Aspirin and Diphenhydramine

Generic name: Aspirin and Diphenhydramine [ AS-pir-in-& dye-fen-HYE-dra-meen ]
Brand name: Bayer PM
Drug class: Analgesic combinations

Uses of Aspirin and Diphenhydramine:

• It is used to treat sleep problems.
• It is used to ease pain.

What do I need to tell my doctor BEFORE I take Aspirin and Diphenhydramine?

For all patients taking aspirin and diphenhydramine:

• If you have an allergy to aspirin, diphenhydramine, or any other part of aspirin and diphenhydramine.
• If you are allergic to aspirin and diphenhydramine; any part of aspirin and diphenhydramine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you are more than 24 weeks pregnant.

Children:

• If your child is younger than 12 years of age. Do not give aspirin and diphenhydramine to a child younger than 12 years of age.
• If your child has or is getting better from flu signs, chickenpox, or other viral infections.

This is not a list of all drugs or health problems that interact with aspirin and diphenhydramine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take aspirin and diphenhydramine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Aspirin and Diphenhydramine?

• Tell all of your health care providers that you take aspirin and diphenhydramine. This includes your doctors, nurses, pharmacists, and dentists.
• Do not take more than what your doctor told you to take. Taking more than you are told may raise your chance of very bad side effects.
• Do not take aspirin and diphenhydramine for longer than you were told by your doctor.
• Avoid driving and doing other tasks or actions that call for you to be alert until you see how aspirin and diphenhydramine affects you.
• Avoid drinking alcohol while taking aspirin and diphenhydramine.
• Talk with your doctor before you use other drugs and natural products that slow your actions.
• Do not use with other products that have diphenhydramine.
• You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
• If you are taking aspirin to help prevent a heart attack, talk with your doctor.
• Use with care in children. Talk with the doctor.
• Do not give to children and teenagers who have or are getting better from flu signs, chickenpox, or other viral infections due to the chance of Reye's syndrome. Reye's syndrome causes very bad problems to the brain and liver.
• If you are 60 or older, use aspirin and diphenhydramine with care. You could have more side effects.
• Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using aspirin and diphenhydramine while you are pregnant.
• Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Aspirin and Diphenhydramine) best taken?

Use aspirin and diphenhydramine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take with a full glass of water.
• Take with or without food. Take with food if it causes an upset stomach.
• Take 30 to 60 minutes before bedtime if using for sleep. Do not take for more than 2 weeks in a row.

What do I do if I miss a dose?

• If you take aspirin and diphenhydramine on a regular basis, take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.
• Many times aspirin and diphenhydramine is taken on an as needed basis. Do not take more often than told by the doctor.

Related/similar drugs

acetaminophen, ibuprofen, tramadol, cyclobenzaprine, amitriptyline, diclofenac, naproxen, oxycodone, Tylenol, lorazepam

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of bleeding like throwing up or coughing up blood; vomit that looks like coffee grounds; blood in the urine; black, red, or tarry stools; bleeding from the gums; abnormal vaginal bleeding; bruises without a cause or that get bigger; or bleeding you cannot stop.
• Wheezing.
• Very bad dizziness or passing out.
• Very bad belly pain.
• Ringing in ears.
• Hearing loss.

What are some other side effects of Aspirin and Diphenhydramine?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Feeling sleepy.
• Feeling nervous and excitable.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Aspirin and Diphenhydramine?

• Store at room temperature.
• Store in a dry place. Do not store in a bathroom.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about aspirin and diphenhydramine, please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer