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Activella

Generic name: Estradiol and Norethindrone Tabletses-tra-DYE-ole-& nor-eth-IN-drone ]
Drug class: Sex hormone combinations

Medically reviewed by Drugs.com. Last updated on Mar 24, 2024.

Warning

  • Estrogens may raise the chance of endometrial cancer (cancer of the lining of the uterus).
  • Do not use estrogens to prevent heart disease or dementia. Using estrogens may raise the chances of having a heart attack, a stroke, breast cancer, ovarian cancer, a blood clot, or dementia.
  • Use estrogens with or without progestin for the shortest time needed at the lowest useful dose.

Uses of Activella:

What do I need to tell my doctor BEFORE I take Activella?

This is not a list of all drugs or health problems that interact with Activella (estradiol and norethindrone tablets).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Activella (estradiol and norethindrone tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Activella?

Soft, brittle bones (osteoporosis):

How is this medicine (Activella) best taken?

Use Activella (estradiol and norethindrone tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

What do I do if I miss a dose?

estradiol, Premarin, Estrace, Vagifem, conjugated estrogens, Climara

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

What are some other side effects of Activella?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Activella?

Consumer Information Use and Disclaimer

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.