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Thyrogen Side Effects

Generic name: thyrotropin alpha

Medically reviewed by Last updated on Jun 8, 2023.

Note: This document contains side effect information about thyrotropin alpha. Some dosage forms listed on this page may not apply to the brand name Thyrogen.

Applies to thyrotropin alpha: intramuscular powder for solution.

Serious side effects of Thyrogen

Along with its needed effects, thyrotropin alpha (the active ingredient contained in Thyrogen) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking thyrotropin alpha:

More common


Incidence not known

Get emergency help immediately if any of the following symptoms of overdose occur while taking thyrotropin alpha:

Symptoms of overdose

Other side effects of Thyrogen

Some side effects of thyrotropin alpha may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

Incidence not known

For Healthcare Professionals

Applies to thyrotropin alpha: intramuscular powder for injection.


Postmarketing reports: Hypersensitivity (including urticaria, rash, pruritus, flushing, respiratory signs/symptoms)


Common (1% to 10%): Fatigue

Postmarketing reports: Stroke, transient influenza-like symptoms (less than 48 hours, including fever over 100F, chills/shivering, myalgia/arthralgia, fatigue/asthenia/malaise, respiratory signs/symptoms), enlargement of residual thyroid tissue or metastases


Very common (10% or more): Nausea (11%)

Common (1% to 10%): Vomiting[Ref]


Postmarketing reports: Injection site reactions (including pain, erythema, bruising, pruritus)

Nervous system

Common (1% to 10%): Headache[Ref]


1. Product Information. Thyrogen (thyrotropin alfa). Genzyme Corporation. 2001;PROD.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.