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Udenyca Side Effects

Generic name: pegfilgrastim

Medically reviewed by Philip Thornton, DipPharm. Last updated on May 30, 2024.

Note: This document provides detailed information about Udenyca Side Effects associated with pegfilgrastim. Some dosage forms listed on this page may not apply specifically to the brand name Udenyca.

Applies to pegfilgrastim: subcutaneous solution.

Serious side effects of Udenyca

Along with its needed effects, pegfilgrastim (the active ingredient contained in Udenyca) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking pegfilgrastim:

More common

  • chills
  • cough
  • fever
  • sore throat
  • ulcers, sores, or white spots in the mouth

Rare

  • bluish lips or skin
  • pain, left upper abdomen or shoulder
  • tightness in the chest
  • trouble breathing

Incidence not known

  • black, tarry stools
  • bleeding gums
  • bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • blisters in the skin
  • blood in the urine or stools
  • chest pain
  • cloudy urine
  • decrease in how much or how often you urinate
  • difficulty with swallowing
  • dizziness
  • fainting or lightheadedness
  • fast heartbeat
  • flushing or redness of the skin
  • hives or welts, skin rash
  • itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • lower back or side pain
  • nausea
  • painful or difficult urination
  • pinpoint red spots on the skin
  • sores on the skin
  • stomach pain
  • swelling of the hands, ankles, feet, or lower legs
  • swollen glands
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusually warm skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking pegfilgrastim:

Symptoms of overdose

Other side effects of Udenyca

Some side effects of pegfilgrastim may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • belching
  • change in sense of taste
  • constipation
  • cracked lips
  • diarrhea
  • hair loss or thinning of the hair
  • heartburn
  • indigestion
  • joint pain
  • lack or loss of strength
  • loss of appetite
  • muscle soreness
  • swelling or inflammation of the mouth
  • trouble sleeping
  • vomiting
  • weakness, generalized
  • weight loss

Incidence not known

  • body produces substance that can bind to drug making it less effective or cause side effects

For healthcare professionals

Applies to pegfilgrastim: subcutaneous solution.

General

The most commonly reported side effects included bone pain, skeletal pain, medullary bone pain, and spontaneously reversible mild to moderate lactate dehydrogenase elevations.[Ref]

Musculoskeletal

Metabolic

Other

Dermatologic

Hematologic

Local

Gastrointestinal

Immunologic

Cardiovascular

Nervous system

Ocular

Respiratory

Hypersensitivity

Hepatic

Renal

Oncologic

Psychiatric

References

1. (2002) "Product Information. Neulasta (pegfilgrastim)." Amgen

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

Frequently asked questions

Further information

Udenyca side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.