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Synalar Side Effects

Generic name: fluocinolone topical

Medically reviewed by Drugs.com. Last updated on Jun 11, 2023.

Note: This document contains side effect information about fluocinolone topical. Some dosage forms listed on this page may not apply to the brand name Synalar.

Applies to fluocinolone topical: topical application cream, topical application oil, topical application ointment, topical application shampoo, topical application solution.

Serious side effects of Synalar

Along with its needed effects, fluocinolone topical (the active ingredient contained in Synalar) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fluocinolone topical:

More common

Less common

Incidence not known

Other side effects of Synalar

Some side effects of fluocinolone topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Incidence not known

For Healthcare Professionals

Applies to fluocinolone topical: compounding powder, topical cream, topical kit, topical lotion, topical oil, topical ointment, topical shampoo, topical solution.

General

The most commonly reported side effects were erythema, itching, irritation, and burning.[Ref]

Endocrine

Frequency not reported: Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome[Ref]

Immunologic

Common (1% to 10%): Facial herpes simplex, abscess, molluscum[Ref]

Local

Common (1% to 10%): Telangiectasia, erythema, itching, irritation, burning, hypopigmentation, hyperpigmentation, shiny skin, folliculitis, acneiform eruptions[Ref]

Nervous system

Frequency not reported: Intracranial hypertension (including bulging fontanelles, headaches, bilateral papilledema)

Dermatologic

Common (1% to 10%): Secondary atopic dermatitis, papules and pustules, keratosis pilaris, eczema, rash

Frequency not reported: Hypertrichosis, maceration of the skin, dermatitis, perioral dermatitis, acne or worsening of acne, acne rosacea[Ref]

Metabolic

Frequency not reported: Hyperglycemia, glucosuria[Ref]

References

1. Product Information. Synalar (fluocinolone topical). Syntex Laboratories Inc. 2001.

2. Product Information. Capex (fluocinolone topical). Galderma Laboratories Inc. 2003.

3. Product Information. Derma-Smoothe/FS (Body Oil) (fluocinolone topical). Hill Dermaceuticals Inc.

4. Cerner Multum, Inc. UK Summary of Product Characteristics.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.