Hydrocortisone and Diphenhydramine Spray
Generic name: Hydrocortisone and Diphenhydramine Spray [ HYE-droe-KOR-ti-sone-and-DYE-fen-HYE-dra-meen ]
Brand name: HC DermaPax
Drug class: Miscellaneous topical agents
Medically reviewed by Drugs.com. Last updated on Mar 19, 2023.
Uses of Hydrocortisone and Diphenhydramine Spray:
- It is used to treat itching.
- It is used to treat skin irritation.
What do I need to tell my doctor BEFORE I take Hydrocortisone and Diphenhydramine Spray?
- If you are allergic to hydrocortisone and diphenhydramine spray; any part of hydrocortisone and diphenhydramine spray; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydrocortisone and diphenhydramine spray with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Hydrocortisone and Diphenhydramine Spray?
- Tell all of your health care providers that you take hydrocortisone and diphenhydramine spray. This includes your doctors, nurses, pharmacists, and dentists.
- Do not use with other products that have diphenhydramine.
- Do not use to treat diaper rash.
- If signs get worse or last for more than 7 days, talk with the doctor.
- This medicine may cause harm if swallowed. If hydrocortisone and diphenhydramine spray is swallowed, call a doctor or poison control center right away.
- Talk with the doctor before giving hydrocortisone and diphenhydramine spray to a child younger than 2 years of age.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using hydrocortisone and diphenhydramine spray while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Hydrocortisone and Diphenhydramine Spray) best taken?
Use hydrocortisone and diphenhydramine spray as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Do not take hydrocortisone and diphenhydramine spray by mouth. Use on your skin only. Keep out of your mouth and eyes (may burn).
- Wash your hands before and after use. Do not wash your hands after use if putting this on your hand.
- Wash affected skin and pat dry.
- Put a thin layer on the affected part.
What do I do if I miss a dose?
- This medicine is used on an as needed basis. Do not use more often than told by the doctor.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Very bad skin irritation.
What are some other side effects of Hydrocortisone and Diphenhydramine Spray?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Skin irritation.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Hydrocortisone and Diphenhydramine Spray?
- Store at room temperature.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about hydrocortisone and diphenhydramine spray, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
More about diphenhydramine / hydrocortisone topical
- Check interactions
- Compare alternatives
- Reviews (3)
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous topical agents
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.