Mozobil Side Effects

Generic name: plerixafor

Medically reviewed by Drugs.com. Last updated on Dec 2, 2024.

Note: This document provides detailed information about Mozobil.

Applies to plerixafor: subcutaneous solution Side Effects associated with plerixafor. Some dosage forms listed on this page may not apply specifically to the brand name Mozobil.

Applies to plerixafor: subcutaneous solution.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Using this medicine while you are pregnant can harm your unborn baby. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Male and female patients should use an effective form of birth control during treatment and for 1 week after the last dose. If a pregnancy occurs while you are using this medicine, tell your doctor right away.

This medicine may enlarge your spleen, which could possibly burst. Check with your doctor right away if you have pain in the upper left part of your stomach or at the tip of your left shoulder.

Tell your doctor right away if you have a slow heartbeat, severe, unusual tiredness or weakness, cold sweats, confusion, or dizziness, faintness, or lightheadedness when getting up from a lying or sitting position after you get the injection.

This medicine may cause a serious allergic reaction, called anaphylaxis, which can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving this medicine.

This medicine may cause diarrhea, nausea, vomiting, or stomach pain in some patients. Ask your doctor or nurse about other ways to control these side effects.

Serious side effects of Mozobil

Along with its needed effects, plerixafor (the active ingredient contained in Mozobil) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking plerixafor:

Other side effects of Mozobil

Some side effects of plerixafor may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to plerixafor: subcutaneous solution.

Gastrointestinal adverse events

• Very common (10% or more): Diarrhea (up to 37%), nausea (up to 34%), vomiting (up to 10%)
• Common (1% to 10%): Flatulence, abdominal pain, abdominal distension, dry mouth, stomach discomfort, hypoesthesia oral, constipation, dyspepsia^[Ref]

Local

• Very common (10% or more): Injection site reactions (up to 34%)^[Ref]

Other

• Very common (10% or more): Fatigue (up to 27%)
• Common (1% to 10%): Malaise^[Ref]

Nervous system

• Very common (10% or more): Headache (up to 22%), paresthesia (up to 20.6%), dizziness (up to 11%)
• Uncommon (0.1% to 1%): Vasovagal reactions^[Ref]

Musculoskeletal

• Very common (10% or more): Arthralgia (up to 13%)
• Common (1% to 10%): Musculoskeletal pain^[Ref]

Dermatologic

• Common (1% to 10%): Hyperhidrosis, erythema^[Ref]

Hematologic

• Common (1% to 10%): Hyperleukocytosis
• Frequency not reported: Thrombocytopenia
• Postmarketing reports: Splenomegaly and splenic rupture^[Ref]

Psychiatric

• Common (1% to 10%): Insomnia
• Uncommon (0.1% to 1%): Abnormal dreams, nightmares^[Ref]

Immunologic

• Uncommon (0.1% to 1%): Allergic reactions
• Postmarketing reports: Anaphylactic reactions including anaphylactic shock^[Ref]

Cardiovascular

• Rare (less than 0.1%): Myocardial infarction^[Ref]

See also:

Further information

Mozobil side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer