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Neo-Poly-Dex Side Effects

Generic Name: dexamethasone / neomycin / polymyxin b ophthalmic

Note: This page contains side effects data for the generic drug dexamethasone / neomycin / polymyxin b ophthalmic. It is possible that some of the dosage forms included below may not apply to the brand name Neo-Poly-Dex.

For the Consumer

Applies to dexamethasone / neomycin / polymyxin b ophthalmic: eye drops, eye ointment

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning or stinging when you first put the medicine in your eye; dry, flaky skin; irritation; itching; redness; swelling.

Seek medical attention right away if any of these SEVERE side effects occur while taking dexamethasone / neomycin / polymyxin b ophthalmic:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; continued burning or itching; eye pain.

For Healthcare Professionals

Applies to dexamethasone / neomycin / polymyxin b ophthalmic: ophthalmic ointment, ophthalmic suspension


The most frequently reported side effects were ocular discomfort, keratitis, eye irritation, and allergic sensitization.[Ref]


Uncommon (0.1% to 1%): Keratitis, intraocular pressure increased, vision blurred, photophobia, mydriasis, eyelid ptosis, eye pain, eye swelling, eye pruritus, ocular discomfort, foreign body sensation, eye irritation, ocular hyperemia, lacrimation increased
Frequency not reported: Corneal thinning

Frequency not reported: Intraocular pressure increased, glaucoma, visual acuity reduced, visual field defect, posterior subcapsular cataract formation, globe perforation, keratitis, conjunctivitis, corneal ulcer, conjunctival hyperemia, optic nerve damage, wound healing delayed[Ref]


Uncommon (0.1% to 1%): Hypersensitivity
Frequency not reported: Allergic sensitization[Ref]

Nervous system

Frequency not reported: Headache[Ref]


Frequency not reported: Secondary ocular infection developed, fungal infection developed[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Maxitrol (dexamethasone/neomycin/polymyxin B ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

It is possible that some side effects of Neo-Poly-Dex may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.