Lefamulin Injection
Generic name: Lefamulin Injection [ le-FAM-ue-lin ]
Brand name: Xenleta
Drug class: Miscellaneous antibiotics
Medically reviewed by Drugs.com. Last updated on Mar 27, 2024.
Uses of Lefamulin Injection:
- It is used to treat a type of bacterial infection.
What do I need to tell my doctor BEFORE I take Lefamulin Injection?
- If you are allergic to lefamulin injection; any part of lefamulin injection; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have liver disease.
- If you have ever had a long QT on ECG or other heartbeat that is not normal.
- If you are taking any drugs used for a heartbeat that is not normal.
- If you are taking any drugs that can cause a certain type of heartbeat that is not normal (prolonged QT interval). There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with lefamulin injection, like certain drugs that are used for HIV, infections, or seizures. There are many drugs that must not be taken with lefamulin injection.
- If you are breast-feeding. Do not breast-feed while you take lefamulin injection and for at least 2 days after your last dose.
This is not a list of all drugs or health problems that interact with lefamulin injection.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take lefamulin injection with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Lefamulin Injection?
- Tell all of your health care providers that you take lefamulin injection. This includes your doctors, nurses, pharmacists, and dentists.
- Do not use longer than you have been told. A second infection may happen.
- This medicine may cause harm to an unborn baby. A pregnancy test will be done before you start lefamulin injection to show that you are NOT pregnant.
- Women must use birth control while taking lefamulin injection and for some time after the last dose. Ask your doctor how long to use birth control. If you get pregnant, call your doctor right away.
How is this medicine (Lefamulin Injection) best taken?
Use lefamulin injection as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- A type of abnormal heartbeat (prolonged QT interval) can happen with lefamulin injection. Call your doctor right away if you have a fast heartbeat, a heartbeat that does not feel normal, or if you pass out.
- Diarrhea is common with antibiotics. Rarely, a severe form called C diff–associated diarrhea (CDAD) may happen. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen during or a few months after taking antibiotics. Call your doctor right away if you have stomach pain, cramps, or very loose, watery, or bloody stools. Check with your doctor before treating diarrhea.
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What are some other side effects of Lefamulin Injection?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Diarrhea.
- Upset stomach or throwing up.
- Irritation where lefamulin injection is given.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Lefamulin Injection?
- If you need to store lefamulin injection at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about lefamulin injection, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
More about lefamulin
- Check interactions
- Compare alternatives
- Reviews (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous antibiotics
- Breastfeeding
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