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Zylet Side Effects

Generic Name: loteprednol / tobramycin ophthalmic

Note: This page contains side effects data for the generic drug loteprednol / tobramycin ophthalmic. It is possible that some of the dosage forms included below may not apply to the brand name Zylet.

In Summary

Common side effects of Zylet include: increased intraocular pressure and superficial punctate keratitis. Other side effects include: burning sensation and stinging sensation. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to loteprednol / tobramycin ophthalmic: ophthalmic suspension

As well as its needed effects, loteprednol / tobramycin ophthalmic may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking loteprednol / tobramycin ophthalmic, check with your doctor immediately:

More common:
  • Blurred vision
  • change in vision
  • feeling like something is in the eye
  • increased intraocular pressure
  • loss of vision
  • pain or irritation of the clear front part of the eye
  • sensitivity of the eyes to light
Less common:
  • Blurred vision or seeing blue-green halos around objects
  • decreased vision
  • difficulty seeing at night
  • discharge from the eye
  • dry eyes
  • eyelid burning, redness, itching, pain, or tenderness
  • fast heartbeat
  • fever
  • hives
  • hoarseness
  • irritation and swelling of the eye
  • itching
  • joint pain
  • lid itching and swelling
  • pain in the eye
  • rash
  • redness of the eyelid
  • redness of the skin
  • shortness of breath
  • stiffness or swelling
  • swelling of the eyelids, face, lips, hands, or feet
  • tightness in the chest
  • troubled breathing or swallowing
  • wheezing
Incidence not known:
  • Redness of the eye
  • tearing

Minor Side Effects

Some loteprednol / tobramycin ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Burning of the eye
  • headache
  • increased sensitivity of the eyes to light
  • stinging of the eye

For Healthcare Professionals

Applies to loteprednol / tobramycin ophthalmic: ophthalmic suspension

Ocular

Very common (10% or more): Injection (20%), superficial punctuate keratitis (15%), intraocular pressure increased (10%)
Frequency not reported: Vision disorder, discharge, itching, lacrimation disorder, photophobia, corneal deposit, ocular discomfort, eyelid disorder, unspecified eye disorder

Loteprednol etabonate:
Frequency not reported: Intraocular pressure increased, visual acuity defect, field defect, posterior subcapsular cataract formation, delayed wound healing, secondary ocular infection

Tobramycin:
Frequency not reported: Lid itching, conjunctival erythema, lid swelling[Ref]

Nervous system

Very common (10% or more): Headache (14%)[Ref]

Hypersensitivity

Tobramycin:
Frequency not reported: Hypersensitivity[Ref]

General

The most frequently reported side effects were injections and superficial punctate keratitis, increased intraocular pressure, and burning and stinging upon instillation.[Ref]

Local

Common (1% to 10%): Burning, stinging

Tobramycin:
Frequency not reported: Localized ocular toxicity[Ref]

References

1. "Product Information. Zylet (loteprednol-tobramycin ophthalmic)." Bausch and Lomb, Rochester, NY.

It is possible that some side effects of Zylet may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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