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Nuplazid Side Effects

Generic Name: pimavanserin

Note: This page contains side effects data for the generic drug pimavanserin. It is possible that some of the dosage forms included below may not apply to the brand name Nuplazid.

For the Consumer

Applies to pimavanserin: oral tablet

As well as its needed effects, pimavanserin (the active ingredient contained in Nuplazid) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking pimavanserin, check with your doctor immediately:

Incidence not known:
  • Chest pain or discomfort
  • fainting
  • irregular or slow heart rate
  • shortness of breath

Minor Side Effects

Some pimavanserin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Bloating or swelling of the face, arms, hands, lower legs, or feet
  • confusion
  • nausea
  • rapid weight gain
  • unusual weight gain or loss
Less common:
  • Change in walking and balance
  • clumsiness or unsteadiness
  • difficulty having a bowel movement (stool)

For Healthcare Professionals

Applies to pimavanserin: oral tablet

General

The most commonly reported side effects are peripheral edema and confusional state.[Ref]

Psychiatric

Hallucinations (e.g., visual, auditory, tactile, and somatic)[Ref]

Common (1% to 10%): Confusional state, hallucinations[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, constipation[Ref]

Cardiovascular

Common (1% to 10%): Peripheral edema[Ref]

Nervous system

Common (1% to 10%): Gait disturbance[Ref]

Other

Common (1% to 10%): Fatigue[Ref]

Genitourinary

Common (1% to 10%): Urinary tract infection[Ref]

References

1. "Product Information. Nuplazid (pimavanserin)." Accelis Pharma, East Windsor, NJ.

It is possible that some side effects of Nuplazid may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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