Skip to main content

Lutetium lu 177 dotatate Side Effects

Medically reviewed by Last updated on Jan 28, 2024.

Applies to lutetium lu 177 dotatate: intravenous solution.

Serious side effects

Along with its needed effects, lutetium lu 177 dotatate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking lutetium lu 177 dotatate:

More common

Less common

Other side effects

Some side effects of lutetium lu 177 dotatate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to lutetium lu 177 dotatate: intravenous solution.


Common (1% to 10%): Lymphopenia, leukopenia, neutropenia, thrombocytopenia, anemia[Ref]


Common (1% to 10%): Back pain, pain in extremity, myalgia, neck pain[Ref]


Common (1% to 10%): Decreased appetite, hyperglycemia, hypocalcemia, hypokalemia, hyperkalemia, hypernatremia, hypoglycemia[Ref]


Common (1% to 10%): Anxiety[Ref]


Common (1% to 10%): GGT increased, alkaline phosphatase increased, AST increased, ALT increased, blood bilirubin increased[Ref]


Common (1% to 10%): Cough[Ref]


Common (1% to 10%): Fatigue, peripheral edema, pyrexia[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness, dysgeusia[Ref]


Common (1% to 10%): Renal failure (glomerular filtration rate decreased, acute kidney injury, acute prerenal failure, azotemia, renal disorder, renal failure, renal impairment); hyperuricemia; creatinine increased[Ref]


Common (1% to 10%): Atrial fibrillation, flushing, hypertension[Ref]


Common (1% to 10%): Alopecia


Common (1% to 10%): Nausea, vomiting abdominal pain, diarrhea, constipation[Ref]


Common (1% to 10%): Radiation related urinary tract toxicity (dysuria, micturition urgency, nocturia, pollakiuria, renal colic, renal pain, urinary tract pain and urinary incontinence)


1. (2022) "Product Information. Lutathera (lutetium Lu 177 dotatate)." Advanced Accelerator Applications

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.