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Adbry

Generic Name: tralokinumab-ldrm
Dosage Form: injection, for subcutaneous use

Medically reviewed by Judith Stewart, BPharm. Last updated on Dec 30, 2021.

What is Adbry?

  • Adbry is a prescription medicine used to treat adults with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. Adbry can be used with or without topical corticosteroids.
  • It is not known if Adbry is safe and effective in children.

Who should not use Adbry?

Do not use Adbry if you are allergic to tralokinumab or to any of the ingredients. See the end of this page for a complete list of ingredients.

Before using Adbry

Before you start treatment, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems.
  • have a parasitic (helminth) infection.
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” if you are treated with Adbry.
  • are pregnant or plan to become pregnant. It is not known whether Adbry will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether Adbry passes into your breast milk and if it can harm your baby.

What other drugs will affect Adbry?

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use Adbry?

  • See the detailed Instructions for Use that comes with your prescription for information on how to prepare and inject Adbry and how to properly store and throw away (dispose of) used Adbry prefilled syringes.
  • Use Adbry exactly as prescribed by your healthcare provider.
  • Your healthcare provider will tell you how much Adbry to inject and when to inject it.
  • Adbry comes as a single-dose (150 mg) prefilled syringe with needle guard.
  • Adbry is given as an injection under the skin (subcutaneous injection).
  • If your healthcare provider decides that you or a caregiver can give the injections, you or your caregiver should receive training on the right way to prepare and inject Adbry. Do not try to inject Adbry until you have been shown the right way by your healthcare provider.
  • If you miss a dose, inject the missed dose as soon as possible, then continue with your next dose at your regular scheduled time.
  • If you inject more Adbry than prescribed, call Poison Control at 1-800-222-1222.
  • Your healthcare provider may prescribe other medicines to use with Adbry. Use the other prescribed medicines exactly as your healthcare provider tells you to.

Dosage information

Usual Adult Dosage for Atopic Dermatitis

- initial dose of 600 mg (four 150 mg injections), followed by 300 mg (two 150 mg injections) administered every other week. A dosage of 300 mg every 4 weeks may be considered for patients below 100 kg who achieve clear or almost clear skin after 16 weeks of treatment.

- Use: treatment of moderate-to-severe atopic dermatitis in adult patients whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable.

Adbry side effects

Adbry can cause serious side effects, including:

  • Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using Adbry and tell your healthcare provider or get emergency help right away if you get any of the following symptoms:
    • breathing problems
    • swelling of the face, mouth, and tongue
    • hives
    • itching
    • fainting, dizziness, feeling lightheaded (low blood pressure)
    • skin rash
  • Eye problems. Tell your healthcare provider if you have any worsening eye problems, including eye pain or changes in vision.

The most common side effects include:

  • eye and eyelid inflammation, including redness, swelling, and itching
  • injection site reactions
  • high count of a certain white blood cell (eosinophilia)

These are not all of the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

General information about the safe and effective use of Adbry.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use this medicine for a condition for which it was not prescribed. Do not give it to other people, even if they have the same symptoms you have. It may harm them. You can ask your pharmacist or healthcare provider for information that is written for health professionals.

What are the ingredients in Adbry?

Active ingredient: tralokinumab-ldrm
Inactive ingredients: acetic acid, polysorbate 80, sodium acetate trihydrate, sodium chloride, and water for injection.

More about Adbry (tralokinumab)

Professional resources

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.