Skip to main content

Nevanac Side Effects

Generic name: nepafenac ophthalmic

Medically reviewed by Last updated on May 5, 2022.

Note: This document contains side effect information about nepafenac ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Nevanac.

For the Consumer

Applies to nepafenac ophthalmic: ophthalmic suspension

Side effects requiring immediate medical attention

Along with its needed effects, nepafenac ophthalmic (the active ingredient contained in Nevanac) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking nepafenac ophthalmic:

More common

  • Blurred vision
  • change in vision
  • decrease in vision
  • loss of vision

Less common

  • Eye pain
  • itching of the eye
  • swelling and/or redness of the eye and lining of the eyelid

Side effects not requiring immediate medical attention

Some side effects of nepafenac ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Feeling of having something in the eye
  • sticky sensation of the eyelids

Less common

  • Change in color vision
  • cough
  • crusting in the corner of the eye
  • difficulty seeing at night
  • dizziness
  • dry eyes
  • fever
  • headache
  • increased sensitivity of the eyes to sunlight
  • nausea or vomiting
  • nervousness
  • pounding in the ears
  • seeing flashes or sparks of light
  • seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
  • slow or fast heartbeat
  • stuffy or runny nose
  • tenderness around the eyes and cheekbones
  • tightness of the chest or wheezing
  • troubled breathing

For Healthcare Professionals

Applies to nepafenac ophthalmic: ophthalmic suspension


Common (1% to 10%): Capsular opacity, conjunctival edema, corneal edema, dry eye, foreign body sensation in eyes, increased intraocular pressure, lid margin crusting, ocular discomfort, ocular hyperemia, ocular pain, ocular pruritus, photophobia, punctate keratitis, reduced visual acuity, sticky sensation, tearing, vitreous detachment

Uncommon (0.1% to 1%): Corneal epithelium defect, eye pain, eyelid margin crusting, keratitis

Rare (0.01% to 0.1%): Allergic conjunctivitis, blepharitis, choroidal effusion, conjunctival hyperemia, corneal deposits, eye discharge, eye irritation, eye pruritus, increased lacrimation, iritis

Frequency not reported: Blurred vision, corneal opacity, corneal perforation, corneal scar, corneal thinning, eye swelling, impaired healing (cornea), ulcerative keratitis

Postmarketing reports: Corneal adverse reactions, sight threatening corneal adverse reactions[Ref]


Common (1% to 10%): Nausea, vomiting[Ref]

Nervous system

Common (1% to 10%): Headache

Rare (0.01% to 0.1%): Dizziness[Ref]


Common (1% to 10%): Hypertension

Frequency not reported: Increased blood pressure[Ref]


Common (1% to 10%): Sinusitis[Ref]


Rare (0.01% to 0.1%): Allergic dermatitis, cutis laxa, dermatochalasis[Ref]


Rare (0.01% to 0.1%): Hypersensitivity[Ref]


Frequency not reported: Increased bleeding time[Ref]


Frequency not reported: Delayed healing[Ref]


1. "Product Information. Nevanac (nepafenac ophthalmic)." Alcon Laboratories Inc (2005):

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.