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Thyrolar-1 / 2 Side Effects

Generic Name: liotrix

Note: This document contains side effect information about liotrix. Some of the dosage forms listed on this page may not apply to the brand name Thyrolar-1 / 2.

For the Consumer

Applies to liotrix: oral tablet

Along with its needed effects, liotrix (the active ingredient contained in Thyrolar-1 / 2) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking liotrix:

Incidence not determined
  • Chest pain
  • constipation
  • depressed mood
  • difficulty in moving
  • discouragement
  • dryness of the eye
  • dry skin and hair
  • fast, irregular, pounding, or racing heartbeat or pulse
  • fear, nervousness
  • feeling cold
  • feeling sad or empty
  • fever
  • headache
  • hives or welts
  • hoarseness or husky voice
  • increased sweating
  • increased weight
  • increase in blood pressure
  • irritability
  • irritation
  • itching skin
  • joint pain, stiffness or swelling
  • lack of appetite
  • lack or loss of strength
  • loss of interest or pleasure
  • muscle aching or cramping
  • muscle pain or stiffness
  • nausea
  • redness of skin
  • shakiness in legs, arms, hands, feet
  • shortness of breath
  • skin rash
  • sleeplessness
  • slowed heartbeat
  • sluggishness
  • swelling of eyelids, face, lips, hands, or feet
  • swollen joints
  • tightness in chest
  • tiredness
  • trembling or shaking of hands or feet
  • trouble concentrating
  • troubled breathing or swallowing
  • trouble sleeping
  • unable to sleep
  • unusual tiredness or weakness
  • weight gain
  • wheezing

Some side effects of liotrix may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not determined

For Healthcare Professionals

Applies to liotrix: oral tablet


Adverse reactions other than those attributable to hyperthyroidism due to therapeutic overdose are rare. Excessive doses may result in a hypermetabolic state resembling in every respect the condition of endogenous origin.[Ref]


Postmarketing reports: Hypothyroidism, thyroid stimulating hormone (TSH) increased, TSH decreased[Ref]


Postmarketing reports: Palpitation, blood pressure increased, heart rate increased[Ref]


Postmarketing reports: Alopecia, dry skin, urticaria, hyperhidrosis, pruritus[Ref]


Postmarketing reports: Hypersensitivity[Ref]


Postmarketing reports: Arthralgia, myalgia[Ref]


Postmarketing reports: Keratoconjunctivitis sicca[Ref]


Postmarketing reports: Fatigue, sluggishness, weight increased, asthenia, chest pain[Ref]

Nervous system

Postmarketing reports: Headache, tremor[Ref]


Postmarketing reports: Nausea[Ref]


Postmarketing reports: Anxiety, depression, insomnia[Ref]


1. "Product Information. Thyrolar (liotrix)." Forest Pharmaceuticals, St. Louis, MO.

Some side effects of Thyrolar-1 / 2 may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.