
- 726 Reviews
- Drug class: guanylate cyclase-C agonists
Other brands: Linzess