Generic Name: Rilonacept (ri LON a sept)
Brand Name: Arcalyst
Medically reviewed by Drugs.com. Last updated on May 3, 2019.
Uses of Arcalyst:
- It is used to treat cryopyrin-associated periodic syndromes (CAPS).
What do I need to tell my doctor BEFORE I take Arcalyst?
- If you have an allergy to rilonacept or any other part of Arcalyst (rilonacept).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have an infection.
- If you are taking any of these drugs: Abatacept, adalimumab, anakinra, certolizumab, etanercept, golimumab, infliximab, or rituximab.
This is not a list of all drugs or health problems that interact with Arcalyst (rilonacept).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Arcalyst (rilonacept) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Arcalyst?
- Tell all of your health care providers that you take Arcalyst (rilonacept). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine may cause high cholesterol and triglyceride levels. Talk with the doctor.
- Very bad infections have been reported with use of Arcalyst (rilonacept). If you have any infection, are taking antibiotics now or in the recent past, or have many infections, talk with your doctor.
- You may have more of a chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu. Some infections have been very bad and even deadly.
- This medicine may add to the chance of getting some types of cancer. Talk with the doctor.
- TB (tuberculosis) has been seen in patients started on Arcalyst (rilonacept). These patients were exposed to TB in the past, but never got the infection. You will be tested to see if you have been exposed to TB before starting Arcalyst (rilonacept).
- Talk with your doctor before getting any vaccines. Use of some vaccines with Arcalyst (rilonacept) may either raise the chance of an infection or make the vaccine not work as well.
- This medicine may affect growth in children and teens in some cases. They may need regular growth checks. Talk with the doctor.
- If you are taking warfarin, talk with your doctor. You may need to have your blood work checked more closely while you are taking it with Arcalyst (rilonacept).
- This medicine may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking Arcalyst (rilonacept), call your doctor right away.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Arcalyst) best taken?
Use Arcalyst (rilonacept) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into the fatty part of the skin on the top of the thigh, belly area, or upper arm.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Follow how to use as you have been told by the doctor or read the package insert.
- Wash your hands before and after use.
- This medicine needs to be mixed before use. Follow how to mix as you were told by the doctor.
- Do not use if the solution is cloudy, leaking, or has particles.
- This medicine is colorless to a faint yellow. Do not use if the solution changes color.
- Move the site where you give the shot with each shot.
- Do not give into skin that is irritated, bruised, red, infected, or scarred.
- Throw syringe away after use. Do not use the same syringe more than one time.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- Use a missed dose as soon as you think about it, up to the day before your next dose.
- Do not take 2 doses at the same time or extra doses.
- If you are not sure what to do if you miss a dose, call your doctor.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Numbness or tingling.
- Very bad irritation where the shot was given.
- Throwing up blood or throw up that looks like coffee grounds.
- Black, tarry, or bloody stools.
- Belly pain.
What are some other side effects of Arcalyst?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Irritation where the shot is given.
- Signs of a common cold.
- Stuffy nose.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Arcalyst?
- Store unopened vials in a refrigerator. Do not freeze.
- Store in original container.
- After mixing, you may store at room temperature for 3 hours.
- Protect unmixed and mixed product from light.
- Throw away any part left over after the dose is given.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Arcalyst (rilonacept), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Arcalyst (rilonacept)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- 2 Reviews
- Drug class: interleukin inhibitors
- FDA Approval History