Tositumomab Side Effects
Applies to tositumomab: intravenous kit
Very common (10% or more): Rash, pruritus
Common (1% to 10%): Sweating[Ref]
Common (1% to 10%): Hypothyroidism[Ref]
Very common (10% or more): Positive serology for human anti-mouse antibodies (HAMA)[Ref]
Frequency not reported: Infusion reactions[Ref]
Very common (10% or more): Myalgia, arthralgia
Common (1% to 10%): Dizziness, somnolence
Postmarketing reports: Axonal neuropathy leading to quadriparesis[Ref]
Common (1% to 10%): Secondary malignancies (non-melanoma skin, colorectal, head and neck, breast, lung, bladder, melanoma, gastric)
Very common (10% or more): Asthenia, fever, infections, pain, chills, headache
Common (1% to 10%): Pneumonia[Ref]
1. "Product Information. Bexxar I 131 Therapeutic (iodine I 131 tositumomab)." GlaxoSmithKline, Research Triangle Park, NC.
2. "Product Information. BexxarTherapy (tositumomab)." GlaxoSmithKline Inc, Oakville, IA.
Some side effects may not be reported. You may report them to the FDA.