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Tri-Sudo Side Effects

Generic name: pseudoephedrine / triprolidine

Medically reviewed by Last updated on Dec 17, 2020.

Note: This document contains side effect information about pseudoephedrine / triprolidine. Some of the dosage forms listed on this page may not apply to the brand name Tri-Sudo.

For the Consumer

Applies to pseudoephedrine / triprolidine: oral liquid, oral tablet

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Dizziness.
  • Feeling nervous and excitable.
  • Trouble sleeping.
  • Feeling sleepy.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

For Healthcare Professionals

Applies to pseudoephedrine/triprolidine: oral liquid, oral suspension extended release, oral syrup, oral tablet, oral tablet extended release

Nervous system

Rare (less than 0.1%): Hallucinations

Frequency not reported: Central nervous system depression or excitation, drowsiness, sleep disturbance[Ref]


Frequency not reported: Tachycardia[Ref]


Frequency not reported: Dry mouth, nose and throat[Ref]


Frequency not reported: Urinary retention[Ref]


Frequency not reported: Skin rashes (with or without irritation)[Ref]

More about Tri-Sudo (pseudoephedrine / triprolidine)

Consumer resources

Other brands
Aprodine, A-Phedrin, Allerfrim, Aphedrid, ... +3 more

Professional resources

Related treatment guides


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.