Zylet Side Effects

Generic name: loteprednol / tobramycin ophthalmic

Medically reviewed by Drugs.com. Last updated on Jul 2, 2024.

Note: This document provides detailed information about Zylet.

Applies to loteprednol/tobramycin ophthalmic: ophthalmic suspension Side Effects associated with loteprednol / tobramycin ophthalmic. Some dosage forms listed on this page may not apply specifically to the brand name Zylet.

Applies to loteprednol/tobramycin ophthalmic: ophthalmic suspension.

Precautions

If you will be using this medicine for more than a few weeks, your eye doctor will check your eyes at regular visits to make sure it is working properly and is not causing unwanted effects.

If your symptoms do not improve within a few days or if they become worse, check with your eye doctor.

Loteprednol and tobramycin eye drops is not for long-term use. Steroid eye drops may cause glaucoma (increased pressure inside the eye) or posterior subcapsular cataracts (a rare type of cataract) if used too long. Slow or delayed healing may also occur while you are using this medicine after cataract surgery. You will need to have regular eye exams with your doctor to check for these problems.

Do not wear contact lenses while you are using this medicine.

Serious side effects of Zylet

Along with its needed effects, loteprednol / tobramycin ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking loteprednol / tobramycin ophthalmic:

Other side effects of Zylet

Some side effects of loteprednol / tobramycin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to loteprednol / tobramycin ophthalmic: ophthalmic suspension.

General adverse events

The most frequently reported side effects were injections and superficial punctate keratitis, increased intraocular pressure, and burning and stinging upon instillation.^[Ref]

Nervous system

• Very common (10% or more): Headache (14%)^[Ref]

Hypersensitivity

Tobramycin:

• Frequency not reported: Hypersensitivity^[Ref]

Ocular

• Very common (10% or more): Injection (20%), superficial punctuate keratitis (15%), intraocular pressure increased (10%)
• Frequency not reported: Vision disorder, discharge, itching, lacrimation disorder, photophobia, corneal deposit, ocular discomfort, eyelid disorder, unspecified eye disorder

Loteprednol etabonate:

• Frequency not reported: Intraocular pressure increased, visual acuity defect, field defect, posterior subcapsular cataract formation, delayed wound healing, secondary ocular infection

Tobramycin:

• Frequency not reported: Lid itching, conjunctival erythema, lid swelling^[Ref]

Local

• Common (1% to 10%): Burning, stinging

Tobramycin:

• Frequency not reported: Localized ocular toxicity^[Ref]

See also:

Further information

Zylet side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer