Generic Name: diltiazem (dil-TYE-a-zem)
Brand Name: Cardizem
Diltiazem tablets are used for:
Treating certain types of angina (chest pain). It may also be used for other conditions as determined by your doctor.
Diltiazem tablets are a calcium channel blocker. It works by relaxing (dilating) blood vessels, lowering blood pressure, and decreasing the heart rate, which lowers the workload of the heart. It also dilates coronary arteries, which increases blood flow to the heart.
Do NOT use diltiazem tablets if:
- you are allergic to any ingredient in diltiazem tablets
- you have certain heart problems (eg, sick sinus syndrome, second- or third-degree heart block) and do not have a pacemaker
- you have very low blood pressure or you have fluid buildup in the lungs during or soon after a heart attack
- you are taking rifampin
Contact your doctor or health care provider right away if any of these apply to you.
Before using diltiazem tablets:
Some medical conditions may interact with diltiazem tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have heart failure, a recent heart attack with lung congestion, heart block, a very slow heart rate, or other heart problems
- if you have low blood pressure or kidney or liver disease
- if you take other medicines for high blood pressure or heart conditions
Some MEDICINES MAY INTERACT with diltiazem tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Antiarrhythmics (eg, amiodarone, dronedarone), cimetidine, clonidine, HIV protease inhibitors (eg, atazanavir, indinavir), or tricyclic antidepressants (eg, desipramine) because they may increase the risk of diltiazem tablets's side effects, such as heart rhythm problems
- Moricizine or rifamycins (eg, rifampin) because they may decrease diltiazem tablets's effectiveness
- Benzodiazepines (eg, midazolam), beta-blockers (eg, metoprolol), buspirone, carbamazepine, cilostazol, cisapride, colchicine, corticosteroids (eg, prednisone), cyclosporine, digoxin, everolimus, fentanyl, HMG-CoA reductase inhibitors (eg, atorvastatin), hydantoins (eg, phenytoin), lurasidone, macrolide antibiotics (eg, erythromycin), macrolide immunomodulators (eg, tacrolimus), nifedipine, quinidine, ranolazine, theophylline, or vasopressin antagonists (eg, tolvaptan) because the risk of their side effects, some potentially life-threatening, may be increased by diltiazem tablets
This may not be a complete list of all interactions that may occur. Ask your health care provider if diltiazem tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use diltiazem tablets:
Use diltiazem tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take diltiazem tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Swallow diltiazem tablets whole. Do not break, crush, or chew before swallowing.
- Taking diltiazem tablets at the same time(s) each day will help you remember to take it.
- Continue to take diltiazem tablets even if you feel well. Do not miss any doses.
- If you miss a dose of diltiazem tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use diltiazem tablets.
Important safety information:
- Tell your doctor or dentist that you take diltiazem tablets before you receive any medical or dental care, emergency care, or surgery.
- Diltiazem tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use diltiazem tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Diltiazem tablets may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Do NOT take more than the recommended dose or stop taking diltiazem tablets without checking with your doctor.
- Severe skin reactions (Stevens-Johnson syndrome/toxic epidermal necrolysis) have happened with diltiazem tablets. They can cause serious health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
- Have your blood pressure and heart rate checked as you have been told by your doctor while taking diltiazem tablets.
- You may need to have an electrocardiogram (ECG) checked before starting diltiazem tablets and while taking it. Discuss any questions or concerns with your doctor.
- Use diltiazem tablets with caution in the ELDERLY; they may be more sensitive to its effects.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking diltiazem tablets while you are pregnant. Diltiazem tablets are found in breast milk. Do not breast-feed while taking diltiazem tablets.
Possible side effects of diltiazem tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Dizziness; facial flushing; headache; nausea; runny nose; sore throat; tiredness; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); fainting; severe or persistent dizziness or light-headedness; shortness of breath; slow or irregular heartbeat; sudden weight gain; swelling of the feet, ankles, or hands; symptoms of liver problems (eg, dark urine, pale stools, persistent loss of appetite, right-sided stomach pain, yellowing of the skin or eyes).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of diltiazem tablets:
Store diltiazem tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep diltiazem tablets out of the reach of children and away from pets.
- If you have any questions about diltiazem tablets, please talk with your doctor, pharmacist, or other health care provider.
- Diltiazem tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take diltiazem tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about diltiazem tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to diltiazem tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using diltiazem tablets.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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