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Here’s what to ask a doctor about hereditary angioedema

HC DermaPax

Generic Name: Hydrocortisone/Diphenhydramine Spray (HYE droe KOR ti sone/DYE fen HYE dra meen)
Brand Name: HC DermaPax

Uses of HC DermaPax:

  • It is used to treat itching.
  • It is used to treat skin irritation.

What do I need to tell my doctor BEFORE I take HC DermaPax?

  • If you have an allergy to HC DermaPax (hydrocortisone/diphenhydramine spray) or any part of HC DermaPax (hydrocortisone/diphenhydramine spray).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take HC DermaPax (hydrocortisone/diphenhydramine spray) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take HC DermaPax?

  • Tell all of your health care providers that you take HC DermaPax (hydrocortisone/diphenhydramine spray). This includes your doctors, nurses, pharmacists, and dentists.
  • Do not use with other products that have diphenhydramine.
  • Do not use to treat diaper rash.
  • If signs get worse or last for more than 7 days, talk with the doctor.
  • This medicine may cause harm if swallowed. If HC DermaPax (hydrocortisone/diphenhydramine spray) is swallowed, call a doctor or poison control center right away.
  • Talk with the doctor before giving HC DermaPax (hydrocortisone/diphenhydramine spray) to a child younger than 2 years of age.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using HC DermaPax (hydrocortisone/diphenhydramine spray) while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (HC DermaPax) best taken?

Use HC DermaPax (hydrocortisone/diphenhydramine spray) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Do not take HC DermaPax (hydrocortisone/diphenhydramine spray) by mouth. Use on your skin only. Keep out of your mouth and eyes (may burn).
  • Wash hands before and after use.
  • Wash affected skin and pat dry.
  • Put a thin layer on the affected part.

What do I do if I miss a dose?

  • Many times HC DermaPax (hydrocortisone/diphenhydramine spray) is used on an as needed basis. Do not use more often than told by the doctor.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad skin irritation.

What are some other side effects of HC DermaPax?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Skin irritation.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out HC DermaPax?

  • Store at room temperature.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about HC DermaPax (hydrocortisone/diphenhydramine spray), please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Disclaimer: This information should not be used to decide whether or not to take HC DermaPax (hydrocortisone/diphenhydramine spray) or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about HC DermaPax (hydrocortisone/diphenhydramine spray). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to HC DermaPax (hydrocortisone/diphenhydramine spray). This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using HC DermaPax (hydrocortisone/diphenhydramine spray).

Review Date: February 7, 2018