Picato Side Effects
Generic name: ingenol topical
Medically reviewed by Drugs.com. Last updated on Aug 10, 2022.
Note: This document contains side effect information about ingenol topical. Some dosage forms listed on this page may not apply to the brand name Picato.
Summary
Common side effects of Picato include: dermal ulcer, localized vesiculation, skin erosion, swelling of skin, and erythema of skin. Continue reading for a comprehensive list of adverse effects.
Applies to ingenol topical: topical gel.
Side effects include:
Local skin reactions: Erythema, flaking/scaling, crusting, swelling, vesiculation/pustulation, erosion/ulceration.
Application site reactions: Pain, pruritus.
For Healthcare Professionals
Applies to ingenol topical: topical gel.
General
The most commonly reported side effects were local skin responses including erythema, flaking/scaling, crusting, swelling, vesiculation/postulation, and erosion.[Ref]
Hypersensitivity
Frequency not reported: Hypersensitivity reactions[Ref]
Local
Very common (10% or more): Application site erythema (up to 94%), application site exfoliation (up to 90%), application site scab (up to 80%), application site swelling (up to 79%), application site erosion/ulceration (up to 32%), application site vesicles (up to 20%), application site pain (including application site burning) (up to 15%)
Common (1% to 10%): Application site pruritus, application site irritation
Uncommon (0.1% to 1%): Application site discharge, application site paresthesia, application site ulcer, application site warmth[Ref]
Dermatologic
Very common (10% or more): Flaking/scaling (85%), crusting (80%), vesiculation/postulation (56%)
Postmarketing reports: Allergic contact dermatitis, application site pigmentation changes, application site scarring, chemical conjunctivitis[Ref]
Immunologic
Very common (10% or more): Application site pustules (up to 43%)
Common (1% to 10%): Application site infection
Postmarketing reports: Herpes zoster[Ref]
Nervous system
Common (1% to 10%): Headache[Ref]
Ocular
Common (1% to 10%): Eye lid edema, periorbital edema
Uncommon (0.1% to 1%): Eyelid pain
Frequency not reported: Chemical conjunctivitis, corneal burn, eyelid ptosis[Ref]
Other
Very common (10% or more): Swelling (79%)[Ref]
More about Picato (ingenol topical)
- Reviews (19)
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: topical antineoplastics
- Breastfeeding
Patient resources
Professional resources
Related treatment guides
References
1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
2. Cerner Multum, Inc. "Australian Product Information." O 0
3. "Product Information. Picato (ingenol topical)." Leo Pharma Inc (2012):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.