Generic Name: Diphenoxylate and Atropine Solution (dye fen OKS i late & A troe peen)
Brand Name: Lomotil
Uses of Diphenoxylate and Atropine Solution:
- It is used to treat loose stools (diarrhea).
What do I need to tell my doctor BEFORE I take Diphenoxylate and Atropine Solution?
- If you have an allergy to diphenoxylate, atropine, or any other part of diphenoxylate and atropine solution.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have any of these health problems: Loose stools caused by infection, loose stools caused by a very bad bowel problem (pseudomembranous colitis), or yellowing of the skin or eyes.
- If you are dehydrated or have electrolyte problems.
- If you are taking certain drugs used for depression like isocarboxazid, phenelzine, or tranylcypromine, or drugs used for Parkinson's disease like selegiline or rasagiline.
- If your child is younger than 2 years of age. Do not give this medicine to a child younger than 2 years of age.
This is not a list of all drugs or health problems that interact with diphenoxylate and atropine solution.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Diphenoxylate and Atropine Solution?
- Tell all of your health care providers that you take diphenoxylate and atropine solution. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine affects you.
- Avoid drinking alcohol while taking diphenoxylate and atropine solution.
- Talk with your doctor before you use other drugs and natural products that slow your actions.
- Talk with your doctor about drinking lots of fluids and other ways to prevent fluid loss. If you have a lot of fluid loss, you may have more side effects from this medicine.
- Keep away from children. Accidental exposure and overdose may result in very bad breathing problems or coma. These could lead to long lasting brain damage and sometimes death. If a child takes diphenoxylate and atropine solution by accident, get medical help right away.
- Use with care in children. Talk with the doctor.
- If you are 65 or older, use this medicine with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using diphenoxylate and atropine solution while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Diphenoxylate and Atropine Solution) best taken?
Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with or without food.
- Follow how to take diphenoxylate and atropine solution as you have been told by your doctor. Do not use more than you were told to use.
- Use the dropper that comes with this medicine to measure the drug.
What do I do if I miss a dose?
- This medicine is taken on an as needed basis. Do not take more often than told by the doctor.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- Trouble breathing, slow breathing, or shallow breathing.
- Numbness or tingling in the hands or feet.
- A fast heartbeat.
- Trouble passing urine.
- Fast breathing.
- Hallucinations (seeing or hearing things that are not there).
- Dry mouth.
- Larger pupils.
- Small pupils.
- Mood changes.
- Change in the way you act.
- Feeling confused.
- Change in eyesight.
- Very hard stools (constipation).
- Very bad belly pain.
- Swelling of belly.
What are some other side effects of Diphenoxylate and Atropine Solution?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling sleepy.
- Upset stomach or throwing up.
- Not hungry.
- Belly pain.
- Dry skin.
- Feeling tired or weak.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Diphenoxylate and Atropine Solution?
- Store at room temperature.
- Protect from light.
- Store in a dry place. Do not store in a bathroom.
- Throw away any part not used 90 days after opening.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about diphenoxylate and atropine solution, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about diphenoxylate and atropine solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using diphenoxylate and atropine solution.
Review Date: November 1, 2017
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