Tryvio Side Effects

Generic name: aprocitentan

Medically reviewed by Drugs.com. Last updated on Jan 10, 2025.

Note: This document provides detailed information about Tryvio Side Effects associated with aprocitentan. Some dosage forms listed on this page may not apply specifically to the brand name Tryvio.

Applies to aprocitentan: oral tablets film-coated.

Side effects include:

Adverse effects reported in ≥2% of patients receiving aprocitentan (the active ingredient contained in Tryvio) include edema/fluid retention and anemia.

For healthcare professionals

Applies to aprocitentan: oral tablet.

General adverse events

The most frequently reported side effects included anemia, edema, and fluid retention.^[Ref]

Dermatologic

• Frequency not reported: Allergic dermatitis, erythema, rash

Hematologic

• Common (1% to 10%): Anemia/decreased hemoglobin
• Frequency not reported: Decreased hematocrit

Hepatic

• Frequency not reported: Hepatotoxicity, increased aminotransferases, increased ALT, increased AST

Hypersensitivity

• Uncommon (0.1% to 1%): Hypersensitivity
• Frequency not reported: Allergic edema

Hypersensitivity included rash, erythema, and allergic edema.

Metabolic

• Common (1% to 10%): Edema/fluid retention

Renal

• Frequency not reported: Decrease in estimated GFR

See also:

Further information

Tryvio side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer