Zylet Side Effects
Generic Name: loteprednol / tobramycin ophthalmic
Medically reviewed by Drugs.com. Last updated on June 30, 2020.
Note: This document contains side effect information about loteprednol / tobramycin ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Zylet.
Common side effects of Zylet include: increased intraocular pressure and superficial punctate keratitis. Other side effects include: burning sensation and stinging sensation. See below for a comprehensive list of adverse effects.
For the Consumer
Side effects requiring immediate medical attention
Along with its needed effects, loteprednol/tobramycin ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking loteprednol / tobramycin ophthalmic:
- Blurred vision
- change in vision
- feeling like something is in the eye
- increased intraocular pressure
- loss of vision
- pain or irritation of the clear front part of the eye
- sensitivity of the eyes to light
- Blurred vision or seeing blue-green halos around objects
- decreased vision
- difficulty seeing at night
- discharge from the eye
- dry eyes
- eyelid burning, redness, itching, pain, or tenderness
- fast heartbeat
- irritation and swelling of the eye
- joint pain
- lid itching and swelling
- pain in the eye
- redness of the eyelid
- redness of the skin
- shortness of breath
- stiffness or swelling
- swelling of the eyelids, face, lips, hands, or feet
- tightness in the chest
- troubled breathing or swallowing
Incidence not known
- Redness of the eye
Side effects not requiring immediate medical attention
Some side effects of loteprednol / tobramycin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Burning of the eye
- increased sensitivity of the eyes to light
- stinging of the eye
For Healthcare Professionals
Applies to loteprednol / tobramycin ophthalmic: ophthalmic suspension
Very common (10% or more): Injection (20%), superficial punctuate keratitis (15%), intraocular pressure increased (10%)
Frequency not reported: Vision disorder, discharge, itching, lacrimation disorder, photophobia, corneal deposit, ocular discomfort, eyelid disorder, unspecified eye disorder
Frequency not reported: Intraocular pressure increased, visual acuity defect, field defect, posterior subcapsular cataract formation, delayed wound healing, secondary ocular infection
Very common (10% or more): Headache (14%)[Ref]
Frequency not reported: Hypersensitivity[Ref]
The most frequently reported side effects were injections and superficial punctate keratitis, increased intraocular pressure, and burning and stinging upon instillation.[Ref]
Common (1% to 10%): Burning, stinging
Frequency not reported: Localized ocular toxicity[Ref]
1. "Product Information. Zylet (loteprednol-tobramycin ophthalmic)." Bausch and Lomb, Rochester, NY.
More about Zylet (loteprednol / tobramycin ophthalmic)
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- 5 Reviews
- Drug class: ophthalmic steroids with anti-infectives
- FDA Approval History
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.