Monistat 1-Day Pre-Filled Applicator Side Effects
Generic Name: tioconazole topical
Note: This page contains information about the side effects of tioconazole topical. Some of the dosage forms included on this document may not apply to the brand name Monistat 1-Day Pre-Filled Applicator.
For the Consumer
Applies to tioconazole topical: topical cream
In addition to its needed effects, some unwanted effects may be caused by tioconazole topical (the active ingredient contained in Monistat 1-Day Pre-Filled Applicator). In the event that any of these side effects do occur, they may require medical attention.
If any of the following side effects occur while taking tioconazole topical, check with your doctor or nurse as soon as possible:Less common:
- skin rash
- or other signs of skin irritation not present before use of this medicine
For Healthcare Professionals
Applies to tioconazole topical: vaginal ointment w/applicator
Local side effects have been commonly reported. These have involved the genitourinary area (occurring in up to 7% of treated patients), and have included burning, itching, and, less commonly, pain, irritation, and dryness.[Ref]
Hypersensitivity side effects have included contact dermatitis in patients using a topical nail solution (not available in the US). Most patients had been using the product for several weeks when dermatitis developed. Cross-sensitivity to other imidazoles has been reported.[Ref]
1. Clissold SP, Heel RC "Tioconazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses." Drugs 31 (1986): 29-51
2. "Product Information. Vagistat-1 (tioconazole)." Bristol-Myers Squibb, Princeton, NJ.
3. Stein GE, Gurwith D, Mummaw N, Gurwith M "Single-dose tioconazole compared with 3-day clotrimazole treatment in vulvovaginal candidiasis." Antimicrob Agents Chemother 29 (1986): 969-71
4. Onayemi O, Aldridge RD, Shaw S "Allergic contact dermatitis from tioconazole. A report of 2 cases." Contact Dermatitis 26 (1992): 193-4
5. Brunelli D, Vincenzi C, Morelli R, Tosti A "Contact dermatitis from tioconazole." Contact Dermatitis 27 (1992): 120
6. Piletta P, Pasche-Koo F, Saurat JH "Contact dermatitis from tioconazole mimicking "one hand two feet syndrome"." Contact Dermatitis 28 (1993): 308
7. Jones SK, Kennedy CT "Contact dermatitis from tioconazole." Contact Dermatitis 22 (1990): 122-3
8. Marren P, Powell S "Contact sensitivity to tioconazole and other imidazoles." Contact Dermatitis 27 (1992): 129-30
9. Gibson G, Buckley A, Murphy GM "Allergic contact dermatitis from tioconazole without cross- sensitivity to other imidazoles." Contact Dermatitis 30 (1994): 308
10. Stubb S, Heikkila H, Reitamo S, Forstrom L "Contact allergy to tioconazole." Contact Dermatitis 26 (1992): 155-8
11. Faria A, Goncalo S, Goncalo M, Freitas C, Baptista PP "Allergic contact dermatitis from tioconazole." Contact Dermatitis 35 (1996): 250-2
12. Quirino AP, Barros MA "Contact dermatitis from tioconazole." Contact Dermatitis 30 (1994): 240-1
13. Izu R, Aguirre A, Gonzalez M, Diaz-Perez JL "Contact dermatitis from tioconazole with cross-sensitivity to other imidazoles." Contact Dermatitis 26 (1992): 130-1
Not all side effects for Monistat 1-Day Pre-Filled Applicator may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
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